| month | day | visitor | score | home | score |
|---|
| November | 3, 2021 | Bucks | 97 | Hornets | 119 |
| November | 6, 2021 | Pacers | 97 | Bucks | 95 |
| November | 9, 2021 | Knicks | 109 | Bucks | 123 |
| November | 12, 2021 | 76ers | 96 | Bucks | 117 |
| November | 14, 2021 | Bucks | 105 | Wolves | 80 |
| November | 16, 2021 | Magic | 103 | Bucks | 115 |
| November | 18, 2021 | Raptors | 111 | Bucks | 115 |
| November | 21, 2021 | Bucks | 117 | Celtics | 87 |
| November | 24, 2021 | Kings | 81 | Bucks | 114 |
| November | 26, 2021 | Bucks | 110 | Trailblazers | 118 |
| November | 28, 2021 | Bucks | 119 | Warriors | 129 |
| November | 30, 2021 | Bucks | 102 | Clippers | 123 |
| December | 1, 2021 | Bucks | 114 | Nuggets | 100 |
| December | 4, 2021 | Grizzlies | 127 | Bucks | 121 |
| December | 6, 2021 | Bulls | 96 | Bucks | 114 |
| December | 9, 2021 | Nuggets | 111 | Bucks | 112 |
| December | 11, 2021 | Trailblazers | 95 | Bucks | 118 |
| December | 14, 2021 | Suns | 109 | Bucks | 111 |
| December | 15, 2021 | Spurs | 94 | Bucks | 121 |
| December | 17, 2021 | Bucks | 119 | Hornets | 114 |
| December | 19, 2021 | Bulls | 116 | Bucks | 118 |
| December | 22, 2021 | Bucks | 112 | Knicks | 98 |
| December | 27, 2021 | Pistons | 111 | Bucks | 103 |
| December | 29, 2021 | Warriors | 119 | Bucks | 122 |
| December | 31, 2021 | Bucks | 102 | Raptors | 118 |
| January | 1, 2022 | Cavaliers | 107 | Bucks | 121 |
| January | 3, 2022 | Bucks | 117 | Pacers | 130 |
| January | 5, 2022 | Bucks | 135 | Cavaliers | 117 |
| January | 8, 2022 | Bucks | 103 | Pistons | 117 |
| January | 10, 2022 | Pelicans | 103 | Bucks | 105 |
| January | 12, 2022 | Bucks | 107 | Celtics | 114 |
| January | 13, 2022 | Bucks | 108 | Heat | 114 |
| January | 15, 2022 | Bucks | 112 | Knicks | 98 |
| January | 17, 2022 | Knicks | 103 | Bucks | 122 |
| January | 19, 2022 | Nets | 91 | Bucks | 112 |
| January | 22, 2022 | Pistons | 117 | Bucks | 102 |
| January | 25, 2022 | Hawks | 98 | Bucks | 102 |
| January | 26, 2022 | Raptors | 127 | Bucks | 139 |
| January | 28, 2022 | Jazz | 106 | Bucks | 103 |
| January | 30, 2022 | Bucks | 103 | Rockets | 121 |
| February | 1, 2022 | Bucks | 104 | Wizards | 121 |
| February | 4, 2022 | Bucks | 119 | Hawks | 116 |
| February | 6, 2022 | Heat | 108 | Bucks | 117 |
| February | 7, 2022 | Bucks | 101 | Grizzlies | 102 |
| February | 15, 2022 | Bucks | 103 | Magic | 118 |
| February | 17, 2022 | Mavericks | 110 | Bucks | 114 |
| February | 21, 2022 | Hornets | 101 | Bucks | 129 |
| February | 23, 2022 | Bucks | 132 | Thunder | 91 |
| February | 25, 2022 | Bucks | 115 | Pistons | 125 |
| February | 27, 2022 | Bucks | 110 | Raptors | 118 |
| March | 1, 2022 | Bucks | 90 | Wizards | 104 |
| March | 4, 2022 | Bucks | 82 | Nets | 76 |
| March | 6, 2022 | Wizards | 104 | Bucks | 121 |
| March | 8, 2022 | Bucks | 91 | Mavericks | 114 |
| March | 9, 2022 | Magic | 117 | Bucks | 121 |
| March | 11, 2022 | Bucks | 119 | Bulls | 113 |
| March | 13, 2022 | Bucks | 110 | Pacers | 125 |
| March | 15, 2022 | Celtics | 102 | Bucks | 123 |
| March | 17, 2022 | Wolves | 95 | Bucks | 103 |
| March | 19, 2022 | Bucks | 143 | Bulls | 138 |
| March | 21, 2022 | Bucks | 122 | Kings | 100 |
| March | 23, 2022 | Bucks | 127 | Lakers | 111 |
| March | 24, 2022 | Bucks | 108 | Jazz | 107 |
| March | 26, 2022 | Bucks | 105 | Suns | 104 |
| March | 29, 2022 | Pacers | 96 | Bucks | 106 |
| March | 31, 2022 | Hornets | 113 | Bucks | 127 |
| April | 1, 2022 | Bucks | 102 | Spurs | 114 |
| April | 3, 2022 | Bucks | 121 | Pelicans | 104 |
| April | 6, 2022 | Bucks | 125 | Heat | 107 |
| April | 8, 2022 | 76ers | 91 | Bucks | 123 |
| April | 10, 2022 | Lakers | 107 | Bucks | 143 |
| April | 11, 2022 | Bucks | 106 | Cavaliers | 115 |
| April | 13, 2022 | Heat | 82 | Bucks | 114 |
| April | 15, 2022 | Cavaliers | 104 | Bucks | 121 |
| April | 17, 2022 | Rockets | 108 | Bucks | 141 |
| April | 19, 2022 | Clippers | 111 | Bucks | 114 |
| April | 22, 2022 | Bucks | 92 | Hawks | 132 |
| April | 23, 2022 | Bucks | 89 | Nets | 92 |
| April | 26, 2022 | Bucks | 124 | 76ers | 109 |
| April | 28, 2022 | Nets | 78 | Bucks | 111 |
| April | 29, 2022 | Hawks | 102 | Bucks | 109 |
| May | 1, 2022 | Thunder | 122 | Bucks | 147 |
| Post | 1, 2022 | Bucks | 117 | Pacers | 111 |
| Post | 2, 2022 | Bucks | 103 | Pacers | 94 |
| Post | 3, 2022 | Pacers | 96 | Bucks | 108 |
| Post | 4, 2022 | Pacers | 88 | Bucks | 109 |
| Post | 5, 2022 | Bucks | | Pacers | |
| Post | 6, 2022 | Pacers | | Bucks | |
| Post | 7, 2022 | Bucks | | Pacers | |
| Post | 8, 2022 | Bucks | 103 | Pistons | 111 |
| Post | 9, 2022 | Bucks | 100 | Pistons | 110 |
| Post | 10, 2022 | Pistons | 111 | Bucks | 113 |
| Post | 11, 2022 | Pistons | 95 | Bucks | 110 |
| Post | 12, 2022 | Bucks | 90 | Pistons | 111 |
| Post | 13, 2022 | Pistons | 121 | Bucks | 125 |
| Post | 14, 2022 | Bucks | 101 | Pistons | 93 |
| Post | 15, 2022 | Bulls | 100 | Bucks | 127 |
| Post | 16, 2022 | Bulls | 115 | Bucks | 122 |
| Post | 17, 2022 | Bucks | 89 | Bulls | 108 |
| Post | 18, 2022 | Bucks | 109 | Bulls | 112 |
| Post | 19, 2022 | Bulls | 95 | Bucks | 111 |
| Post | 20, 2022 | Bucks | 99 | Bulls | 115 |
| Post | 21, 2022 | Bulls | 111 | Bucks | 92 |