| month | day | visitor | score | home | score |
|---|
| November | 5, 2020 | Bulls | 103 | 76ers | 118 |
| November | 7, 2020 | Pistons | 112 | Bulls | 134 |
| November | 9, 2020 | Bulls | 124 | Mavericks | 107 |
| November | 11, 2020 | Hornets | 113 | Bulls | 91 |
| November | 14, 2020 | Bulls | 99 | Hornets | 94 |
| November | 15, 2020 | Bulls | 99 | Hawks | 127 |
| November | 18, 2020 | Warriors | 127 | Bulls | 114 |
| November | 20, 2020 | Nuggets | 110 | Bulls | 116 |
| November | 22, 2020 | Pacers | 122 | Bulls | 138 |
| November | 23, 2020 | Rockets | 87 | Bulls | 96 |
| November | 25, 2020 | Bulls | 114 | Knicks | 105 |
| November | 27, 2020 | Bulls | 93 | Pelicans | 110 |
| November | 30, 2020 | Cavaliers | 135 | Bulls | 95 |
| December | 2, 2020 | Mavericks | 107 | Bulls | 119 |
| December | 4, 2020 | Bulls | 129 | Celtics | 96 |
| December | 6, 2020 | Bulls | 97 | Bucks | 128 |
| December | 7, 2020 | Raptors | 111 | Bulls | 108 |
| December | 12, 2020 | Suns | 97 | Bulls | 116 |
| December | 14, 2020 | Heat | 79 | Bulls | 108 |
| December | 15, 2020 | Bulls | 75 | Wolves | 97 |
| December | 17, 2020 | Spurs | 114 | Bulls | 111 |
| December | 19, 2020 | Bulls | 82 | Bucks | 122 |
| December | 21, 2020 | Bulls | 90 | Pistons | 127 |
| December | 22, 2020 | Bulls | 71 | Rockets | 104 |
| December | 26, 2020 | Bulls | 100 | Pacers | 126 |
| December | 29, 2020 | Thunder | 109 | Bulls | 123 |
| December | 30, 2020 | Celtics | 97 | Bulls | 131 |
| January | 1, 2021 | Kings | 85 | Bulls | 89 |
| January | 4, 2021 | Bulls | 124 | Magic | 121 |
| January | 6, 2021 | Bulls | 90 | Spurs | 106 |
| January | 8, 2021 | Bulls | 124 | Thunder | 105 |
| January | 10, 2021 | Nets | 106 | Bulls | 140 |
| January | 12, 2021 | Magic | 106 | Bulls | 126 |
| January | 14, 2021 | Bulls | 114 | Cavaliers | 115 |
| January | 16, 2021 | Wolves | 98 | Bulls | 102 |
| January | 18, 2021 | Bulls | 97 | Wizards | 93 |
| January | 20, 2021 | Bulls | 97 | Raptors | 122 |
| January | 23, 2021 | Magic | 104 | Bulls | 151 |
| January | 25, 2021 | Pacers | 130 | Bulls | 127 |
| January | 27, 2021 | Nets | 97 | Bulls | 111 |
| January | 30, 2021 | Bulls | 98 | Trailblazers | 101 |
| February | 1, 2021 | Bulls | 105 | Warriors | 121 |
| February | 2, 2021 | Bulls | 98 | Jazz | 118 |
| February | 6, 2021 | Bulls | 100 | Lakers | 89 |
| February | 13, 2021 | Bulls | 119 | Nuggets | 106 |
| February | 15, 2021 | Heat | 63 | Bulls | 92 |
| February | 17, 2021 | Bulls | 115 | Cavaliers | 112 |
| February | 19, 2021 | Hawks | 126 | Bulls | 108 |
| February | 21, 2021 | Clippers | 103 | Bulls | 110 |
| February | 23, 2021 | Cavaliers | 116 | Bulls | 106 |
| February | 25, 2021 | Bulls | 120 | Nets | 98 |
| February | 26, 2021 | Bulls | 121 | Heat | 83 |
| March | 1, 2021 | Bulls | 101 | Hornets | 87 |
| March | 6, 2021 | Pelicans | 101 | Bulls | 124 |
| March | 8, 2021 | Bulls | 129 | Nets | 119 |
| March | 9, 2021 | Wizards | 106 | Bulls | 118 |
| March | 11, 2021 | Bucks | 115 | Bulls | 125 |
| March | 13, 2021 | Grizzlies | 105 | Bulls | 135 |
| March | 16, 2021 | Bulls | 120 | Magic | 107 |
| March | 17, 2021 | Celtics | 95 | Bulls | 116 |
| March | 19, 2021 | Bucks | 121 | Bulls | 119 |
| March | 21, 2021 | Bulls | 123 | Grizzlies | 121 |
| March | 23, 2021 | Bulls | 126 | Hawks | 117 |
| March | 25, 2021 | Hawks | 113 | Bulls | 116 |
| March | 27, 2021 | Bulls | 105 | Pacers | 114 |
| March | 28, 2021 | 76ers | 118 | Bulls | 94 |
| March | 30, 2021 | Pistons | 105 | Bulls | 110 |
| April | 1, 2021 | Bulls | 100 | Pistons | 108 |
| April | 3, 2021 | Lakers | 112 | Bulls | 128 |
| April | 6, 2021 | Bulls | 112 | Clippers | 92 |
| April | 8, 2021 | Bulls | 103 | Kings | 85 |
| April | 9, 2021 | Bulls | 124 | Suns | 113 |
| April | 11, 2021 | Wizards | 100 | Bulls | 102 |
| April | 14, 2021 | Jazz | 101 | Bulls | 105 |
| April | 17, 2021 | Bulls | 121 | Raptors | 134 |
| April | 18, 2021 | Trailblazers | 89 | Bulls | 121 |
| April | 21, 2021 | Raptors | 105 | Bulls | 109 |
| April | 23, 2021 | Bulls | 98 | Knicks | 87 |
| April | 25, 2021 | Bulls | 97 | Wizards | 73 |
| April | 28, 2021 | 76ers | 103 | Bulls | 132 |
| April | 30, 2021 | Knicks | 80 | Bulls | 99 |
| May | 1, 2021 | Bulls | 97 | 76ers | 92 |
| Post | 1, 2021 | Bulls | 81 | Pistons | 113 |
| Post | 2, 2021 | Bulls | 87 | Pistons | 119 |
| Post | 3, 2021 | Pistons | 129 | Bulls | 113 |
| Post | 4, 2021 | Pistons | 113 | Bulls | 102 |
| Post | 5, 2021 | Bulls | | Pistons | |
| Post | 6, 2021 | Pistons | | Bulls | |
| Post | 7, 2021 | Bulls | | Pistons | |