| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Suns | 128 | Grizzlies | 108 |
| November | 4, 2022 | Grizzlies | 106 | Nuggets | 103 |
| November | 7, 2022 | Wolves | 101 | Grizzlies | 107 |
| November | 9, 2022 | Grizzlies | 87 | Kings | 99 |
| November | 10, 2022 | Grizzlies | 105 | Hornets | 106 |
| November | 12, 2022 | Heat | 95 | Grizzlies | 113 |
| November | 14, 2022 | Grizzlies | 105 | Bulls | 114 |
| November | 15, 2022 | Grizzlies | 103 | Bucks | 93 |
| November | 18, 2022 | Grizzlies | 85 | Hawks | 98 |
| November | 21, 2022 | Grizzlies | 89 | Pistons | 96 |
| November | 24, 2022 | Clippers | 98 | Grizzlies | 93 |
| November | 25, 2022 | Mavericks | 97 | Grizzlies | 120 |
| November | 28, 2022 | Grizzlies | 89 | Rockets | 120 |
| November | 30, 2022 | 76ers | 97 | Grizzlies | 107 |
| December | 2, 2022 | Grizzlies | 90 | Trailblazers | 103 |
| December | 4, 2022 | Nets | 90 | Grizzlies | 89 |
| December | 5, 2022 | Jazz | 108 | Grizzlies | 114 |
| December | 8, 2022 | Grizzlies | 89 | Warriors | 100 |
| December | 10, 2022 | Grizzlies | 84 | Lakers | 97 |
| December | 12, 2022 | Celtics | 100 | Grizzlies | 131 |
| December | 15, 2022 | Grizzlies | 127 | 76ers | 97 |
| December | 17, 2022 | Grizzlies | 84 | Cavaliers | 91 |
| December | 20, 2022 | Grizzlies | 95 | Wizards | 100 |
| December | 22, 2022 | Magic | 95 | Grizzlies | 100 |
| December | 26, 2022 | Grizzlies | 78 | Mavericks | 104 |
| December | 29, 2022 | Thunder | 95 | Grizzlies | 82 |
| January | 1, 2023 | Grizzlies | 91 | Wolves | 101 |
| January | 3, 2023 | Pistons | 89 | Grizzlies | 88 |
| January | 4, 2023 | Warriors | 99 | Grizzlies | 80 |
| January | 7, 2023 | Pelicans | 94 | Grizzlies | 101 |
| January | 8, 2023 | Grizzlies | 112 | Spurs | 130 |
| January | 10, 2023 | Bucks | 89 | Grizzlies | 85 |
| January | 13, 2023 | Grizzlies | 86 | Nets | 93 |
| January | 16, 2023 | Grizzlies | 104 | Heat | 102 |
| January | 18, 2023 | Raptors | 103 | Grizzlies | 89 |
| January | 21, 2023 | Grizzlies | 97 | Jazz | 92 |
| January | 23, 2023 | Cavaliers | 79 | Grizzlies | 119 |
| January | 25, 2023 | Grizzlies | 113 | Suns | 108 |
| January | 28, 2023 | Grizzlies | 112 | Knicks | 119 |
| January | 30, 2023 | Grizzlies | 91 | Raptors | 107 |
| January | 31, 2023 | Lakers | 119 | Grizzlies | 106 |
| February | 4, 2023 | Suns | 114 | Grizzlies | 98 |
| February | 6, 2023 | Nuggets | 97 | Grizzlies | 106 |
| February | 13, 2023 | Grizzlies | 84 | Clippers | 92 |
| February | 15, 2023 | Grizzlies | 89 | Warriors | 106 |
| February | 17, 2023 | Grizzlies | 111 | Pelicans | 103 |
| February | 18, 2023 | Nuggets | 98 | Grizzlies | 105 |
| February | 21, 2023 | Rockets | 103 | Grizzlies | 101 |
| February | 24, 2023 | Bulls | 106 | Grizzlies | 112 |
| February | 27, 2023 | Grizzlies | 90 | Jazz | 96 |
| February | 28, 2023 | Grizzlies | 129 | Thunder | 145 |
| March | 2, 2023 | Jazz | 85 | Grizzlies | 110 |
| March | 4, 2023 | Grizzlies | 82 | Trailblazers | 97 |
| March | 7, 2023 | Hornets | 93 | Grizzlies | 89 |
| March | 10, 2023 | Knicks | 109 | Grizzlies | 97 |
| March | 12, 2023 | Grizzlies | 118 | Spurs | 109 |
| March | 14, 2023 | Wizards | 104 | Grizzlies | 96 |
| March | 16, 2023 | Warriors | 107 | Grizzlies | 111 |
| March | 19, 2023 | Pelicans | 81 | Grizzlies | 93 |
| March | 21, 2023 | Grizzlies | 113 | Mavericks | 106 |
| March | 24, 2023 | Hawks | 94 | Grizzlies | 122 |
| March | 27, 2023 | Grizzlies | 78 | Clippers | 109 |
| March | 29, 2023 | Trailblazers | 99 | Grizzlies | 116 |
| March | 31, 2023 | Kings | 107 | Grizzlies | 100 |
| April | 2, 2023 | Grizzlies | 76 | Magic | 91 |
| April | 4, 2023 | Grizzlies | 92 | Celtics | 111 |
| April | 5, 2023 | Grizzlies | 91 | Pacers | 100 |
| April | 7, 2023 | Wolves | 96 | Grizzlies | 91 |
| April | 8, 2023 | Grizzlies | 99 | Pelicans | 77 |
| April | 10, 2023 | Pacers | 101 | Grizzlies | 94 |
| April | 13, 2023 | Grizzlies | 103 | Wolves | 110 |
| April | 14, 2023 | Grizzlies | 72 | Lakers | 88 |
| April | 16, 2023 | Clippers | 101 | Grizzlies | 93 |
| April | 17, 2023 | Trailblazers | 95 | Grizzlies | 87 |
| April | 19, 2023 | Grizzlies | 94 | Kings | 99 |
| April | 21, 2023 | Spurs | 125 | Grizzlies | 95 |
| April | 23, 2023 | Rockets | 88 | Grizzlies | 81 |
| April | 25, 2023 | Grizzlies | 85 | Nuggets | 98 |
| April | 26, 2023 | Mavericks | 92 | Grizzlies | 103 |
| April | 28, 2023 | Grizzlies | 92 | Thunder | 97 |
| April | 30, 2023 | Spurs | 76 | Grizzlies | 93 |
| May | 1, 2023 | Kings | 101 | Grizzlies | 107 |