| month | day | visitor | score | home | score |
|---|
| November | 3, 2022 | Rockets | 95 | Grizzlies | 112 |
| November | 5, 2022 | Grizzlies | 93 | Cavaliers | 79 |
| November | 6, 2022 | Grizzlies | 71 | Clippers | 102 |
| November | 7, 2022 | Grizzlies | 111 | 76ers | 99 |
| November | 9, 2022 | Lakers | 104 | Grizzlies | 117 |
| November | 10, 2022 | Grizzlies | 99 | Pacers | 114 |
| November | 12, 2022 | Spurs | 122 | Grizzlies | 99 |
| November | 14, 2022 | Grizzlies | 120 | Celtics | 115 |
| November | 15, 2022 | Grizzlies | 107 | Hornets | 98 |
| November | 18, 2022 | Knicks | 98 | Grizzlies | 116 |
| November | 19, 2022 | Grizzlies | 102 | Spurs | 116 |
| November | 21, 2022 | Hornets | 95 | Grizzlies | 99 |
| November | 22, 2022 | Celtics | 103 | Grizzlies | 108 |
| November | 26, 2022 | Grizzlies | 97 | Kings | 116 |
| November | 29, 2022 | Suns | 102 | Grizzlies | 78 |
| November | 30, 2022 | Grizzlies | 85 | Rockets | 107 |
| December | 1, 2022 | Grizzlies | 104 | Trailblazers | 108 |
| December | 3, 2022 | Grizzlies | 114 | Thunder | 133 |
| December | 4, 2022 | Lakers | 92 | Grizzlies | 106 |
| December | 6, 2022 | Pelicans | 114 | Grizzlies | 121 |
| December | 8, 2022 | Grizzlies | 92 | Wizards | 85 |
| December | 12, 2022 | Grizzlies | 101 | Wolves | 106 |
| December | 13, 2022 | Rockets | 104 | Grizzlies | 113 |
| December | 15, 2022 | Pelicans | 115 | Grizzlies | 112 |
| December | 17, 2022 | Thunder | 124 | Grizzlies | 111 |
| December | 18, 2022 | Grizzlies | 84 | Nuggets | 99 |
| December | 20, 2022 | Kings | 130 | Grizzlies | 120 |
| December | 26, 2022 | Grizzlies | 111 | Thunder | 141 |
| December | 27, 2022 | Grizzlies | 105 | Hawks | 113 |
| December | 31, 2022 | Grizzlies | 110 | Lakers | 92 |
| January | 2, 2023 | Grizzlies | 106 | Spurs | 118 |
| January | 4, 2023 | Grizzlies | 94 | Rockets | 109 |
| January | 6, 2023 | Bulls | 111 | Grizzlies | 88 |
| January | 10, 2023 | Grizzlies | 104 | Suns | 110 |
| January | 11, 2023 | Grizzlies | 94 | Pistons | 90 |
| January | 15, 2023 | Trailblazers | 99 | Grizzlies | 95 |
| January | 16, 2023 | Grizzlies | 76 | Lakers | 100 |
| January | 18, 2023 | Kings | 92 | Grizzlies | 104 |
| January | 20, 2023 | Grizzlies | 87 | Jazz | 102 |
| January | 21, 2023 | Heat | 89 | Grizzlies | 91 |
| January | 24, 2023 | Grizzlies | 104 | Magic | 107 |
| January | 26, 2023 | Raptors | 95 | Grizzlies | 62 |
| January | 30, 2023 | Grizzlies | 103 | Suns | 90 |
| February | 1, 2023 | Grizzlies | 91 | Knicks | 115 |
| February | 2, 2023 | Jazz | 111 | Grizzlies | 108 |
| February | 4, 2023 | Magic | 108 | Grizzlies | 103 |
| February | 13, 2023 | Pacers | 132 | Grizzlies | 124 |
| February | 15, 2023 | Warriors | 109 | Grizzlies | 123 |
| February | 17, 2023 | Nuggets | 99 | Grizzlies | 85 |
| February | 19, 2023 | Nuggets | 88 | Grizzlies | 81 |
| February | 21, 2023 | Grizzlies | 87 | Mavericks | 97 |
| February | 24, 2023 | Grizzlies | 88 | Bulls | 108 |
| February | 25, 2023 | Grizzlies | 98 | Heat | 96 |
| March | 1, 2023 | Warriors | 96 | Grizzlies | 79 |
| March | 3, 2023 | Grizzlies | 80 | Bucks | 108 |
| March | 4, 2023 | Clippers | 104 | Grizzlies | 92 |
| March | 7, 2023 | Grizzlies | 90 | Clippers | 112 |
| March | 10, 2023 | 76ers | 125 | Grizzlies | 117 |
| March | 13, 2023 | Grizzlies | 127 | Pelicans | 115 |
| March | 15, 2023 | Trailblazers | 90 | Grizzlies | 101 |
| March | 19, 2023 | Grizzlies | 91 | Trailblazers | 79 |
| March | 23, 2023 | Wolves | 88 | Grizzlies | 81 |
| March | 25, 2023 | Grizzlies | 103 | Raptors | 102 |
| March | 26, 2023 | Grizzlies | 90 | Wolves | 99 |
| March | 28, 2023 | Spurs | 133 | Grizzlies | 117 |
| March | 29, 2023 | Hawks | 97 | Grizzlies | 100 |
| March | 31, 2023 | Grizzlies | 86 | Nuggets | 104 |
| April | 2, 2023 | Bucks | 91 | Grizzlies | 103 |
| April | 4, 2023 | Thunder | 123 | Grizzlies | 111 |
| April | 8, 2023 | Grizzlies | 104 | Mavericks | 116 |
| April | 11, 2023 | Grizzlies | 90 | Nets | 93 |
| April | 13, 2023 | Suns | 89 | Grizzlies | 81 |
| April | 14, 2023 | Pistons | 99 | Grizzlies | 109 |
| April | 18, 2023 | Clippers | 104 | Grizzlies | 97 |
| April | 19, 2023 | Nets | 91 | Grizzlies | 98 |
| April | 21, 2023 | Grizzlies | 92 | Kings | 111 |
| April | 22, 2023 | Wolves | 83 | Grizzlies | 102 |
| April | 24, 2023 | Grizzlies | 99 | Jazz | 90 |
| April | 25, 2023 | Mavericks | 103 | Grizzlies | 115 |
| April | 27, 2023 | Cavaliers | 89 | Grizzlies | 111 |
| April | 30, 2023 | Grizzlies | 100 | Warriors | 122 |
| May | 1, 2023 | Wizards | 114 | Grizzlies | 102 |