| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Cavaliers | 94 | Raptors | 106 |
| November | 6, 2020 | Celtics | 118 | Raptors | 127 |
| November | 7, 2020 | Raptors | 89 | Wizards | 95 |
| November | 9, 2020 | Hornets | 81 | Raptors | 93 |
| November | 11, 2020 | Wolves | 122 | Raptors | 118 |
| November | 14, 2020 | Mavericks | 109 | Raptors | 115 |
| November | 18, 2020 | Raptors | 109 | Bucks | 97 |
| November | 19, 2020 | 76ers | 111 | Raptors | 120 |
| November | 22, 2020 | Raptors | 133 | Suns | 102 |
| November | 24, 2020 | Raptors | 116 | Lakers | 108 |
| November | 25, 2020 | Raptors | 87 | Jazz | 90 |
| November | 27, 2020 | Raptors | 97 | Kings | 91 |
| November | 30, 2020 | Knicks | 89 | Raptors | 112 |
| December | 2, 2020 | Pelicans | 96 | Raptors | 115 |
| December | 4, 2020 | Pistons | 90 | Raptors | 113 |
| December | 6, 2020 | Raptors | 135 | Celtics | 93 |
| December | 7, 2020 | Raptors | 111 | Bulls | 108 |
| December | 10, 2020 | Raptors | 122 | Magic | 129 |
| December | 12, 2020 | Raptors | 122 | Hawks | 101 |
| December | 13, 2020 | Wizards | 93 | Raptors | 112 |
| December | 16, 2020 | Heat | 74 | Raptors | 131 |
| December | 18, 2020 | Raptors | 127 | Grizzlies | 119 |
| December | 20, 2020 | Warriors | 92 | Raptors | 120 |
| December | 22, 2020 | Raptors | 131 | Cavaliers | 111 |
| December | 25, 2020 | Nuggets | 87 | Raptors | 117 |
| December | 27, 2020 | 76ers | 106 | Raptors | 121 |
| December | 29, 2020 | Raptors | 113 | Nets | 88 |
| December | 31, 2020 | Bucks | 105 | Raptors | 89 |
| January | 2, 2021 | Raptors | 99 | Clippers | 96 |
| January | 3, 2021 | Raptors | 94 | Warriors | 100 |
| January | 5, 2021 | Raptors | 88 | Trailblazers | 103 |
| January | 7, 2021 | Raptors | 95 | Nuggets | 85 |
| January | 10, 2021 | Pacers | 112 | Raptors | 96 |
| January | 12, 2021 | Cavaliers | 102 | Raptors | 116 |
| January | 13, 2021 | Raptors | 120 | 76ers | 139 |
| January | 16, 2021 | Raptors | 96 | Heat | 86 |
| January | 18, 2021 | Raptors | 117 | Magic | 122 |
| January | 20, 2021 | Bulls | 97 | Raptors | 122 |
| January | 22, 2021 | Jazz | 104 | Raptors | 117 |
| January | 24, 2021 | Raptors | 118 | Spurs | 110 |
| January | 26, 2021 | Raptors | 107 | Bucks | 101 |
| January | 27, 2021 | Pacers | 109 | Raptors | 143 |
| January | 29, 2021 | Hawks | 103 | Raptors | 129 |
| February | 1, 2021 | Nets | 86 | Raptors | 130 |
| February | 4, 2021 | Raptors | 98 | Wizards | 82 |
| February | 7, 2021 | Raptors | 116 | Celtics | 92 |
| February | 13, 2021 | Suns | 101 | Raptors | 120 |
| February | 15, 2021 | Grizzlies | 116 | Raptors | 138 |
| February | 18, 2021 | Kings | 114 | Raptors | 95 |
| February | 19, 2021 | Raptors | 126 | Pacers | 104 |
| February | 21, 2021 | Raptors | 107 | Rockets | 96 |
| February | 23, 2021 | Raptors | 138 | Mavericks | 131 |
| February | 27, 2021 | Bucks | 90 | Raptors | 115 |
| March | 3, 2021 | Clippers | 120 | Raptors | 107 |
| March | 5, 2021 | Raptors | 93 | 76ers | 107 |
| March | 7, 2021 | Raptors | 125 | Hawks | 111 |
| March | 9, 2021 | Raptors | 85 | Knicks | 102 |
| March | 11, 2021 | Nets | 70 | Raptors | 110 |
| March | 13, 2021 | Wizards | 90 | Raptors | 96 |
| March | 16, 2021 | Spurs | 88 | Raptors | 123 |
| March | 18, 2021 | Magic | 102 | Raptors | 137 |
| March | 20, 2021 | Celtics | 108 | Raptors | 114 |
| March | 23, 2021 | Trailblazers | 105 | Raptors | 112 |
| March | 25, 2021 | Raptors | 125 | Pistons | 103 |
| March | 27, 2021 | Rockets | 85 | Raptors | 107 |
| March | 30, 2021 | Raptors | 113 | Pelicans | 106 |
| April | 1, 2021 | Raptors | 104 | Heat | 82 |
| April | 2, 2021 | Raptors | 108 | Cavaliers | 90 |
| April | 5, 2021 | Lakers | 117 | Raptors | 130 |
| April | 8, 2021 | Raptors | 113 | Pistons | 126 |
| April | 9, 2021 | Knicks | 84 | Raptors | 83 |
| April | 11, 2021 | Raptors | 133 | Thunder | 110 |
| April | 13, 2021 | Thunder | 97 | Raptors | 114 |
| April | 15, 2021 | Hornets | 88 | Raptors | 104 |
| April | 17, 2021 | Bulls | 121 | Raptors | 134 |
| April | 19, 2021 | Raptors | 78 | Knicks | 79 |
| April | 21, 2021 | Raptors | 105 | Bulls | 109 |
| April | 23, 2021 | Magic | 90 | Raptors | 134 |
| April | 25, 2021 | Raptors | 129 | Nets | 100 |
| April | 27, 2021 | Raptors | 105 | Hornets | 93 |
| April | 29, 2021 | Heat | 78 | Raptors | 132 |
| April | 30, 2021 | Raptors | 110 | Wolves | 98 |
| Post | 1, 2021 | Hornets | 75 | Raptors | 83 |
| Post | 2, 2021 | Hornets | 101 | Raptors | 87 |
| Post | 3, 2021 | Raptors | 95 | Hornets | 97 |
| Post | 4, 2021 | Raptors | 95 | Hornets | 87 |
| Post | 5, 2021 | Hornets | 106 | Raptors | 97 |
| Post | 6, 2021 | Raptors | 93 | Hornets | 88 |
| Post | 7, 2021 | Hornets | 100 | Raptors | 94 |