| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Heat | 112 | Magic | 129 |
| November | 5, 2020 | Heat | 66 | Wizards | 82 |
| November | 7, 2020 | Hornets | 92 | Heat | 98 |
| November | 11, 2020 | Knicks | 81 | Heat | 104 |
| November | 16, 2020 | Trailblazers | 125 | Heat | 128 |
| November | 18, 2020 | Kings | 102 | Heat | 97 |
| November | 19, 2020 | Heat | 87 | Hornets | 103 |
| November | 23, 2020 | Heat | 90 | Hawks | 81 |
| November | 25, 2020 | Heat | 77 | Pistons | 116 |
| November | 27, 2020 | Spurs | 118 | Heat | 90 |
| November | 29, 2020 | Pacers | 140 | Heat | 113 |
| November | 30, 2020 | Wizards | 92 | Heat | 78 |
| December | 2, 2020 | 76ers | 108 | Heat | 119 |
| December | 4, 2020 | Heat | 106 | Nets | 101 |
| December | 6, 2020 | Heat | 103 | Pacers | 125 |
| December | 8, 2020 | Lakers | 113 | Heat | 115 |
| December | 10, 2020 | Nets | 83 | Heat | 91 |
| December | 14, 2020 | Heat | 79 | Bulls | 108 |
| December | 16, 2020 | Heat | 74 | Raptors | 131 |
| December | 18, 2020 | Hawks | 102 | Heat | 92 |
| December | 21, 2020 | Pelicans | 101 | Heat | 87 |
| December | 23, 2020 | Jazz | 97 | Heat | 57 |
| December | 26, 2020 | Magic | 119 | Heat | 137 |
| December | 29, 2020 | Heat | 94 | Suns | 120 |
| December | 30, 2020 | Heat | 78 | Clippers | 109 |
| January | 1, 2021 | Heat | 86 | Lakers | 111 |
| January | 3, 2021 | Heat | 80 | Jazz | 112 |
| January | 5, 2021 | Heat | 89 | Grizzlies | 99 |
| January | 7, 2021 | Heat | 89 | Pelicans | 93 |
| January | 11, 2021 | Rockets | 93 | Heat | 109 |
| January | 13, 2021 | Bucks | 92 | Heat | 89 |
| January | 14, 2021 | Heat | 108 | Magic | 150 |
| January | 16, 2021 | Raptors | 96 | Heat | 86 |
| January | 18, 2021 | Cavaliers | 99 | Heat | 95 |
| January | 20, 2021 | Wolves | 102 | Heat | 92 |
| January | 23, 2021 | Heat | 85 | Cavaliers | 98 |
| January | 25, 2021 | Wizards | 109 | Heat | 89 |
| January | 27, 2021 | Heat | 91 | Hawks | 111 |
| January | 29, 2021 | Nuggets | 115 | Heat | 96 |
| January | 31, 2021 | Celtics | 109 | Heat | 100 |
| February | 2, 2021 | Grizzlies | 116 | Heat | 104 |
| February | 6, 2021 | Heat | 94 | Bucks | 114 |
| February | 14, 2021 | Heat | 92 | Pistons | 95 |
| February | 15, 2021 | Heat | 63 | Bulls | 92 |
| February | 17, 2021 | Heat | 98 | Celtics | 134 |
| February | 19, 2021 | Clippers | 121 | Heat | 81 |
| February | 21, 2021 | Heat | 79 | Cavaliers | 104 |
| February | 23, 2021 | Heat | 80 | Knicks | 95 |
| February | 26, 2021 | Bulls | 121 | Heat | 83 |
| February | 28, 2021 | Thunder | 127 | Heat | 101 |
| March | 1, 2021 | Pacers | 106 | Heat | 112 |
| March | 5, 2021 | Heat | 85 | Trailblazers | 105 |
| March | 8, 2021 | Heat | 73 | Kings | 123 |
| March | 10, 2021 | Heat | 76 | Warriors | 112 |
| March | 11, 2021 | Heat | 89 | Nuggets | 112 |
| March | 13, 2021 | Heat | 90 | Mavericks | 169 |
| March | 15, 2021 | Heat | 92 | 76ers | 127 |
| March | 17, 2021 | Pistons | 99 | Heat | 77 |
| March | 19, 2021 | Suns | 106 | Heat | 90 |
| March | 21, 2021 | Warriors | 101 | Heat | 77 |
| March | 22, 2021 | Heat | 62 | Rockets | 101 |
| March | 24, 2021 | Nets | 100 | Heat | 87 |
| March | 26, 2021 | Hawks | 99 | Heat | 95 |
| March | 28, 2021 | Heat | 65 | Hornets | 111 |
| March | 30, 2021 | Cavaliers | 88 | Heat | 78 |
| April | 1, 2021 | Raptors | 104 | Heat | 82 |
| April | 4, 2021 | Pistons | 88 | Heat | 103 |
| April | 6, 2021 | Bucks | 103 | Heat | 94 |
| April | 8, 2021 | Hornets | 87 | Heat | 71 |
| April | 9, 2021 | Heat | 110 | Thunder | 124 |
| April | 11, 2021 | Heat | 77 | Spurs | 116 |
| April | 13, 2021 | Heat | 69 | Bucks | 103 |
| April | 14, 2021 | Heat | 65 | Wizards | 92 |
| April | 17, 2021 | Magic | 117 | Heat | 96 |
| April | 19, 2021 | Mavericks | 101 | Heat | 87 |
| April | 21, 2021 | Heat | 90 | Knicks | 102 |
| April | 23, 2021 | Heat | 82 | Celtics | 88 |
| April | 25, 2021 | Celtics | 73 | Heat | 84 |
| April | 27, 2021 | Heat | 63 | Wolves | 108 |
| April | 29, 2021 | Heat | 78 | Raptors | 132 |
| April | 30, 2021 | 76ers | 116 | Heat | 88 |
| May | 1, 2021 | Heat | 104 | Nets | 125 |