| month | day | visitor | score | home | score |
|---|
| November | 4, 2021 | Mavericks | 88 | Suns | 100 |
| November | 7, 2021 | Suns | 105 | Nuggets | 121 |
| November | 9, 2021 | Suns | 118 | Warriors | 103 |
| November | 12, 2021 | Lakers | 124 | Suns | 116 |
| November | 16, 2021 | Suns | 109 | Grizzlies | 107 |
| November | 17, 2021 | Suns | 90 | Thunder | 123 |
| November | 20, 2021 | Spurs | 109 | Suns | 95 |
| November | 22, 2021 | Raptors | 105 | Suns | 89 |
| November | 24, 2021 | Grizzlies | 101 | Suns | 109 |
| November | 26, 2021 | Nets | 90 | Suns | 89 |
| November | 28, 2021 | Celtics | 116 | Suns | 109 |
| November | 30, 2021 | Suns | 91 | Pelicans | 95 |
| December | 2, 2021 | Suns | 97 | Thunder | 116 |
| December | 4, 2021 | Spurs | 115 | Suns | 124 |
| December | 7, 2021 | Thunder | 112 | Suns | 122 |
| December | 9, 2021 | Suns | 97 | 76ers | 139 |
| December | 12, 2021 | Suns | 111 | Bulls | 123 |
| December | 14, 2021 | Suns | 109 | Bucks | 111 |
| December | 16, 2021 | Suns | 94 | Pistons | 123 |
| December | 18, 2021 | Pacers | 132 | Suns | 122 |
| December | 19, 2021 | Suns | 107 | Clippers | 135 |
| December | 21, 2021 | Magic | 141 | Suns | 124 |
| December | 23, 2021 | Suns | 124 | Lakers | 100 |
| December | 26, 2021 | Kings | 99 | Suns | 131 |
| December | 28, 2021 | Suns | 84 | Trailblazers | 110 |
| December | 29, 2021 | Heat | 102 | Suns | 93 |
| January | 1, 2022 | Clippers | 109 | Suns | 118 |
| January | 2, 2022 | Suns | 113 | Spurs | 129 |
| January | 4, 2022 | Mavericks | 119 | Suns | 94 |
| January | 6, 2022 | Wolves | 90 | Suns | 98 |
| January | 8, 2022 | Suns | 94 | Knicks | 90 |
| January | 10, 2022 | Suns | 87 | Celtics | 106 |
| January | 13, 2022 | Suns | 67 | Wizards | 114 |
| January | 14, 2022 | Suns | 90 | Nets | 97 |
| January | 16, 2022 | Suns | 108 | Magic | 121 |
| January | 18, 2022 | Thunder | 100 | Suns | 105 |
| January | 19, 2022 | Nuggets | 103 | Suns | 94 |
| January | 21, 2022 | Warriors | 123 | Suns | 95 |
| January | 23, 2022 | 76ers | 82 | Suns | 86 |
| January | 25, 2022 | Clippers | 113 | Suns | 120 |
| January | 27, 2022 | Hornets | 83 | Suns | 91 |
| January | 29, 2022 | Kings | 108 | Suns | 122 |
| January | 30, 2022 | Suns | 101 | Mavericks | 98 |
| February | 2, 2022 | Nuggets | 103 | Suns | 116 |
| February | 6, 2022 | Suns | 86 | Pacers | 113 |
| February | 13, 2022 | Suns | 87 | Raptors | 127 |
| February | 15, 2022 | Suns | 86 | Hornets | 100 |
| February | 16, 2022 | Suns | 87 | Wolves | 101 |
| February | 18, 2022 | Wolves | 106 | Suns | 75 |
| February | 20, 2022 | Trailblazers | 104 | Suns | 82 |
| February | 21, 2022 | Suns | 104 | Nuggets | 123 |
| February | 23, 2022 | Suns | 124 | Lakers | 126 |
| February | 25, 2022 | Suns | 99 | Spurs | 114 |
| March | 2, 2022 | Hawks | 87 | Suns | 84 |
| March | 4, 2022 | Rockets | 83 | Suns | 85 |
| March | 6, 2022 | Suns | 102 | Jazz | 117 |
| March | 8, 2022 | Warriors | 118 | Suns | 120 |
| March | 10, 2022 | Suns | 96 | Kings | 127 |
| March | 13, 2022 | Suns | 98 | Clippers | 115 |
| March | 15, 2022 | Suns | 92 | Cavaliers | 111 |
| March | 17, 2022 | Suns | 81 | Hawks | 97 |
| March | 19, 2022 | Suns | 88 | Heat | 115 |
| March | 23, 2022 | Pelicans | 114 | Suns | 84 |
| March | 24, 2022 | Lakers | 115 | Suns | 131 |
| March | 26, 2022 | Bucks | 105 | Suns | 104 |
| March | 28, 2022 | Knicks | 88 | Suns | 85 |
| March | 31, 2022 | Suns | 77 | Trailblazers | 94 |
| April | 1, 2022 | Suns | 89 | Warriors | 87 |
| April | 4, 2022 | Jazz | 117 | Suns | 106 |
| April | 6, 2022 | Suns | 101 | Rockets | 99 |
| April | 7, 2022 | Suns | 96 | Pelicans | 100 |
| April | 9, 2022 | Bulls | 102 | Suns | 71 |
| April | 12, 2022 | Pistons | 109 | Suns | 75 |
| April | 14, 2022 | Suns | 113 | Kings | 128 |
| April | 16, 2022 | Suns | 101 | Jazz | 137 |
| April | 18, 2022 | Wizards | 116 | Suns | 105 |
| April | 21, 2022 | Grizzlies | 109 | Suns | 95 |
| April | 23, 2022 | Cavaliers | 86 | Suns | 97 |
| April | 25, 2022 | Jazz | 102 | Suns | 93 |
| April | 27, 2022 | Pelicans | 105 | Suns | 121 |
| April | 29, 2022 | Suns | 113 | Rockets | 99 |
| April | 30, 2022 | Suns | 105 | Mavericks | 99 |