| month | day | visitor | score | home | score |
|---|
| November | 3, 2021 | Nuggets | 99 | Clippers | 116 |
| November | 4, 2021 | Grizzlies | 127 | Nuggets | 109 |
| November | 6, 2021 | Suns | 118 | Nuggets | 99 |
| November | 9, 2021 | Nuggets | 106 | Thunder | 120 |
| November | 11, 2021 | Rockets | 85 | Nuggets | 81 |
| November | 14, 2021 | Pacers | 137 | Nuggets | 111 |
| November | 15, 2021 | Mavericks | 116 | Nuggets | 107 |
| November | 17, 2021 | Nuggets | 130 | Lakers | 137 |
| November | 19, 2021 | Trailblazers | 89 | Nuggets | 91 |
| November | 21, 2021 | Nuggets | 93 | Jazz | 124 |
| November | 22, 2021 | Pelicans | 109 | Nuggets | 104 |
| November | 24, 2021 | Nuggets | 88 | 76ers | 95 |
| November | 25, 2021 | Nuggets | 98 | Celtics | 114 |
| November | 27, 2021 | Nuggets | 91 | Raptors | 124 |
| November | 29, 2021 | Kings | 107 | Nuggets | 128 |
| December | 1, 2021 | Nuggets | 102 | Spurs | 127 |
| December | 3, 2021 | Raptors | 127 | Nuggets | 87 |
| December | 6, 2021 | Nets | 106 | Nuggets | 92 |
| December | 9, 2021 | Hornets | 118 | Nuggets | 96 |
| December | 12, 2021 | Nuggets | 93 | Warriors | 130 |
| December | 14, 2021 | Nuggets | 76 | Rockets | 105 |
| December | 16, 2021 | Kings | 103 | Nuggets | 109 |
| December | 18, 2021 | Nuggets | 108 | Heat | 117 |
| December | 21, 2021 | Nuggets | 100 | Bucks | 127 |
| December | 26, 2021 | Clippers | 118 | Nuggets | 107 |
| December | 28, 2021 | Wizards | 97 | Nuggets | 103 |
| December | 30, 2021 | Nuggets | 100 | Pelicans | 110 |
| January | 2, 2022 | Nuggets | 104 | Clippers | 132 |
| January | 3, 2022 | Wolves | 116 | Nuggets | 110 |
| January | 6, 2022 | Warriors | 120 | Nuggets | 118 |
| January | 8, 2022 | 76ers | 88 | Nuggets | 80 |
| January | 10, 2022 | Trailblazers | 89 | Nuggets | 81 |
| January | 13, 2022 | Nuggets | 87 | Rockets | 109 |
| January | 14, 2022 | Nuggets | 90 | Mavericks | 116 |
| January | 16, 2022 | Magic | 128 | Nuggets | 111 |
| January | 18, 2022 | Hawks | 136 | Nuggets | 91 |
| January | 20, 2022 | Nuggets | 119 | Suns | 133 |
| January | 21, 2022 | Celtics | 143 | Nuggets | 135 |
| January | 23, 2022 | Nuggets | 79 | Bulls | 111 |
| January | 25, 2022 | Nuggets | 104 | Cavaliers | 135 |
| January | 27, 2022 | Nuggets | 83 | Wizards | 102 |
| January | 30, 2022 | Nuggets | 74 | Hornets | 98 |
| February | 1, 2022 | Lakers | 106 | Nuggets | 115 |
| February | 4, 2022 | Knicks | 87 | Nuggets | 112 |
| February | 6, 2022 | Nuggets | 97 | Grizzlies | 124 |
| February | 14, 2022 | Thunder | 131 | Nuggets | 120 |
| February | 15, 2022 | Pistons | 74 | Nuggets | 82 |
| February | 18, 2022 | Nuggets | 97 | Grizzlies | 106 |
| February | 19, 2022 | Warriors | 121 | Nuggets | 125 |
| February | 21, 2022 | Nuggets | 103 | Suns | 125 |
| February | 24, 2022 | Bucks | 126 | Nuggets | 112 |
| February | 25, 2022 | Nuggets | 92 | Trailblazers | 102 |
| February | 28, 2022 | Mavericks | 88 | Nuggets | 78 |
| March | 2, 2022 | Cavaliers | 117 | Nuggets | 108 |
| March | 4, 2022 | Nuggets | 93 | Hawks | 117 |
| March | 6, 2022 | Nuggets | 111 | Nets | 97 |
| March | 9, 2022 | Nuggets | 86 | Knicks | 89 |
| March | 11, 2022 | Spurs | 108 | Nuggets | 93 |
| March | 14, 2022 | Bulls | 116 | Nuggets | 106 |
| March | 15, 2022 | Nuggets | 83 | Pelicans | 104 |
| March | 18, 2022 | Rockets | 105 | Nuggets | 73 |
| March | 20, 2022 | Nuggets | 102 | Kings | 125 |
| March | 21, 2022 | Jazz | 127 | Nuggets | 123 |
| March | 23, 2022 | Nuggets | 92 | Pacers | 109 |
| March | 25, 2022 | Nuggets | 109 | Magic | 119 |
| March | 28, 2022 | Lakers | 120 | Nuggets | 103 |
| March | 31, 2022 | Thunder | 114 | Nuggets | 120 |
| April | 2, 2022 | Nuggets | 87 | Trailblazers | 98 |
| April | 5, 2022 | Nuggets | 101 | Kings | 123 |
| April | 7, 2022 | Heat | 117 | Nuggets | 86 |
| April | 10, 2022 | Nuggets | 100 | Spurs | 140 |
| April | 11, 2022 | Pelicans | 98 | Nuggets | 106 |
| April | 13, 2022 | Nuggets | 101 | Thunder | 100 |
| April | 15, 2022 | Nuggets | 90 | Mavericks | 115 |
| April | 17, 2022 | Jazz | 133 | Nuggets | 115 |
| April | 19, 2022 | Nuggets | 106 | Wolves | 120 |
| April | 22, 2022 | Clippers | 124 | Nuggets | 98 |
| April | 24, 2022 | Nuggets | 73 | Pistons | 118 |
| April | 25, 2022 | Grizzlies | 115 | Nuggets | 96 |
| April | 27, 2022 | Nuggets | 126 | Lakers | 119 |
| April | 29, 2022 | Wolves | 121 | Nuggets | 104 |
| May | 1, 2022 | Nuggets | 96 | Warriors | 147 |