| month | day | visitor | score | home | score |
|---|
| November | 2, 2012 | Thunder | 108 | Spurs | 118 |
| November | 3, 2012 | Hornets | 91 | Spurs | 104 |
| November | 8, 2012 | Spurs | 104 | Wizards | 102 |
| November | 10, 2012 | Wolves | 108 | Spurs | 113 |
| November | 12, 2012 | Spurs | 109 | Pacers | 106 |
| November | 15, 2012 | Spurs | 96 | 76ers | 76 |
| November | 16, 2012 | Spurs | 97 | Celtics | 105 |
| November | 17, 2012 | Spurs | 86 | Bobcats | 108 |
| November | 18, 2012 | Spurs | 125 | Magic | 101 |
| November | 19, 2012 | Spurs | 106 | Bulls | 93 |
| November | 23, 2012 | Mavericks | 115 | Spurs | 102 |
| November | 25, 2012 | Spurs | 116 | Knicks | 121 |
| November | 28, 2012 | Hornets | 115 | Spurs | 113 |
| November | 29, 2012 | Warriors | 91 | Spurs | 85 |
| November | 30, 2012 | Magic | 111 | Spurs | 106 |
| December | 1, 2012 | Rockets | 86 | Spurs | 110 |
| December | 4, 2012 | 76ers | 93 | Spurs | 120 |
| December | 6, 2012 | Spurs | 121 | Mavericks | 125 |
| December | 7, 2012 | Spurs | 112 | Hawks | 117 |
| December | 9, 2012 | Spurs | 94 | Heat | 105 |
| December | 10, 2012 | Spurs | 78 | Warriors | 98 |
| December | 11, 2012 | Spurs | 98 | Lakers | 111 |
| December | 14, 2012 | Wizards | 95 | Spurs | 97 |
| December | 15, 2012 | Jazz | 83 | Spurs | 102 |
| December | 16, 2012 | Raptors | 85 | Spurs | 123 |
| December | 21, 2012 | Spurs | 76 | Grizzlies | 130 |
| December | 25, 2012 | Spurs | 106 | Kings | 81 |
| December | 27, 2012 | Spurs | 111 | Wolves | 107 |
| December | 28, 2012 | Kings | 92 | Spurs | 117 |
| January | 1, 2013 | Spurs | 103 | Jazz | 78 |
| January | 7, 2013 | Spurs | 109 | Clippers | 93 |
| January | 8, 2013 | Spurs | 112 | Raptors | 87 |
| January | 12, 2013 | Blazers | 104 | Spurs | 122 |
| January | 15, 2013 | Lakers | 107 | Spurs | 112 |
| January | 16, 2013 | Spurs | 106 | Kings | 112 |
| January | 18, 2013 | Spurs | 102 | Hornets | 111 |
| January | 21, 2013 | Spurs | 104 | Blazers | 97 |
| January | 24, 2013 | Suns | 110 | Spurs | 99 |
| January | 26, 2013 | Spurs | 91 | Hornets | 100 |
| January | 27, 2013 | Nuggets | 78 | Spurs | 92 |
| January | 28, 2013 | Spurs | 98 | Thunder | 110 |
| January | 29, 2013 | Celtics | 107 | Spurs | 99 |
| January | 31, 2013 | Grizzlies | 103 | Spurs | 101 |
| February | 1, 2013 | Spurs | 116 | Grizzlies | 119 |
| February | 2, 2013 | Spurs | 104 | Warriors | 101 |
| February | 4, 2013 | Spurs | 87 | Blazers | 101 |
| February | 5, 2013 | Pacers | 85 | Spurs | 106 |
| February | 13, 2013 | Spurs | 73 | Bucks | 99 |
| February | 15, 2013 | Pistons | 119 | Spurs | 83 |
| February | 16, 2013 | Bucks | 89 | Spurs | 73 |
| February | 21, 2013 | Thunder | 100 | Spurs | 98 |
| February | 22, 2013 | Spurs | 74 | Suns | 104 |
| February | 23, 2013 | Warriors | 98 | Spurs | 83 |
| February | 26, 2013 | Jazz | 86 | Spurs | 106 |
| February | 28, 2013 | Nets | 93 | Spurs | 94 |
| March | 2, 2013 | Grizzlies | 117 | Spurs | 92 |
| March | 3, 2013 | Heat | 111 | Spurs | 93 |
| March | 5, 2013 | Spurs | 92 | Pistons | 122 |
| March | 7, 2013 | Spurs | 111 | Cavaliers | 108 |
| March | 8, 2013 | Suns | 93 | Spurs | 97 |
| March | 10, 2013 | Clippers | 81 | Spurs | 102 |
| March | 11, 2013 | Rockets | 97 | Spurs | 98 |
| March | 12, 2013 | Mavericks | 120 | Spurs | 122 |
| March | 15, 2013 | Cavaliers | 123 | Spurs | 118 |
| March | 16, 2013 | Spurs | 83 | Nuggets | 100 |
| March | 19, 2013 | Bulls | 116 | Spurs | 117 |
| March | 21, 2013 | Spurs | 97 | Mavericks | 123 |
| March | 23, 2013 | Spurs | 94 | Nets | 89 |
| March | 27, 2013 | Spurs | 115 | Suns | 107 |
| March | 28, 2013 | Spurs | 104 | Thunder | 115 |
| April | 1, 2013 | Bobcats | 113 | Spurs | 112 |
| April | 2, 2013 | Clippers | 97 | Spurs | 120 |
| April | 3, 2013 | Hawks | 114 | Spurs | 96 |
| April | 5, 2013 | Spurs | 105 | Clippers | 127 |
| April | 7, 2013 | Spurs | 90 | Rockets | 113 |
| April | 9, 2013 | Spurs | 85 | Lakers | 108 |
| April | 16, 2013 | Kings | 97 | Spurs | 120 |
| April | 20, 2013 | Nuggets | 111 | Spurs | 113 |
| April | 21, 2013 | Knicks | 87 | Spurs | 77 |
| April | 23, 2013 | Lakers | 87 | Spurs | 122 |
| April | 26, 2013 | Spurs | 119 | Jazz | 92 |
| April | 27, 2013 | Spurs | 90 | Wolves | 97 |
| Post | 1, 2013 | Spurs | 74 | Hornets | 101 |
| Post | 2, 2013 | Spurs | 114 | Hornets | 108 |
| Post | 3, 2013 | Hornets | 100 | Spurs | 103 |
| Post | 4, 2013 | Hornets | 102 | Spurs | 107 |
| Post | 5, 2013 | Spurs | 98 | Hornets | 107 |
| Post | 6, 2013 | Hornets | 106 | Spurs | 103 |
| Post | 7, 2013 | Spurs | 98 | Hornets | 113 |