| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Pistons | 94 | Spurs | 117 |
| November | 4, 2022 | Spurs | 110 | Wolves | 109 |
| November | 7, 2022 | Spurs | 108 | Wolves | 106 |
| November | 8, 2022 | Hawks | 107 | Spurs | 126 |
| November | 11, 2022 | Suns | 100 | Spurs | 104 |
| November | 12, 2022 | Spurs | 122 | Grizzlies | 99 |
| November | 15, 2022 | Kings | 106 | Spurs | 122 |
| November | 17, 2022 | Spurs | 88 | Suns | 115 |
| November | 19, 2022 | Grizzlies | 102 | Spurs | 116 |
| November | 21, 2022 | Trailblazers | 104 | Spurs | 116 |
| November | 24, 2022 | Spurs | 122 | Knicks | 106 |
| November | 28, 2022 | Spurs | 141 | Hornets | 111 |
| November | 30, 2022 | Thunder | 122 | Spurs | 90 |
| December | 1, 2022 | Spurs | 134 | Celtics | 105 |
| December | 3, 2022 | Clippers | 126 | Spurs | 122 |
| December | 5, 2022 | Spurs | 127 | Nuggets | 114 |
| December | 7, 2022 | Spurs | 107 | Thunder | 130 |
| December | 9, 2022 | Spurs | 102 | Pelicans | 114 |
| December | 12, 2022 | Spurs | 115 | Thunder | 132 |
| December | 15, 2022 | Spurs | 97 | Pistons | 91 |
| December | 16, 2022 | Spurs | 105 | 76ers | 122 |
| December | 18, 2022 | Rockets | 108 | Spurs | 104 |
| December | 20, 2022 | Spurs | 102 | Raptors | 108 |
| December | 21, 2022 | Spurs | 100 | Lakers | 108 |
| December | 23, 2022 | Spurs | 92 | Trailblazers | 108 |
| December | 26, 2022 | Spurs | 91 | Cavaliers | 95 |
| December | 27, 2022 | Suns | 122 | Spurs | 120 |
| December | 30, 2022 | Pelicans | 97 | Spurs | 145 |
| January | 2, 2023 | Grizzlies | 106 | Spurs | 118 |
| January | 4, 2023 | Spurs | 102 | Magic | 111 |
| January | 5, 2023 | Knicks | 98 | Spurs | 125 |
| January | 8, 2023 | Spurs | 109 | Heat | 105 |
| January | 9, 2023 | Warriors | 114 | Spurs | 99 |
| January | 12, 2023 | Hornets | 113 | Spurs | 110 |
| January | 15, 2023 | Spurs | 114 | Kings | 102 |
| January | 17, 2023 | Spurs | 98 | Warriors | 128 |
| January | 21, 2023 | Nets | 92 | Spurs | 115 |
| January | 23, 2023 | Mavericks | 114 | Spurs | 108 |
| January | 26, 2023 | Spurs | 107 | Hawks | 130 |
| January | 28, 2023 | Spurs | 82 | Nets | 115 |
| January | 30, 2023 | Magic | 94 | Spurs | 117 |
| February | 1, 2023 | Lakers | 92 | Spurs | 129 |
| February | 5, 2023 | Warriors | 115 | Spurs | 138 |
| February | 6, 2023 | Spurs | 120 | Mavericks | 121 |
| February | 11, 2023 | Spurs | 125 | Lakers | 113 |
| February | 14, 2023 | Mavericks | 120 | Spurs | 125 |
| February | 17, 2023 | Pacers | 122 | Spurs | 130 |
| February | 20, 2023 | Spurs | 123 | Wizards | 104 |
| February | 21, 2023 | Raptors | 128 | Spurs | 125 |
| February | 25, 2023 | Cavaliers | 120 | Spurs | 122 |
| February | 27, 2023 | Kings | 106 | Spurs | 119 |
| February | 28, 2023 | Rockets | 102 | Spurs | 127 |
| March | 1, 2023 | Bucks | 106 | Spurs | 116 |
| March | 4, 2023 | Jazz | 87 | Spurs | 121 |
| March | 6, 2023 | Spurs | 124 | Jazz | 115 |
| March | 7, 2023 | Nuggets | 118 | Spurs | 115 |
| March | 8, 2023 | Spurs | 136 | Suns | 133 |
| March | 11, 2023 | Jazz | 93 | Spurs | 142 |
| March | 12, 2023 | Bulls | 111 | Spurs | 110 |
| March | 14, 2023 | Thunder | 140 | Spurs | 110 |
| March | 17, 2023 | Spurs | 127 | Clippers | 115 |
| March | 19, 2023 | Spurs | 104 | Jazz | 125 |
| March | 21, 2023 | Spurs | 130 | Kings | 121 |
| March | 23, 2023 | Spurs | 130 | Clippers | 114 |
| March | 25, 2023 | Wizards | 121 | Spurs | 119 |
| March | 26, 2023 | Spurs | 111 | Pacers | 125 |
| March | 28, 2023 | Spurs | 133 | Grizzlies | 117 |
| March | 31, 2023 | Wolves | 105 | Spurs | 139 |
| April | 2, 2023 | Heat | 114 | Spurs | 119 |
| April | 4, 2023 | Spurs | 144 | Pelicans | 137 |
| April | 7, 2023 | Pelicans | 111 | Spurs | 122 |
| April | 11, 2023 | Celtics | 106 | Spurs | 114 |
| April | 14, 2023 | Spurs | 86 | Bucks | 106 |
| April | 15, 2023 | Nuggets | 103 | Spurs | 134 |
| April | 19, 2023 | Spurs | 116 | Warriors | 118 |
| April | 21, 2023 | Lakers | 90 | Spurs | 135 |
| April | 22, 2023 | Spurs | 119 | Mavericks | 116 |
| April | 24, 2023 | Clippers | 130 | Spurs | 134 |
| April | 26, 2023 | Spurs | 130 | Bulls | 107 |
| April | 27, 2023 | 76ers | 98 | Spurs | 123 |
| April | 30, 2023 | Spurs | 132 | Trailblazers | 87 |
| May | 1, 2023 | Spurs | 105 | Rockets | 114 |
| Post | 1, 2023 | Spurs | 103 | Warriors | 111 |
| Post | 2, 2023 | Spurs | 117 | Warriors | 128 |
| Post | 3, 2023 | Warriors | 95 | Spurs | 118 |
| Post | 4, 2023 | Warriors | 117 | Spurs | 116 |
| Post | 5, 2023 | Spurs | 134 | Warriors | 109 |
| Post | 6, 2023 | Warriors | 129 | Spurs | 116 |
| Post | 7, 2023 | Spurs | | Warriors | |