| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Rockets | 91 | Mavericks | 74 |
| November | 5, 2020 | Trailblazers | 75 | Mavericks | 122 |
| November | 7, 2020 | Mavericks | 104 | Raptors | 106 |
| November | 8, 2020 | Mavericks | 80 | Pistons | 120 |
| November | 10, 2020 | Mavericks | 88 | Bulls | 103 |
| November | 13, 2020 | Knicks | 79 | Mavericks | 113 |
| November | 15, 2020 | Mavericks | 105 | Nuggets | 90 |
| November | 18, 2020 | Jazz | 100 | Mavericks | 101 |
| November | 20, 2020 | Mavericks | 115 | Pelicans | 83 |
| November | 23, 2020 | Raptors | 106 | Mavericks | 112 |
| November | 25, 2020 | Mavericks | 86 | Grizzlies | 114 |
| November | 27, 2020 | 76ers | 121 | Mavericks | 88 |
| November | 29, 2020 | Mavericks | 101 | Magic | 104 |
| December | 1, 2020 | Mavericks | 119 | Nets | 96 |
| December | 3, 2020 | Mavericks | 91 | Heat | 104 |
| December | 4, 2020 | Mavericks | 105 | Lakers | 102 |
| December | 7, 2020 | Hornets | 84 | Mavericks | 94 |
| December | 9, 2020 | Mavericks | 116 | Warriors | 131 |
| December | 11, 2020 | Heat | 95 | Mavericks | 93 |
| December | 13, 2020 | Mavericks | 121 | Wolves | 116 |
| December | 15, 2020 | Mavericks | 103 | Celtics | 93 |
| December | 18, 2020 | Mavericks | 111 | Bucks | 130 |
| December | 20, 2020 | Suns | 111 | Mavericks | 104 |
| December | 21, 2020 | Spurs | 107 | Mavericks | 112 |
| December | 25, 2020 | Cavaliers | 101 | Mavericks | 116 |
| December | 26, 2020 | Grizzlies | 103 | Mavericks | 112 |
| December | 29, 2020 | Mavericks | 102 | Trailblazers | 104 |
| December | 31, 2020 | Mavericks | 117 | Thunder | 113 |
| January | 2, 2021 | Pacers | 85 | Mavericks | 109 |
| January | 4, 2021 | Mavericks | 80 | Kings | 79 |
| January | 6, 2021 | Nets | 105 | Mavericks | 129 |
| January | 9, 2021 | Mavericks | 99 | Hornets | 86 |
| January | 12, 2021 | Lakers | 80 | Mavericks | 108 |
| January | 14, 2021 | Nuggets | 93 | Mavericks | 117 |
| January | 16, 2021 | Mavericks | 105 | Jazz | 96 |
| January | 17, 2021 | Wizards | 81 | Mavericks | 86 |
| January | 20, 2021 | Mavericks | 98 | Rockets | 100 |
| January | 23, 2021 | Clippers | 103 | Mavericks | 122 |
| January | 25, 2021 | Thunder | 115 | Mavericks | 121 |
| January | 28, 2021 | Mavericks | 120 | Wolves | 100 |
| January | 31, 2021 | Pelicans | 104 | Mavericks | 91 |
| February | 4, 2021 | Mavericks | 95 | Cavaliers | 110 |
| February | 5, 2021 | Mavericks | 118 | 76ers | 109 |
| February | 7, 2021 | Mavericks | 133 | Trailblazers | 110 |
| February | 13, 2021 | Hawks | 97 | Mavericks | 92 |
| February | 16, 2021 | Kings | 85 | Mavericks | 104 |
| February | 17, 2021 | Mavericks | 107 | Suns | 117 |
| February | 19, 2021 | Rockets | 80 | Mavericks | 81 |
| February | 20, 2021 | Mavericks | 114 | Wizards | 103 |
| February | 22, 2021 | Mavericks | 97 | Warriors | 131 |
| February | 24, 2021 | Suns | 111 | Mavericks | 102 |
| February | 27, 2021 | Bulls | 96 | Mavericks | 97 |
| February | 28, 2021 | Mavericks | 85 | Nuggets | 119 |
| March | 2, 2021 | Pistons | 98 | Mavericks | 114 |
| March | 3, 2021 | Warriors | 87 | Mavericks | 100 |
| March | 6, 2021 | Mavericks | 84 | Kings | 110 |
| March | 8, 2021 | Mavericks | 90 | Jazz | 104 |
| March | 10, 2021 | Mavericks | 101 | Thunder | 96 |
| March | 12, 2021 | Celtics | 100 | Mavericks | 137 |
| March | 15, 2021 | Trailblazers | 97 | Mavericks | 122 |
| March | 18, 2021 | Mavericks | 112 | Clippers | 123 |
| March | 19, 2021 | Magic | 111 | Mavericks | 98 |
| March | 21, 2021 | Grizzlies | 107 | Mavericks | 103 |
| March | 24, 2021 | Mavericks | 126 | Pacers | 104 |
| March | 27, 2021 | Mavericks | 94 | Knicks | 85 |
| April | 1, 2021 | Warriors | 104 | Mavericks | 118 |
| April | 2, 2021 | Kings | 91 | Mavericks | 103 |
| April | 4, 2021 | Mavericks | 103 | Suns | 92 |
| April | 6, 2021 | Thunder | 92 | Mavericks | 101 |
| April | 7, 2021 | Lakers | 96 | Mavericks | 102 |
| April | 10, 2021 | Wolves | 111 | Mavericks | 116 |
| April | 12, 2021 | Mavericks | 74 | Rockets | 101 |
| April | 13, 2021 | Mavericks | 77 | Spurs | 89 |
| April | 15, 2021 | Nuggets | 79 | Mavericks | 90 |
| April | 17, 2021 | Clippers | 100 | Mavericks | 72 |
| April | 19, 2021 | Mavericks | 88 | Pelicans | 102 |
| April | 21, 2021 | Mavericks | 110 | Lakers | 100 |
| April | 23, 2021 | Bucks | 102 | Mavericks | 97 |
| April | 26, 2021 | Mavericks | 120 | Grizzlies | 109 |
| April | 28, 2021 | Mavericks | 94 | Hawks | 88 |
| April | 29, 2021 | Spurs | 104 | Mavericks | 95 |
| May | 1, 2021 | Pelicans | 89 | Mavericks | 102 |
| Post | 1, 2021 | Mavericks | 102 | Rockets | 69 |
| Post | 2, 2021 | Mavericks | 89 | Rockets | 105 |
| Post | 3, 2021 | Rockets | 81 | Mavericks | 89 |
| Post | 4, 2021 | Rockets | 96 | Mavericks | 94 |
| Post | 5, 2021 | Mavericks | 84 | Rockets | 101 |
| Post | 6, 2021 | Rockets | 102 | Mavericks | 74 |
| Post | 7, 2021 | Mavericks | | Rockets | |