| month | day | visitor | score | home | score |
|---|
| November | 2, 2024 | Pistons | 107 | Bucks | 105 |
| November | 3, 2024 | Pistons | 88 | Spurs | 135 |
| November | 5, 2024 | Warriors | 118 | Pistons | 123 |
| November | 6, 2024 | Wizards | 108 | Pistons | 96 |
| November | 8, 2024 | Wolves | 123 | Pistons | 129 |
| November | 9, 2024 | Pacers | 140 | Pistons | 119 |
| November | 11, 2024 | Pistons | 103 | Nets | 147 |
| November | 12, 2024 | 76ers | 111 | Pistons | 127 |
| November | 15, 2024 | Pistons | 97 | Raptors | 130 |
| November | 17, 2024 | Heat | 125 | Pistons | 102 |
| November | 21, 2024 | Pistons | 112 | Nuggets | 121 |
| November | 24, 2024 | Wizards | 115 | Pistons | 102 |
| November | 26, 2024 | Pistons | 106 | Rockets | 126 |
| November | 28, 2024 | Celtics | 116 | Pistons | 102 |
| November | 30, 2024 | Heat | 117 | Pistons | 103 |
| December | 3, 2024 | Pistons | 110 | Heat | 119 |
| December | 4, 2024 | Raptors | 133 | Pistons | 117 |
| December | 7, 2024 | Pistons | 115 | Bulls | 107 |
| December | 8, 2024 | Pistons | 108 | Kings | 135 |
| December | 12, 2024 | Bucks | 112 | Pistons | 128 |
| December | 15, 2024 | Spurs | 124 | Pistons | 96 |
| December | 17, 2024 | Nets | 132 | Pistons | 135 |
| December | 19, 2024 | Pistons | 129 | Trailblazers | 155 |
| December | 20, 2024 | Pistons | 101 | Bulls | 115 |
| December | 22, 2024 | Pistons | 118 | Hornets | 114 |
| December | 27, 2024 | Pistons | 114 | Bucks | 123 |
| December | 28, 2024 | Pistons | 121 | 76ers | 116 |
| December | 31, 2024 | Pistons | 115 | Celtics | 122 |
| January | 2, 2025 | Nets | 134 | Pistons | 118 |
| January | 3, 2025 | Pistons | 77 | Cavaliers | 121 |
| January | 5, 2025 | Pistons | 118 | Magic | 139 |
| January | 6, 2025 | Pistons | 97 | Thunder | 139 |
| January | 8, 2025 | Pistons | 121 | Wizards | 129 |
| January | 10, 2025 | Pistons | 114 | Knicks | 136 |
| January | 11, 2025 | Grizzlies | 108 | Pistons | 122 |
| January | 14, 2025 | Mavericks | 104 | Pistons | 117 |
| January | 16, 2025 | Clippers | 130 | Pistons | 124 |
| January | 17, 2025 | Magic | 123 | Pistons | 115 |
| January | 19, 2025 | Lakers | 134 | Pistons | 154 |
| January | 23, 2025 | Hawks | 104 | Pistons | 97 |
| January | 27, 2025 | Suns | 131 | Pistons | 147 |
| January | 29, 2025 | Bucks | 136 | Pistons | 128 |
| January | 31, 2025 | Pistons | 116 | 76ers | 119 |
| February | 2, 2025 | Pelicans | 127 | Pistons | 99 |
| February | 6, 2025 | Knicks | 98 | Pistons | 134 |
| February | 11, 2025 | Pistons | 111 | Hawks | 116 |
| February | 12, 2025 | Pistons | 137 | Raptors | 146 |
| February | 14, 2025 | Trailblazers | 128 | Pistons | 118 |
| February | 18, 2025 | Bulls | 115 | Pistons | 113 |
| February | 22, 2025 | Pistons | 130 | Knicks | 122 |
| February | 25, 2025 | Pistons | 115 | Wolves | 124 |
| February | 26, 2025 | Pistons | 90 | Magic | 141 |
| March | 3, 2025 | Hawks | 125 | Pistons | 115 |
| March | 4, 2025 | Pistons | 119 | Celtics | 132 |
| March | 9, 2025 | Pistons | 96 | Jazz | 121 |
| March | 11, 2025 | Kings | 95 | Pistons | 114 |
| March | 13, 2025 | Knicks | 118 | Pistons | 108 |
| March | 14, 2025 | 76ers | 111 | Pistons | 117 |
| March | 16, 2025 | Pistons | 105 | Hornets | 119 |
| March | 17, 2025 | Pistons | 110 | Nets | 126 |
| March | 20, 2025 | Cavaliers | 119 | Pistons | 111 |
| March | 21, 2025 | Pistons | 107 | Mavericks | 132 |
| March | 24, 2025 | Thunder | 113 | Pistons | 111 |
| March | 26, 2025 | Hornets | 127 | Pistons | 126 |
| March | 28, 2025 | Jazz | 116 | Pistons | 119 |
| March | 30, 2025 | Cavaliers | 136 | Pistons | 106 |
| April | 1, 2025 | Bulls | 113 | Pistons | 140 |
| April | 2, 2025 | Pacers | 110 | Pistons | 119 |
| April | 5, 2025 | Pistons | 103 | Wizards | 120 |
| April | 6, 2025 | Pistons | 105 | Suns | 130 |
| April | 10, 2025 | Pistons | 115 | Lakers | 124 |
| April | 14, 2025 | Pistons | 120 | Grizzlies | 119 |
| April | 16, 2025 | Pistons | 134 | Heat | 119 |
| April | 17, 2025 | Pistons | 110 | Pelicans | 134 |
| April | 20, 2025 | Magic | 115 | Pistons | 110 |
| April | 21, 2025 | Pistons | 110 | Clippers | 118 |
| April | 24, 2025 | Pistons | 137 | Pacers | 133 |
| April | 25, 2025 | Nuggets | 115 | Pistons | 97 |
| April | 27, 2025 | Rockets | 101 | Pistons | 125 |
| April | 28, 2025 | Pistons | 93 | Warriors | 123 |
| April | 30, 2025 | Pistons | 92 | Cavaliers | 106 |
| May | 1, 2025 | Celtics | 127 | Pistons | 123 |