| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Wolves | 101 | Thunder | 124 |
| November | 5, 2020 | Clippers | 109 | Thunder | 132 |
| November | 7, 2020 | Thunder | 114 | Lakers | 122 |
| November | 8, 2020 | Thunder | 99 | Rockets | 94 |
| November | 9, 2020 | Nuggets | 105 | Thunder | 132 |
| November | 12, 2020 | Spurs | 106 | Thunder | 99 |
| November | 15, 2020 | Thunder | 110 | Raptors | 114 |
| November | 18, 2020 | Thunder | 117 | Bucks | 126 |
| November | 20, 2020 | Thunder | 113 | Bulls | 105 |
| November | 23, 2020 | Thunder | 111 | Magic | 114 |
| November | 25, 2020 | Thunder | 117 | Cavaliers | 123 |
| November | 28, 2020 | Thunder | 114 | Trailblazers | 122 |
| November | 30, 2020 | Nets | 107 | Thunder | 111 |
| December | 1, 2020 | Pistons | 113 | Thunder | 134 |
| December | 3, 2020 | Thunder | 99 | Warriors | 103 |
| December | 6, 2020 | Hornets | 107 | Thunder | 100 |
| December | 9, 2020 | Raptors | 106 | Thunder | 102 |
| December | 12, 2020 | Thunder | 110 | 76ers | 125 |
| December | 14, 2020 | Thunder | 120 | Celtics | 119 |
| December | 17, 2020 | Wizards | 94 | Thunder | 133 |
| December | 18, 2020 | Hawks | 124 | Thunder | 118 |
| December | 20, 2020 | Thunder | 104 | Pelicans | 117 |
| December | 22, 2020 | Lakers | 110 | Thunder | 120 |
| December | 25, 2020 | Warriors | 110 | Thunder | 106 |
| December | 27, 2020 | Jazz | 112 | Thunder | 106 |
| December | 29, 2020 | Thunder | 109 | Grizzlies | 119 |
| December | 31, 2020 | Mavericks | 112 | Thunder | 105 |
| January | 2, 2021 | Thunder | 101 | Suns | 125 |
| January | 4, 2021 | Celtics | 132 | Thunder | 144 |
| January | 6, 2021 | Thunder | 110 | Clippers | 117 |
| January | 8, 2021 | Rockets | 124 | Thunder | 103 |
| January | 10, 2021 | Thunder | 105 | Pelicans | 103 |
| January | 12, 2021 | 76ers | 130 | Thunder | 98 |
| January | 15, 2021 | Heat | 119 | Thunder | 117 |
| January | 16, 2021 | Pacers | 93 | Thunder | 141 |
| January | 19, 2021 | Thunder | 112 | Jazz | 127 |
| January | 20, 2021 | Thunder | 117 | Spurs | 140 |
| January | 23, 2021 | Magic | 140 | Thunder | 125 |
| January | 25, 2021 | Thunder | 108 | Mavericks | 102 |
| January | 28, 2021 | Suns | 98 | Thunder | 113 |
| January | 30, 2021 | Thunder | 103 | Pacers | 117 |
| February | 2, 2021 | Wolves | 109 | Thunder | 112 |
| February | 5, 2021 | Thunder | 133 | Knicks | 121 |
| February | 7, 2021 | Thunder | 118 | Nets | 88 |
| February | 14, 2021 | Thunder | 124 | Nuggets | 110 |
| February | 16, 2021 | Bucks | 86 | Thunder | 106 |
| February | 19, 2021 | Thunder | 108 | Hornets | 119 |
| February | 22, 2021 | Jazz | 107 | Thunder | 102 |
| February | 25, 2021 | Thunder | 102 | Clippers | 99 |
| February | 28, 2021 | Grizzlies | 110 | Thunder | 112 |
| March | 2, 2021 | Thunder | 103 | Wizards | 117 |
| March | 4, 2021 | Thunder | 118 | Heat | 104 |
| March | 5, 2021 | Thunder | 92 | Pistons | 116 |
| March | 7, 2021 | Lakers | 118 | Thunder | 121 |
| March | 10, 2021 | Mavericks | 109 | Thunder | 112 |
| March | 12, 2021 | Thunder | 101 | Hawks | 116 |
| March | 15, 2021 | Thunder | 96 | Rockets | 125 |
| March | 18, 2021 | Thunder | 131 | Spurs | 146 |
| March | 21, 2021 | Pelicans | 122 | Thunder | 110 |
| March | 22, 2021 | Thunder | 99 | Wolves | 131 |
| March | 24, 2021 | Clippers | 132 | Thunder | 127 |
| March | 27, 2021 | Cavaliers | 127 | Thunder | 89 |
| March | 29, 2021 | Thunder | 87 | Kings | 106 |
| March | 31, 2021 | Thunder | 123 | Nuggets | 125 |
| April | 3, 2021 | Kings | 96 | Thunder | 108 |
| April | 4, 2021 | Thunder | 106 | Lakers | 132 |
| April | 6, 2021 | Thunder | 103 | Mavericks | 111 |
| April | 9, 2021 | Trailblazers | 111 | Thunder | 109 |
| April | 11, 2021 | Bulls | 109 | Thunder | 112 |
| April | 13, 2021 | Nuggets | 113 | Thunder | 135 |
| April | 14, 2021 | Pelicans | 123 | Thunder | 115 |
| April | 16, 2021 | Kings | 90 | Thunder | 107 |
| April | 18, 2021 | Rockets | 113 | Thunder | 98 |
| April | 19, 2021 | Thunder | 125 | Trailblazers | 133 |
| April | 21, 2021 | Thunder | 88 | Kings | 99 |
| April | 22, 2021 | Suns | 101 | Thunder | 114 |
| April | 24, 2021 | Thunder | 127 | Wolves | 107 |
| April | 25, 2021 | Thunder | 103 | Jazz | 137 |
| April | 27, 2021 | Knicks | 121 | Thunder | 119 |
| April | 28, 2021 | Grizzlies | 123 | Thunder | 113 |
| April | 30, 2021 | Warriors | 114 | Thunder | 121 |
| May | 1, 2021 | Thunder | 102 | Suns | 115 |