| month | day | visitor | score | home | score |
|---|
| November | 2, 2012 | Lakers | 96 | Heat | 80 |
| November | 4, 2012 | Lakers | 103 | Magic | 99 |
| November | 7, 2012 | Pelicans | 100 | Lakers | 89 |
| November | 9, 2012 | Lakers | 84 | Grizzlies | 96 |
| November | 10, 2012 | Wizards | 93 | Lakers | 96 |
| November | 12, 2012 | Bobcats | 95 | Lakers | 83 |
| November | 16, 2012 | Lakers | 74 | Warriors | 94 |
| November | 17, 2012 | Lakers | 89 | Clippers | 85 |
| November | 19, 2012 | Lakers | 107 | Kings | 131 |
| November | 20, 2012 | Lakers | 101 | Nuggets | 107 |
| November | 23, 2012 | Lakers | 91 | Bulls | 104 |
| November | 25, 2012 | Lakers | 82 | Jazz | 89 |
| November | 27, 2012 | Jazz | 96 | Lakers | 86 |
| November | 28, 2012 | Nets | 97 | Lakers | 73 |
| November | 30, 2012 | Magic | 99 | Lakers | 90 |
| December | 4, 2012 | Lakers | 71 | Grizzlies | 87 |
| December | 7, 2012 | Rockets | 90 | Lakers | 75 |
| December | 9, 2012 | Mavericks | 95 | Lakers | 97 |
| December | 10, 2012 | Suns | 94 | Lakers | 99 |
| December | 13, 2012 | Raptors | 58 | Lakers | 77 |
| December | 15, 2012 | Heat | 80 | Lakers | 82 |
| December | 17, 2012 | Lakers | 82 | Timberwolves | 89 |
| December | 19, 2012 | Pelicans | 107 | Lakers | 77 |
| December | 21, 2012 | Spurs | 98 | Lakers | 90 |
| December | 26, 2012 | Trailblazers | 74 | Lakers | 67 |
| December | 29, 2012 | Warriors | 99 | Lakers | 76 |
| December | 31, 2012 | Grizzlies | 96 | Lakers | 88 |
| January | 2, 2013 | 76ers | 94 | Lakers | 76 |
| January | 3, 2013 | Knicks | 82 | Lakers | 51 |
| January | 5, 2013 | Nuggets | 110 | Lakers | 104 |
| January | 8, 2013 | Lakers | 66 | Cavaliers | 117 |
| January | 10, 2013 | Lakers | 76 | Bucks | 95 |
| January | 12, 2013 | Celtics | 93 | Lakers | 82 |
| January | 16, 2013 | Grizzlies | 86 | Lakers | 74 |
| January | 17, 2013 | Trailblazers | 98 | Lakers | 93 |
| January | 19, 2013 | Lakers | 78 | Pistons | 112 |
| January | 21, 2013 | Jazz | 73 | Lakers | 83 |
| January | 22, 2013 | Lakers | 85 | Rockets | 94 |
| January | 24, 2013 | Thunder | 93 | Lakers | 97 |
| January | 26, 2013 | Lakers | 61 | Jazz | 86 |
| January | 28, 2013 | Lakers | 74 | Trailblazers | 107 |
| January | 30, 2013 | Lakers | 75 | Rockets | 100 |
| February | 1, 2013 | Lakers | 72 | Spurs | 97 |
| February | 2, 2013 | Mavericks | 108 | Lakers | 79 |
| February | 4, 2013 | Lakers | 81 | Suns | 109 |
| February | 11, 2013 | Spurs | 119 | Lakers | 106 |
| February | 12, 2013 | Nuggets | 83 | Lakers | 92 |
| February | 14, 2013 | Lakers | 87 | Knicks | 98 |
| February | 15, 2013 | Cavaliers | 97 | Lakers | 74 |
| February | 16, 2013 | Lakers | 78 | Nets | 116 |
| February | 19, 2013 | Lakers | 105 | Thunder | 118 |
| February | 22, 2013 | Lakers | 106 | Trailblazers | 98 |
| February | 23, 2013 | Lakers | 86 | Warriors | 111 |
| February | 24, 2013 | Lakers | 95 | Bobcats | 104 |
| February | 28, 2013 | Warriors | 104 | Lakers | 71 |
| March | 1, 2013 | Lakers | 98 | Thunder | 129 |
| March | 4, 2013 | Lakers | 84 | Hawks | 100 |
| March | 8, 2013 | Lakers | 84 | 76ers | 113 |
| March | 10, 2013 | Lakers | 125 | Pacers | 120 |
| March | 11, 2013 | Clippers | 103 | Lakers | 92 |
| March | 14, 2013 | Pacers | 107 | Lakers | 103 |
| March | 15, 2013 | Lakers | 85 | Celtics | 102 |
| March | 18, 2013 | Lakers | 75 | Pelicans | 119 |
| March | 19, 2013 | Timberwolves | 90 | Lakers | 86 |
| March | 21, 2013 | Clippers | 99 | Lakers | 82 |
| March | 22, 2013 | Hawks | 105 | Lakers | 86 |
| March | 24, 2013 | Bucks | 92 | Lakers | 61 |
| March | 28, 2013 | Lakers | 81 | Wizards | 100 |
| March | 31, 2013 | Lakers | 101 | Raptors | 92 |
| April | 2, 2013 | Lakers | 59 | Suns | 115 |
| April | 6, 2013 | Lakers | 68 | Nuggets | 99 |
| April | 7, 2013 | Lakers | 76 | Timberwolves | 109 |
| April | 9, 2013 | Lakers | 72 | Mavericks | 101 |
| April | 10, 2013 | Pistons | 87 | Lakers | 68 |
| April | 12, 2013 | Lakers | 79 | Pelicans | 103 |
| April | 15, 2013 | Timberwolves | 93 | Lakers | 67 |
| April | 16, 2013 | Kings | 108 | Lakers | 101 |
| April | 20, 2013 | Lakers | 63 | Mavericks | 91 |
| April | 21, 2013 | Lakers | 91 | Spurs | 115 |
| April | 25, 2013 | Rockets | 90 | Lakers | 106 |
| April | 28, 2013 | Kings | 99 | Lakers | 93 |
| May | 1, 2013 | Bulls | 97 | Lakers | 108 |