| month | day | visitor | score | home | score |
|---|
| November | 2, 2021 | Bucks | 107 | Celtics | 112 |
| November | 3, 2021 | Bucks | 111 | 76ers | 123 |
| November | 5, 2021 | Pistons | 99 | Bucks | 107 |
| November | 8, 2021 | Bucks | 109 | Hornets | 126 |
| November | 10, 2021 | Cavaliers | 100 | Bucks | 112 |
| November | 11, 2021 | Bucks | 108 | Bulls | 100 |
| November | 14, 2021 | Clippers | 96 | Bucks | 122 |
| November | 15, 2021 | Grizzlies | 109 | Bucks | 118 |
| November | 17, 2021 | Rockets | 114 | Bucks | 131 |
| November | 18, 2021 | Thunder | 109 | Bucks | 115 |
| November | 20, 2021 | Bucks | 115 | Cavaliers | 125 |
| November | 21, 2021 | Bucks | 96 | Trailblazers | 110 |
| November | 23, 2021 | Heat | 78 | Bucks | 109 |
| November | 26, 2021 | Bucks | 111 | Nets | 115 |
| November | 28, 2021 | Bulls | 103 | Bucks | 120 |
| November | 30, 2021 | Bucks | 115 | Knicks | 107 |
| December | 2, 2021 | Magic | 108 | Bucks | 109 |
| December | 5, 2021 | Bucks | 117 | Raptors | 110 |
| December | 8, 2021 | Pelicans | 100 | Bucks | 114 |
| December | 9, 2021 | Wizards | 109 | Bucks | 124 |
| December | 12, 2021 | Bucks | 108 | Hawks | 99 |
| December | 15, 2021 | Bucks | 95 | Pistons | 105 |
| December | 18, 2021 | Mavericks | 107 | Bucks | 111 |
| December | 20, 2021 | Bucks | 113 | Pacers | 126 |
| December | 21, 2021 | Nuggets | 100 | Bucks | 127 |
| December | 26, 2021 | Bucks | 110 | Magic | 119 |
| December | 28, 2021 | Bucks | 104 | Spurs | 96 |
| December | 29, 2021 | Bucks | 96 | Warriors | 105 |
| December | 31, 2021 | Kings | 111 | Bucks | 100 |
| January | 2, 2022 | Bucks | 84 | Pistons | 80 |
| January | 4, 2022 | Pacers | 121 | Bucks | 110 |
| January | 7, 2022 | Hornets | 97 | Bucks | 144 |
| January | 10, 2022 | Bucks | 105 | Grizzlies | 104 |
| January | 11, 2022 | Suns | 118 | Bucks | 123 |
| January | 13, 2022 | Spurs | 101 | Bucks | 123 |
| January | 16, 2022 | Hawks | 96 | Bucks | 105 |
| January | 18, 2022 | Bucks | 123 | Bulls | 113 |
| January | 20, 2022 | Lakers | 115 | Bucks | 123 |
| January | 23, 2022 | Bucks | 105 | Rockets | 95 |
| January | 25, 2022 | Jazz | 91 | Bucks | 127 |
| January | 26, 2022 | Pistons | 85 | Bucks | 110 |
| January | 29, 2022 | Bucks | 120 | Clippers | 110 |
| January | 31, 2022 | Pacers | 116 | Bucks | 140 |
| February | 2, 2022 | Bucks | 87 | Heat | 112 |
| February | 4, 2022 | Bucks | 113 | Wizards | 98 |
| February | 13, 2022 | Bucks | 131 | Celtics | 98 |
| February | 16, 2022 | Bucks | 134 | Thunder | 103 |
| February | 18, 2022 | Knicks | 82 | Bucks | 118 |
| February | 19, 2022 | Wolves | 121 | Bucks | 114 |
| February | 22, 2022 | Bucks | 109 | Magic | 114 |
| February | 24, 2022 | Bucks | 126 | Nuggets | 112 |
| February | 25, 2022 | Celtics | 101 | Bucks | 121 |
| February | 27, 2022 | Bucks | 116 | Suns | 94 |
| March | 3, 2022 | Nets | 104 | Bucks | 116 |
| March | 4, 2022 | Bucks | 105 | 76ers | 75 |
| March | 7, 2022 | Bucks | 119 | Cavaliers | 111 |
| March | 9, 2022 | Bucks | 104 | Wolves | 96 |
| March | 12, 2022 | Bucks | 117 | Pelicans | 94 |
| March | 13, 2022 | Bucks | 95 | Kings | 119 |
| March | 15, 2022 | Hawks | 100 | Bucks | 127 |
| March | 18, 2022 | Bucks | 105 | Pacers | 85 |
| March | 21, 2022 | Warriors | 127 | Bucks | 108 |
| March | 22, 2022 | Knicks | 104 | Bucks | 114 |
| March | 24, 2022 | Hornets | 121 | Bucks | 120 |
| March | 25, 2022 | Bucks | 112 | Hawks | 108 |
| March | 28, 2022 | Raptors | 112 | Bucks | 116 |
| March | 31, 2022 | Nets | 51 | Bucks | 75 |
| April | 2, 2022 | Heat | 88 | Bucks | 100 |
| April | 4, 2022 | Bucks | 105 | Knicks | 120 |
| April | 6, 2022 | Celtics | 91 | Bucks | 115 |
| April | 7, 2022 | Bucks | 118 | Jazz | 112 |
| April | 9, 2022 | Magic | 114 | Bucks | 124 |
| April | 11, 2022 | Raptors | 103 | Bucks | 115 |
| April | 14, 2022 | Trailblazers | 76 | Bucks | 105 |
| April | 16, 2022 | Bucks | 120 | Lakers | 103 |
| April | 19, 2022 | Bucks | 97 | Nets | 86 |
| April | 21, 2022 | 76ers | 89 | Bucks | 126 |
| April | 23, 2022 | Bucks | 117 | Mavericks | 104 |
| April | 24, 2022 | Bucks | 100 | Heat | 91 |
| April | 27, 2022 | Wizards | 92 | Bucks | 113 |
| April | 30, 2022 | Cavaliers | 117 | Bucks | 112 |
| May | 1, 2022 | Bucks | 102 | Hornets | 121 |
| Post | 1, 2022 | Hawks | 95 | Bucks | 116 |
| Post | 2, 2022 | Hawks | 82 | Bucks | 115 |
| Post | 3, 2022 | Bucks | 123 | Hawks | 110 |
| Post | 4, 2022 | Bucks | 88 | Hawks | 125 |
| Post | 5, 2022 | Hawks | 100 | Bucks | 119 |
| Post | 6, 2022 | Bucks | | Hawks | |
| Post | 7, 2022 | Hawks | | Bucks | |
| Post | 8, 2022 | Bulls | 102 | Bucks | 117 |
| Post | 9, 2022 | Bulls | 101 | Bucks | 115 |
| Post | 10, 2022 | Bucks | 109 | Bulls | 110 |
| Post | 11, 2022 | Bucks | 123 | Bulls | 112 |
| Post | 12, 2022 | Bulls | 99 | Bucks | 107 |
| Post | 13, 2022 | Bucks | | Bulls | |
| Post | 14, 2022 | Bulls | | Bucks | |
| Post | 15, 2022 | Raptors | 100 | Bucks | 112 |
| Post | 16, 2022 | Raptors | 84 | Bucks | 106 |
| Post | 17, 2022 | Bucks | 101 | Raptors | 122 |
| Post | 18, 2022 | Bucks | 109 | Raptors | 119 |
| Post | 19, 2022 | Raptors | 116 | Bucks | 124 |
| Post | 20, 2022 | Bucks | 115 | Raptors | 103 |
| Post | 21, 2022 | Raptors | | Bucks | |
| Post | 22, 2022 | Warriors | 116 | Bucks | 104 |
| Post | 23, 2022 | Warriors | 115 | Bucks | 100 |
| Post | 24, 2022 | Bucks | 106 | Warriors | 111 |
| Post | 25, 2022 | Bucks | 91 | Warriors | 110 |