| month | day | visitor | score | home | score |
|---|
| November | 4, 2020 | Wolves | 104 | Spurs | 131 |
| November | 6, 2020 | Cavaliers | 116 | Wolves | 122 |
| November | 7, 2020 | Wolves | 115 | Mavericks | 104 |
| November | 9, 2020 | Pacers | 88 | Wolves | 116 |
| November | 11, 2020 | Wolves | 122 | Raptors | 118 |
| November | 14, 2020 | Bucks | 114 | Wolves | 93 |
| November | 18, 2020 | Lakers | 110 | Wolves | 106 |
| November | 20, 2020 | Jazz | 92 | Wolves | 101 |
| November | 22, 2020 | Wolves | 118 | Warriors | 102 |
| November | 24, 2020 | Wolves | 101 | Trailblazers | 98 |
| November | 25, 2020 | Wolves | 113 | Clippers | 93 |
| November | 27, 2020 | Wolves | 96 | Lakers | 100 |
| November | 29, 2020 | Wolves | 66 | Kings | 97 |
| December | 2, 2020 | Nets | 91 | Wolves | 117 |
| December | 4, 2020 | Pelicans | 98 | Wolves | 92 |
| December | 6, 2020 | Trailblazers | 99 | Wolves | 137 |
| December | 8, 2020 | Grizzlies | 98 | Wolves | 111 |
| December | 11, 2020 | Nuggets | 77 | Wolves | 114 |
| December | 13, 2020 | Wolves | 109 | Nets | 85 |
| December | 15, 2020 | Bulls | 75 | Wolves | 97 |
| December | 17, 2020 | Wolves | 111 | Cavaliers | 99 |
| December | 19, 2020 | Spurs | 93 | Wolves | 110 |
| December | 22, 2020 | Celtics | 98 | Wolves | 125 |
| December | 25, 2020 | Rockets | 86 | Wolves | 84 |
| December | 27, 2020 | Hornets | 82 | Wolves | 93 |
| December | 30, 2020 | Wolves | 116 | Trailblazers | 114 |
| January | 1, 2021 | Wolves | 102 | Warriors | 105 |
| January | 3, 2021 | Wolves | 67 | Kings | 88 |
| January | 6, 2021 | Wolves | 97 | Suns | 110 |
| January | 8, 2021 | Kings | 96 | Wolves | 89 |
| January | 11, 2021 | Pistons | 113 | Wolves | 90 |
| January | 12, 2021 | Wolves | 116 | Spurs | 111 |
| January | 14, 2021 | Wolves | 119 | Thunder | 85 |
| January | 16, 2021 | Wolves | 98 | Bulls | 102 |
| January | 18, 2021 | Hawks | 108 | Wolves | 124 |
| January | 20, 2021 | Wolves | 102 | Heat | 92 |
| January | 21, 2021 | Wolves | 106 | Pelicans | 92 |
| January | 23, 2021 | Wolves | 123 | Celtics | 101 |
| January | 25, 2021 | Magic | 103 | Wolves | 104 |
| January | 27, 2021 | Lakers | 107 | Wolves | 102 |
| January | 29, 2021 | Wolves | 102 | Thunder | 103 |
| February | 1, 2021 | Mavericks | 110 | Wolves | 95 |
| February | 2, 2021 | Pelicans | 88 | Wolves | 96 |
| February | 6, 2021 | Wolves | 99 | 76ers | 111 |
| February | 14, 2021 | Spurs | 110 | Wolves | 127 |
| February | 16, 2021 | Suns | 111 | Wolves | 123 |
| February | 18, 2021 | Wolves | 111 | Suns | 119 |
| February | 20, 2021 | Wolves | 111 | Lakers | 98 |
| February | 21, 2021 | Wolves | 85 | Jazz | 81 |
| February | 23, 2021 | Jazz | 72 | Wolves | 86 |
| February | 26, 2021 | Grizzlies | 104 | Wolves | 134 |
| March | 2, 2021 | Nuggets | 82 | Wolves | 121 |
| March | 5, 2021 | Wolves | 118 | Grizzlies | 105 |
| March | 7, 2021 | Wolves | 128 | Magic | 106 |
| March | 8, 2021 | Wolves | 89 | Pelicans | 94 |
| March | 11, 2021 | Clippers | 95 | Wolves | 123 |
| March | 13, 2021 | Rockets | 88 | Wolves | 75 |
| March | 16, 2021 | Wolves | 88 | Knicks | 97 |
| March | 17, 2021 | Wolves | 110 | Bucks | 113 |
| March | 19, 2021 | Kings | 107 | Wolves | 79 |
| March | 21, 2021 | Wolves | 106 | Hawks | 97 |
| March | 22, 2021 | Wolves | 127 | Pacers | 109 |
| March | 25, 2021 | Wolves | 98 | Wizards | 96 |
| March | 27, 2021 | Thunder | 102 | Wolves | 123 |
| March | 28, 2021 | Wolves | 87 | Pistons | 97 |
| March | 31, 2021 | Wizards | 89 | Wolves | 87 |
| April | 1, 2021 | Knicks | 79 | Wolves | 84 |
| April | 3, 2021 | Wolves | 112 | Nuggets | 98 |
| April | 5, 2021 | Wolves | 74 | Jazz | 89 |
| April | 8, 2021 | Wolves | 95 | Rockets | 97 |
| April | 10, 2021 | Warriors | 92 | Wolves | 118 |
| April | 12, 2021 | Wolves | 95 | Hornets | 90 |
| April | 14, 2021 | Wolves | 99 | Grizzlies | 103 |
| April | 17, 2021 | Clippers | 79 | Wolves | 115 |
| April | 20, 2021 | Warriors | 93 | Wolves | 111 |
| April | 21, 2021 | 76ers | 96 | Wolves | 121 |
| April | 23, 2021 | Trailblazers | 101 | Wolves | 121 |
| April | 25, 2021 | Wolves | 103 | Mavericks | 114 |
| April | 27, 2021 | Heat | 63 | Wolves | 108 |
| April | 29, 2021 | Thunder | 93 | Wolves | 113 |
| April | 30, 2021 | Raptors | 110 | Wolves | 98 |
| May | 1, 2021 | Wolves | 113 | Nuggets | 114 |
| Post | 1, 2021 | Wolves | 111 | Mavericks | 123 |
| Post | 2, 2021 | Wolves | 105 | Mavericks | 104 |
| Post | 3, 2021 | Mavericks | 104 | Wolves | 118 |
| Post | 4, 2021 | Mavericks | 89 | Wolves | 100 |
| Post | 5, 2021 | Wolves | 99 | Mavericks | 121 |
| Post | 6, 2021 | Mavericks | 113 | Wolves | 100 |
| Post | 7, 2021 | Wolves | 105 | Mavericks | 112 |