| month | day | visitor | score | home | score |
|---|
| November | 2, 2024 | Magic | 110 | Trailblazers | 115 |
| November | 4, 2024 | Pacers | 81 | Trailblazers | 119 |
| November | 6, 2024 | Trailblazers | 136 | Nets | 140 |
| November | 7, 2024 | Suns | 120 | Trailblazers | 110 |
| November | 10, 2024 | Nuggets | 111 | Trailblazers | 88 |
| November | 12, 2024 | Thunder | 95 | Trailblazers | 112 |
| November | 13, 2024 | Wizards | 99 | Trailblazers | 92 |
| November | 15, 2024 | Trailblazers | 92 | Hawks | 87 |
| November | 18, 2024 | Bucks | 99 | Trailblazers | 118 |
| November | 21, 2024 | Trailblazers | 111 | Spurs | 134 |
| November | 22, 2024 | Jazz | 106 | Trailblazers | 108 |
| November | 26, 2024 | Warriors | 107 | Trailblazers | 133 |
| November | 29, 2024 | Trailblazers | 99 | Thunder | 102 |
| December | 1, 2024 | Grizzlies | 97 | Trailblazers | 102 |
| December | 5, 2024 | Clippers | 143 | Trailblazers | 130 |
| December | 7, 2024 | Cavaliers | 85 | Trailblazers | 105 |
| December | 8, 2024 | Knicks | 102 | Trailblazers | 111 |
| December | 11, 2024 | Trailblazers | 108 | Jazz | 124 |
| December | 14, 2024 | Trailblazers | 106 | Pacers | 114 |
| December | 15, 2024 | Kings | 89 | Trailblazers | 116 |
| December | 16, 2024 | Rockets | 119 | Trailblazers | 105 |
| December | 18, 2024 | Trailblazers | 106 | Cavaliers | 73 |
| December | 19, 2024 | Pistons | 129 | Trailblazers | 155 |
| December | 22, 2024 | Trailblazers | 102 | Jazz | 117 |
| December | 23, 2024 | Spurs | 130 | Trailblazers | 123 |
| December | 26, 2024 | Trailblazers | 92 | Lakers | 104 |
| December | 28, 2024 | Trailblazers | 110 | Mavericks | 120 |
| December | 29, 2024 | Mavericks | 95 | Trailblazers | 102 |
| December | 31, 2024 | Hornets | 100 | Trailblazers | 121 |
| January | 3, 2025 | Trailblazers | 109 | Heat | 90 |
| January | 5, 2025 | Trailblazers | 91 | Wizards | 110 |
| January | 8, 2025 | Trailblazers | 115 | Celtics | 107 |
| January | 9, 2025 | Trailblazers | 93 | Bulls | 111 |
| January | 12, 2025 | Raptors | 113 | Trailblazers | 107 |
| January | 13, 2025 | Trailblazers | 89 | Nuggets | 92 |
| January | 15, 2025 | Trailblazers | 97 | Grizzlies | 99 |
| January | 17, 2025 | Trailblazers | 116 | Lakers | 89 |
| January | 20, 2025 | 76ers | 94 | Trailblazers | 98 |
| January | 21, 2025 | Warriors | 122 | Trailblazers | 101 |
| January | 23, 2025 | Suns | 101 | Trailblazers | 133 |
| January | 24, 2025 | Trailblazers | 95 | Warriors | 105 |
| January | 28, 2025 | Lakers | 108 | Trailblazers | 115 |
| January | 29, 2025 | Mavericks | 111 | Trailblazers | 119 |
| February | 1, 2025 | Trailblazers | 111 | Warriors | 112 |
| February | 2, 2025 | Trailblazers | 105 | Clippers | 116 |
| February | 6, 2025 | Pelicans | 84 | Trailblazers | 102 |
| February | 13, 2025 | Trailblazers | 129 | Rockets | 122 |
| February | 14, 2025 | Trailblazers | 128 | Pistons | 118 |
| February | 18, 2025 | Rockets | 95 | Trailblazers | 111 |
| February | 21, 2025 | Trailblazers | 89 | Rockets | 109 |
| February | 22, 2025 | Lakers | 94 | Trailblazers | 124 |
| February | 24, 2025 | Trailblazers | 97 | Suns | 106 |
| February | 25, 2025 | Nuggets | 112 | Trailblazers | 98 |
| February | 27, 2025 | Trailblazers | 97 | Wolves | 95 |
| March | 1, 2025 | Heat | 92 | Trailblazers | 99 |
| March | 2, 2025 | Bulls | 90 | Trailblazers | 108 |
| March | 6, 2025 | Wolves | 94 | Trailblazers | 101 |
| March | 9, 2025 | Trailblazers | 86 | Pelicans | 90 |
| March | 10, 2025 | Thunder | 103 | Trailblazers | 93 |
| March | 12, 2025 | Trailblazers | 107 | Mavericks | 108 |
| March | 15, 2025 | Trailblazers | 94 | Grizzlies | 122 |
| March | 18, 2025 | Trailblazers | 105 | 76ers | 98 |
| March | 19, 2025 | Grizzlies | 94 | Trailblazers | 106 |
| March | 23, 2025 | Trailblazers | 89 | Thunder | 94 |
| March | 25, 2025 | Trailblazers | 92 | Bucks | 99 |
| March | 28, 2025 | Trailblazers | 87 | Nuggets | 100 |
| March | 30, 2025 | Pelicans | 98 | Trailblazers | 95 |
| March | 31, 2025 | Nets | 104 | Trailblazers | 96 |
| April | 2, 2025 | Trailblazers | 88 | Hornets | 96 |
| April | 5, 2025 | Trailblazers | 87 | Kings | 93 |
| April | 9, 2025 | Hawks | 84 | Trailblazers | 86 |
| April | 11, 2025 | Wolves | 95 | Trailblazers | 91 |
| April | 12, 2025 | Celtics | 103 | Trailblazers | 94 |
| April | 15, 2025 | Jazz | 89 | Trailblazers | 106 |
| April | 17, 2025 | Trailblazers | 95 | Knicks | 105 |
| April | 18, 2025 | Trailblazers | 96 | Pelicans | 106 |
| April | 21, 2025 | Trailblazers | 79 | Raptors | 112 |
| April | 22, 2025 | Trailblazers | 78 | Magic | 110 |
| April | 24, 2025 | Trailblazers | 96 | Kings | 112 |
| April | 27, 2025 | Trailblazers | 102 | Suns | 134 |
| April | 29, 2025 | Trailblazers | 78 | Clippers | 94 |
| April | 30, 2025 | Spurs | 138 | Trailblazers | 110 |