| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Hornets | 90 | Knicks | 99 |
| November | 6, 2020 | Knicks | 118 | Nets | 122 |
| November | 8, 2020 | Knicks | 87 | Celtics | 106 |
| November | 12, 2020 | Lakers | 115 | Knicks | 104 |
| November | 13, 2020 | Knicks | 79 | Mavericks | 113 |
| November | 15, 2020 | Knicks | 113 | 76ers | 139 |
| November | 18, 2020 | Cavaliers | 113 | Knicks | 136 |
| November | 19, 2020 | Warriors | 110 | Knicks | 102 |
| November | 22, 2020 | Knicks | 108 | Clippers | 114 |
| November | 24, 2020 | Knicks | 110 | Heat | 107 |
| November | 26, 2020 | Pistons | 111 | Knicks | 105 |
| November | 29, 2020 | Knicks | 102 | Wizards | 117 |
| November | 30, 2020 | Bucks | 116 | Knicks | 91 |
| December | 2, 2020 | Knicks | 99 | Warriors | 109 |
| December | 4, 2020 | Pelicans | 114 | Knicks | 96 |
| December | 6, 2020 | Knicks | 83 | Raptors | 124 |
| December | 8, 2020 | Knicks | 100 | Lakers | 116 |
| December | 9, 2020 | Spurs | 131 | Knicks | 87 |
| December | 11, 2020 | Knicks | 98 | Pelicans | 131 |
| December | 13, 2020 | Knicks | 87 | Kings | 112 |
| December | 15, 2020 | Trailblazers | 134 | Knicks | 124 |
| December | 18, 2020 | Rockets | 99 | Knicks | 94 |
| December | 20, 2020 | Knicks | 77 | Magic | 101 |
| December | 22, 2020 | Hawks | 116 | Knicks | 115 |
| December | 25, 2020 | Nets | 117 | Knicks | 119 |
| December | 27, 2020 | Knicks | 88 | Hornets | 86 |
| December | 29, 2020 | Suns | 111 | Knicks | 119 |
| December | 31, 2020 | Knicks | 105 | Wolves | 108 |
| January | 3, 2021 | Heat | 111 | Knicks | 113 |
| January | 5, 2021 | Knicks | 102 | Pacers | 101 |
| January | 8, 2021 | Jazz | 123 | Knicks | 103 |
| January | 10, 2021 | Knicks | 111 | Hawks | 109 |
| January | 13, 2021 | Knicks | 91 | Suns | 127 |
| January | 15, 2021 | Clippers | 123 | Knicks | 109 |
| January | 17, 2021 | Raptors | 107 | Knicks | 97 |
| January | 21, 2021 | Knicks | 86 | Spurs | 145 |
| January | 23, 2021 | Wolves | 122 | Knicks | 120 |
| January | 24, 2021 | Kings | 93 | Knicks | 110 |
| January | 26, 2021 | Knicks | 111 | Nets | 114 |
| January | 28, 2021 | Grizzlies | 107 | Knicks | 101 |
| January | 31, 2021 | Knicks | 118 | Hawks | 111 |
| February | 2, 2021 | Bulls | 125 | Knicks | 129 |
| February | 4, 2021 | Knicks | 112 | Nuggets | 121 |
| February | 5, 2021 | Thunder | 109 | Knicks | 105 |
| February | 7, 2021 | Knicks | 109 | Pacers | 96 |
| February | 13, 2021 | Knicks | 109 | Raptors | 124 |
| February | 15, 2021 | Celtics | 105 | Knicks | 124 |
| February | 18, 2021 | Knicks | 91 | Bucks | 121 |
| February | 20, 2021 | Pistons | 126 | Knicks | 121 |
| February | 21, 2021 | Knicks | 107 | Bulls | 139 |
| February | 23, 2021 | Knicks | 54 | Rockets | 95 |
| February | 25, 2021 | Magic | 121 | Knicks | 118 |
| February | 27, 2021 | 76ers | 120 | Knicks | 116 |
| March | 1, 2021 | Knicks | 109 | Cavaliers | 127 |
| March | 4, 2021 | Hornets | 99 | Knicks | 65 |
| March | 7, 2021 | Knicks | 109 | Heat | 111 |
| March | 9, 2021 | Nuggets | 112 | Knicks | 102 |
| March | 10, 2021 | Knicks | 109 | Grizzlies | 125 |
| March | 12, 2021 | Knicks | 84 | Magic | 133 |
| March | 14, 2021 | Celtics | 107 | Knicks | 126 |
| March | 17, 2021 | Knicks | 76 | Hornets | 110 |
| March | 20, 2021 | Pacers | 119 | Knicks | 126 |
| March | 22, 2021 | Knicks | 95 | Bucks | 124 |
| March | 24, 2021 | Bulls | 116 | Knicks | 99 |
| March | 25, 2021 | Knicks | 79 | Wizards | 94 |
| March | 27, 2021 | Mavericks | 94 | Knicks | 85 |
| March | 29, 2021 | Cavaliers | 95 | Knicks | 100 |
| March | 31, 2021 | Knicks | 100 | Trailblazers | 117 |
| April | 1, 2021 | Knicks | 76 | Jazz | 97 |
| April | 4, 2021 | Bucks | 87 | Knicks | 78 |
| April | 7, 2021 | Knicks | 83 | Pistons | 94 |
| April | 10, 2021 | Knicks | 94 | Celtics | 81 |
| April | 13, 2021 | Hawks | 78 | Knicks | 93 |
| April | 15, 2021 | Knicks | 76 | Pistons | 127 |
| April | 18, 2021 | 76ers | 88 | Knicks | 108 |
| April | 20, 2021 | Wizards | 83 | Knicks | 91 |
| April | 22, 2021 | Nets | 119 | Knicks | 120 |
| April | 23, 2021 | Knicks | 90 | Bulls | 84 |
| April | 25, 2021 | Raptors | 104 | Knicks | 105 |
| April | 27, 2021 | Knicks | 101 | Thunder | 127 |
| April | 29, 2021 | Magic | 104 | Knicks | 100 |
| May | 1, 2021 | Heat | 96 | Knicks | 91 |