| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | Thunder | 115 | Warriors | 116 |
| November | 6, 2020 | Thunder | 121 | Clippers | 128 |
| November | 8, 2020 | Kings | 122 | Thunder | 141 |
| November | 13, 2020 | Celtics | 102 | Thunder | 124 |
| November | 17, 2020 | Suns | 123 | Thunder | 114 |
| November | 19, 2020 | Clippers | 127 | Thunder | 118 |
| November | 21, 2020 | Thunder | 109 | Hornets | 121 |
| November | 22, 2020 | Thunder | 116 | Wizards | 112 |
| November | 25, 2020 | Pelicans | 115 | Thunder | 109 |
| November | 27, 2020 | Thunder | 103 | Cavaliers | 121 |
| November | 28, 2020 | Rockets | 132 | Thunder | 108 |
| November | 30, 2020 | Thunder | 86 | Mavericks | 137 |
| December | 2, 2020 | Suns | 90 | Thunder | 91 |
| December | 4, 2020 | Knicks | 91 | Thunder | 100 |
| December | 7, 2020 | Thunder | 90 | Suns | 100 |
| December | 9, 2020 | Thunder | 71 | Kings | 139 |
| December | 11, 2020 | Thunder | 92 | Warriors | 115 |
| December | 14, 2020 | Hornets | 96 | Thunder | 98 |
| December | 15, 2020 | Nuggets | 108 | Thunder | 105 |
| December | 19, 2020 | Cavaliers | 134 | Thunder | 91 |
| December | 21, 2020 | Hawks | 119 | Thunder | 126 |
| December | 25, 2020 | Thunder | 86 | Pistons | 115 |
| December | 27, 2020 | Thunder | 108 | Nets | 103 |
| December | 29, 2020 | Thunder | 109 | Bulls | 123 |
| January | 1, 2021 | Jazz | 104 | Thunder | 72 |
| January | 3, 2021 | Thunder | 103 | Pelicans | 136 |
| January | 5, 2021 | Thunder | 95 | Nuggets | 114 |
| January | 6, 2021 | Clippers | 119 | Thunder | 81 |
| January | 8, 2021 | Bulls | 124 | Thunder | 105 |
| January | 11, 2021 | Thunder | 107 | Kings | 128 |
| January | 13, 2021 | Thunder | 89 | Jazz | 139 |
| January | 14, 2021 | Wolves | 119 | Thunder | 85 |
| January | 15, 2021 | Thunder | 77 | Rockets | 125 |
| January | 18, 2021 | Thunder | 106 | Suns | 145 |
| January | 20, 2021 | Thunder | 111 | Mavericks | 134 |
| January | 21, 2021 | Mavericks | 127 | Thunder | 105 |
| January | 23, 2021 | Thunder | 89 | Lakers | 115 |
| January | 25, 2021 | Thunder | 114 | Trailblazers | 138 |
| January | 27, 2021 | Wizards | 114 | Thunder | 113 |
| January | 29, 2021 | Wolves | 102 | Thunder | 103 |
| January | 31, 2021 | Thunder | 100 | Spurs | 142 |
| February | 2, 2021 | Spurs | 140 | Thunder | 94 |
| February | 6, 2021 | Thunder | 109 | Hawks | 118 |
| February | 13, 2021 | Lakers | 108 | Thunder | 94 |
| February | 15, 2021 | Thunder | 101 | 76ers | 154 |
| February | 17, 2021 | Thunder | 94 | Knicks | 114 |
| February | 18, 2021 | Trailblazers | 119 | Thunder | 118 |
| February | 20, 2021 | Pelicans | 126 | Thunder | 106 |
| February | 23, 2021 | Bucks | 110 | Thunder | 134 |
| February | 25, 2021 | Thunder | 107 | Magic | 116 |
| February | 28, 2021 | Thunder | 127 | Heat | 101 |
| March | 3, 2021 | Thunder | 114 | Celtics | 122 |
| March | 5, 2021 | Magic | 123 | Thunder | 115 |
| March | 7, 2021 | Grizzlies | 115 | Thunder | 97 |
| March | 9, 2021 | Thunder | 89 | Rockets | 125 |
| March | 11, 2021 | Trailblazers | 134 | Thunder | 100 |
| March | 14, 2021 | Thunder | 95 | Pelicans | 135 |
| March | 16, 2021 | Jazz | 94 | Thunder | 78 |
| March | 17, 2021 | Kings | 112 | Thunder | 86 |
| March | 20, 2021 | Thunder | 101 | Nuggets | 120 |
| March | 22, 2021 | 76ers | 135 | Thunder | 126 |
| March | 24, 2021 | Thunder | 115 | Spurs | 132 |
| March | 25, 2021 | Grizzlies | 117 | Thunder | 96 |
| March | 27, 2021 | Thunder | 102 | Wolves | 123 |
| March | 29, 2021 | Thunder | 132 | Trailblazers | 123 |
| March | 30, 2021 | Thunder | 90 | Clippers | 124 |
| April | 2, 2021 | Thunder | 110 | Jazz | 115 |
| April | 4, 2021 | Nets | 92 | Thunder | 109 |
| April | 5, 2021 | Thunder | 107 | Pacers | 118 |
| April | 7, 2021 | Warriors | 106 | Thunder | 111 |
| April | 9, 2021 | Heat | 110 | Thunder | 124 |
| April | 11, 2021 | Raptors | 133 | Thunder | 110 |
| April | 13, 2021 | Thunder | 97 | Raptors | 114 |
| April | 16, 2021 | Thunder | 114 | Grizzlies | 139 |
| April | 18, 2021 | Pacers | 124 | Thunder | 119 |
| April | 20, 2021 | Nuggets | 114 | Thunder | 125 |
| April | 22, 2021 | Mavericks | 113 | Thunder | 132 |
| April | 24, 2021 | Lakers | 143 | Thunder | 135 |
| April | 27, 2021 | Pistons | 128 | Thunder | 118 |
| April | 29, 2021 | Thunder | 93 | Wolves | 113 |
| April | 30, 2021 | Rockets | 102 | Thunder | 126 |
| May | 1, 2021 | Thunder | 97 | Bucks | 128 |