| month | day | visitor | score | home | score |
|---|
| November | 2, 2020 | 76ers | 113 | Celtics | 104 |
| November | 6, 2020 | Celtics | 118 | Raptors | 127 |
| November | 7, 2020 | Celtics | 83 | Knicks | 95 |
| November | 9, 2020 | Magic | 117 | Celtics | 119 |
| November | 13, 2020 | Celtics | 102 | Thunder | 124 |
| November | 15, 2020 | Celtics | 95 | Pistons | 128 |
| November | 19, 2020 | Pistons | 122 | Celtics | 104 |
| November | 21, 2020 | Bucks | 129 | Celtics | 117 |
| November | 23, 2020 | Celtics | 119 | Pacers | 109 |
| November | 25, 2020 | Celtics | 99 | Nuggets | 106 |
| November | 28, 2020 | Celtics | 105 | Suns | 120 |
| November | 29, 2020 | Celtics | 84 | Jazz | 116 |
| December | 1, 2020 | Celtics | 101 | Trailblazers | 106 |
| December | 4, 2020 | Bulls | 129 | Celtics | 96 |
| December | 6, 2020 | Raptors | 135 | Celtics | 93 |
| December | 7, 2020 | Jazz | 114 | Celtics | 100 |
| December | 9, 2020 | Celtics | 103 | Hornets | 108 |
| December | 12, 2020 | Knicks | 132 | Celtics | 112 |
| December | 13, 2020 | Celtics | 122 | Hawks | 120 |
| December | 15, 2020 | Celtics | 116 | Mavericks | 106 |
| December | 17, 2020 | Celtics | 134 | Pelicans | 130 |
| December | 21, 2020 | Cavaliers | 102 | Celtics | 106 |
| December | 22, 2020 | Celtics | 98 | Wolves | 125 |
| December | 28, 2020 | Knicks | 115 | Celtics | 124 |
| December | 30, 2020 | Celtics | 97 | Bulls | 131 |
| January | 1, 2021 | Pelicans | 119 | Celtics | 95 |
| January | 3, 2021 | Celtics | 95 | Wizards | 110 |
| January | 5, 2021 | Hawks | 134 | Celtics | 125 |
| January | 6, 2021 | Celtics | 100 | Pistons | 122 |
| January | 10, 2021 | Suns | 128 | Celtics | 117 |
| January | 12, 2021 | Bucks | 132 | Celtics | 121 |
| January | 14, 2021 | Hornets | 128 | Celtics | 104 |
| January | 15, 2021 | 76ers | 123 | Celtics | 127 |
| January | 17, 2021 | Celtics | 99 | Rockets | 112 |
| January | 19, 2021 | Celtics | 102 | Grizzlies | 121 |
| January | 21, 2021 | Celtics | 135 | Spurs | 149 |
| January | 23, 2021 | Wolves | 123 | Celtics | 101 |
| January | 25, 2021 | Mavericks | 113 | Celtics | 108 |
| January | 28, 2021 | Nets | 105 | Celtics | 131 |
| January | 30, 2021 | Pacers | 131 | Celtics | 113 |
| January | 31, 2021 | Celtics | 109 | Heat | 100 |
| February | 2, 2021 | Celtics | 131 | Magic | 137 |
| February | 5, 2021 | Celtics | 108 | Nets | 121 |
| February | 7, 2021 | Raptors | 116 | Celtics | 92 |
| February | 14, 2021 | Grizzlies | 126 | Celtics | 140 |
| February | 15, 2021 | Celtics | 125 | Hawks | 122 |
| February | 17, 2021 | Heat | 98 | Celtics | 134 |
| February | 19, 2021 | Cavaliers | 146 | Celtics | 108 |
| February | 22, 2021 | Warriors | 105 | Celtics | 82 |
| February | 24, 2021 | Nets | 105 | Celtics | 89 |
| February | 26, 2021 | Hornets | 109 | Celtics | 81 |
| February | 28, 2021 | Celtics | 100 | Knicks | 108 |
| March | 3, 2021 | Thunder | 114 | Celtics | 122 |
| March | 5, 2021 | Celtics | 98 | Cavaliers | 107 |
| March | 7, 2021 | Lakers | 130 | Celtics | 114 |
| March | 9, 2021 | Clippers | 101 | Celtics | 100 |
| March | 12, 2021 | Celtics | 94 | 76ers | 115 |
| March | 13, 2021 | Pistons | 122 | Celtics | 115 |
| March | 15, 2021 | Celtics | 127 | Bucks | 138 |
| March | 17, 2021 | Celtics | 95 | Bulls | 116 |
| March | 20, 2021 | Celtics | 108 | Raptors | 114 |
| March | 21, 2021 | Trailblazers | 121 | Celtics | 124 |
| March | 23, 2021 | Wizards | 112 | Celtics | 101 |
| March | 25, 2021 | Rockets | 129 | Celtics | 114 |
| March | 27, 2021 | Celtics | 87 | Warriors | 103 |
| March | 28, 2021 | Celtics | 75 | Kings | 95 |
| March | 31, 2021 | Celtics | 95 | Lakers | 114 |
| April | 2, 2021 | Celtics | 81 | Clippers | 127 |
| April | 5, 2021 | Kings | 96 | Celtics | 70 |
| April | 7, 2021 | Hawks | 105 | Celtics | 72 |
| April | 9, 2021 | Nuggets | 89 | Celtics | 97 |
| April | 11, 2021 | Celtics | 91 | 76ers | 125 |
| April | 14, 2021 | Celtics | 61 | Hornets | 104 |
| April | 15, 2021 | Spurs | 125 | Celtics | 100 |
| April | 17, 2021 | Celtics | 77 | Cavaliers | 108 |
| April | 20, 2021 | Pacers | 117 | Celtics | 91 |
| April | 21, 2021 | Celtics | 88 | Nets | 114 |
| April | 23, 2021 | Heat | 82 | Celtics | 88 |
| April | 25, 2021 | Celtics | 73 | Heat | 84 |
| April | 27, 2021 | Celtics | 105 | Pacers | 122 |
| April | 29, 2021 | Magic | 117 | Celtics | 113 |
| April | 30, 2021 | Celtics | 60 | Wizards | 97 |