| month | day | visitor | score | home | score |
|---|
| November | 4, 2021 | Nuggets | 115 | Clippers | 84 |
| November | 7, 2021 | Suns | 105 | Nuggets | 121 |
| November | 8, 2021 | Warriors | 105 | Nuggets | 133 |
| November | 10, 2021 | Kings | 115 | Nuggets | 128 |
| November | 13, 2021 | Nuggets | 113 | Lakers | 114 |
| November | 18, 2021 | Pelicans | 104 | Nuggets | 91 |
| November | 20, 2021 | Nuggets | 90 | Bulls | 112 |
| November | 21, 2021 | Nuggets | 116 | Cavaliers | 109 |
| November | 23, 2021 | Jazz | 112 | Nuggets | 109 |
| November | 25, 2021 | Celtics | 85 | Nuggets | 102 |
| November | 27, 2021 | Nuggets | 96 | Grizzlies | 89 |
| November | 29, 2021 | Nets | 95 | Nuggets | 98 |
| December | 1, 2021 | Bucks | 114 | Nuggets | 100 |
| December | 3, 2021 | Rockets | 87 | Nuggets | 102 |
| December | 5, 2021 | Hawks | 82 | Nuggets | 91 |
| December | 7, 2021 | Nuggets | 79 | Pelicans | 98 |
| December | 9, 2021 | Nuggets | 111 | Bucks | 112 |
| December | 11, 2021 | Nuggets | 82 | Wolves | 102 |
| December | 14, 2021 | Magic | 119 | Nuggets | 118 |
| December | 15, 2021 | Nuggets | 118 | Thunder | 110 |
| December | 18, 2021 | Lakers | 86 | Nuggets | 119 |
| December | 21, 2021 | Nuggets | 102 | Trailblazers | 113 |
| December | 25, 2021 | Nuggets | 96 | Raptors | 112 |
| December | 27, 2021 | Nuggets | 122 | Magic | 119 |
| December | 29, 2021 | Nuggets | 102 | Hornets | 105 |
| December | 30, 2021 | Nuggets | 92 | Hawks | 94 |
| January | 1, 2022 | Grizzlies | 82 | Nuggets | 78 |
| January | 5, 2022 | Thunder | 101 | Nuggets | 114 |
| January | 7, 2022 | Raptors | 111 | Nuggets | 116 |
| January | 9, 2022 | Mavericks | 107 | Nuggets | 118 |
| January | 13, 2022 | Nuggets | 96 | Clippers | 106 |
| January | 16, 2022 | Nuggets | 118 | Spurs | 125 |
| January | 18, 2022 | Spurs | 110 | Nuggets | 103 |
| January | 19, 2022 | Nuggets | 103 | Suns | 94 |
| January | 22, 2022 | Knicks | 94 | Nuggets | 82 |
| January | 24, 2022 | Nuggets | 126 | Kings | 98 |
| January | 26, 2022 | Hornets | 99 | Nuggets | 89 |
| January | 28, 2022 | Nuggets | 95 | Rockets | 84 |
| January | 29, 2022 | Nuggets | 93 | Heat | 99 |
| January | 31, 2022 | Clippers | 119 | Nuggets | 135 |
| February | 2, 2022 | Nuggets | 103 | Suns | 116 |
| February | 4, 2022 | Trailblazers | 105 | Nuggets | 96 |
| February | 6, 2022 | Warriors | 114 | Nuggets | 101 |
| February | 13, 2022 | Bulls | 112 | Nuggets | 101 |
| February | 15, 2022 | Cavaliers | 114 | Nuggets | 104 |
| February | 19, 2022 | Nuggets | 96 | Jazz | 107 |
| February | 21, 2022 | Suns | 104 | Nuggets | 123 |
| February | 22, 2022 | 76ers | 78 | Nuggets | 105 |
| February | 24, 2022 | Nuggets | 92 | Grizzlies | 129 |
| February | 26, 2022 | Nuggets | 96 | Pelicans | 119 |
| February | 28, 2022 | Rockets | 103 | Nuggets | 86 |
| March | 2, 2022 | Nuggets | 90 | Wolves | 102 |
| March | 4, 2022 | Nuggets | 92 | Pistons | 90 |
| March | 6, 2022 | Nuggets | 66 | Nets | 89 |
| March | 8, 2022 | Nuggets | 106 | 76ers | 86 |
| March | 11, 2022 | Heat | 92 | Nuggets | 99 |
| March | 13, 2022 | Kings | 107 | Nuggets | 127 |
| March | 16, 2022 | Nuggets | 96 | Mavericks | 93 |
| March | 18, 2022 | Clippers | 92 | Nuggets | 110 |
| March | 20, 2022 | Thunder | 87 | Nuggets | 117 |
| March | 22, 2022 | Jazz | 112 | Nuggets | 108 |
| March | 24, 2022 | Pelicans | 97 | Nuggets | 102 |
| March | 26, 2022 | Nuggets | 117 | Spurs | 112 |
| March | 28, 2022 | Nuggets | 122 | Lakers | 118 |
| March | 30, 2022 | Nuggets | 74 | Warriors | 87 |
| April | 3, 2022 | Wolves | 95 | Nuggets | 97 |
| April | 5, 2022 | Mavericks | 65 | Nuggets | 108 |
| April | 7, 2022 | Pacers | 125 | Nuggets | 127 |
| April | 9, 2022 | Nuggets | 108 | Celtics | 91 |
| April | 12, 2022 | Nuggets | 104 | Wizards | 105 |
| April | 13, 2022 | Nuggets | 96 | Knicks | 83 |
| April | 15, 2022 | Nuggets | 108 | Pacers | 124 |
| April | 17, 2022 | Pistons | 112 | Nuggets | 105 |
| April | 19, 2022 | Nuggets | 87 | Rockets | 92 |
| April | 20, 2022 | Nuggets | 97 | Thunder | 122 |
| April | 22, 2022 | Wizards | 101 | Nuggets | 81 |
| April | 24, 2022 | Nuggets | 92 | Warriors | 95 |
| April | 25, 2022 | Spurs | 117 | Nuggets | 120 |
| April | 27, 2022 | Trailblazers | 85 | Nuggets | 92 |
| April | 29, 2022 | Nuggets | 73 | Trailblazers | 101 |
| April | 30, 2022 | Nuggets | 114 | Jazz | 91 |
| May | 1, 2022 | Wolves | 91 | Nuggets | 86 |
| Post | 1, 2022 | Nuggets | 116 | Clippers | 120 |
| Post | 2, 2022 | Nuggets | 100 | Clippers | 127 |
| Post | 3, 2022 | Clippers | 91 | Nuggets | 104 |
| Post | 4, 2022 | Clippers | 102 | Nuggets | 111 |
| Post | 5, 2022 | Nuggets | 111 | Clippers | 83 |
| Post | 6, 2022 | Clippers | 100 | Nuggets | 98 |
| Post | 7, 2022 | Nuggets | 97 | Clippers | 122 |