| month | day | visitor | score | home | score |
|---|
| November | 3, 2024 | Nets | 133 | Pistons | 101 |
| November | 5, 2024 | Pistons | 125 | Bucks | 140 |
| November | 7, 2024 | Hawks | 118 | Pistons | 94 |
| November | 8, 2024 | Mavericks | 137 | Pistons | 110 |
| November | 11, 2024 | Celtics | 87 | Pistons | 114 |
| November | 12, 2024 | 76ers | 126 | Pistons | 125 |
| November | 15, 2024 | Pelicans | 114 | Pistons | 127 |
| November | 16, 2024 | Magic | 121 | Pistons | 117 |
| November | 17, 2024 | Pistons | 125 | Jazz | 117 |
| November | 19, 2024 | Pistons | 120 | Raptors | 132 |
| November | 21, 2024 | Grizzlies | 102 | Pistons | 114 |
| November | 23, 2024 | Pistons | 74 | Hawks | 94 |
| November | 26, 2024 | Pistons | 108 | Knicks | 118 |
| November | 28, 2024 | Suns | 110 | Pistons | 116 |
| December | 1, 2024 | Pistons | | Thunder | |
| December | 2, 2024 | Wizards | | Pistons | |
| December | 5, 2024 | Pistons | | Pacers | |
| December | 6, 2024 | Warriors | | Pistons | |
| December | 7, 2024 | Pistons | | Lakers | |
| December | 10, 2024 | Raptors | | Pistons | |
| December | 12, 2024 | Pistons | | Hornets | |
| December | 15, 2024 | Bucks | | Pistons | |
| December | 16, 2024 | Pistons | | Spurs | |
| December | 19, 2024 | Pistons | | Bulls | |
| December | 22, 2024 | Nets | | Pistons | |
| December | 26, 2024 | Pacers | | Pistons | |
| December | 27, 2024 | Kings | | Pistons | |
| December | 29, 2024 | Rockets | | Pistons | |
| December | 30, 2024 | Bulls | | Pistons | |
| January | 2, 2025 | Bucks | | Pistons | |
| January | 3, 2025 | Pistons | | Grizzlies | |
| January | 5, 2025 | Pistons | | Heat | |
| January | 6, 2025 | Wolves | | Pistons | |
| January | 8, 2025 | Hawks | | Pistons | |
| January | 10, 2025 | Hornets | | Pistons | |
| January | 12, 2025 | Pistons | | Cavaliers | |
| January | 14, 2025 | Pistons | | Wizards | |
| January | 15, 2025 | Pistons | | Kings | |
| January | 18, 2025 | Trailblazers | | Pistons | |
| January | 20, 2025 | Clippers | | Pistons | |
| January | 23, 2025 | Pistons | | Raptors | |
| January | 26, 2025 | Pistons | | Bucks | |
| January | 29, 2025 | Pistons | | Pelicans | |
| January | 30, 2025 | Bulls | | Pistons | |
| February | 2, 2025 | Raptors | | Pistons | |
| February | 6, 2025 | Wizards | | Pistons | |
| February | 7, 2025 | Magic | | Pistons | |
| February | 11, 2025 | Pistons | | Rockets | |
| February | 15, 2025 | Pistons | | Nuggets | |
| February | 18, 2025 | Lakers | | Pistons | |
| February | 20, 2025 | Pistons | | Knicks | |
| February | 22, 2025 | Heat | | Pistons | |
| February | 24, 2025 | Jazz | | Pistons | |
| February | 27, 2025 | Pistons | | Nets | |
| March | 1, 2025 | Pistons | | 76ers | |
| March | 2, 2025 | Pistons | | Mavericks | |
| March | 5, 2025 | Thunder | | Pistons | |
| March | 7, 2025 | Pistons | | Wolves | |
| March | 8, 2025 | Pistons | | Magic | |
| March | 11, 2025 | Pistons | | Warriors | |
| March | 14, 2025 | Spurs | | Pistons | |
| March | 17, 2025 | Pistons | | Celtics | |
| March | 18, 2025 | Pistons | | Bulls | |
| March | 21, 2025 | Hornets | | Pistons | |
| March | 24, 2025 | Pistons | | Cavaliers | |
| March | 25, 2025 | Pistons | | 76ers | |
| March | 28, 2025 | Pistons | | Nets | |
| March | 31, 2025 | Pistons | | Magic | |
| April | 5, 2025 | Pistons | | Clippers | |
| April | 7, 2025 | Knicks | | Pistons | |
| April | 8, 2025 | Pistons | | Wizards | |
| April | 11, 2025 | Pistons | | Heat | |
| April | 13, 2025 | Pistons | | Pacers | |
| April | 15, 2025 | Knicks | | Pistons | |
| April | 17, 2025 | Cavaliers | | Pistons | |
| April | 18, 2025 | Celtics | | Pistons | |
| April | 20, 2025 | Pistons | | Suns | |
| April | 21, 2025 | Heat | | Pistons | |
| April | 24, 2025 | Nuggets | | Pistons | |
| April | 27, 2025 | Pistons | | Hornets | |
| April | 30, 2025 | 76ers | | Pistons | |
| May | 1, 2025 | Pistons | | Trailblazers | |