| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Bucks | 96 | 76ers | 123 |
| November | 5, 2020 | 76ers | 128 | Wizards | 127 |
| November | 7, 2020 | Heat | 109 | 76ers | 111 |
| November | 10, 2020 | 76ers | 99 | Pacers | 95 |
| November | 12, 2020 | 76ers | 112 | Pistons | 117 |
| November | 15, 2020 | Knicks | 113 | 76ers | 139 |
| November | 16, 2020 | Cavaliers | 105 | 76ers | 119 |
| November | 19, 2020 | 76ers | 119 | Hornets | 112 |
| November | 21, 2020 | 76ers | 110 | Magic | 114 |
| November | 24, 2020 | Nuggets | 102 | 76ers | 99 |
| November | 27, 2020 | 76ers | 121 | Mavericks | 88 |
| November | 30, 2020 | 76ers | 124 | Grizzlies | 96 |
| December | 2, 2020 | Pelicans | 113 | 76ers | 117 |
| December | 4, 2020 | Spurs | 124 | 76ers | 102 |
| December | 6, 2020 | Trailblazers | 107 | 76ers | 117 |
| December | 8, 2020 | 76ers | 92 | Pacers | 104 |
| December | 10, 2020 | Kings | 103 | 76ers | 107 |
| December | 12, 2020 | Thunder | 118 | 76ers | 107 |
| December | 14, 2020 | 76ers | 122 | Nets | 102 |
| December | 15, 2020 | Grizzlies | 124 | 76ers | 113 |
| December | 17, 2020 | Rockets | 112 | 76ers | 98 |
| December | 18, 2020 | Clippers | 112 | 76ers | 97 |
| December | 21, 2020 | Wolves | 121 | 76ers | 110 |
| December | 22, 2020 | Warriors | 98 | 76ers | 104 |
| December | 25, 2020 | Celtics | 104 | 76ers | 116 |
| December | 27, 2020 | 76ers | 95 | Bulls | 108 |
| December | 30, 2020 | 76ers | 101 | Raptors | 117 |
| January | 1, 2021 | Hornets | 98 | 76ers | 102 |
| January | 3, 2021 | Jazz | 98 | 76ers | 90 |
| January | 5, 2021 | 76ers | 110 | Pelicans | 117 |
| January | 8, 2021 | 76ers | 101 | Nuggets | 92 |
| January | 10, 2021 | Bulls | 115 | 76ers | 104 |
| January | 12, 2021 | 76ers | 109 | Thunder | 122 |
| January | 13, 2021 | 76ers | 110 | Kings | 104 |
| January | 15, 2021 | Suns | 104 | 76ers | 113 |
| January | 18, 2021 | 76ers | 122 | Celtics | 91 |
| January | 19, 2021 | Lakers | 108 | 76ers | 90 |
| January | 21, 2021 | 76ers | 113 | Warriors | 105 |
| January | 24, 2021 | 76ers | 113 | Hawks | 96 |
| January | 26, 2021 | Raptors | 117 | 76ers | 110 |
| January | 29, 2021 | 76ers | 96 | Cavaliers | 102 |
| January | 31, 2021 | Magic | 100 | 76ers | 101 |
| February | 2, 2021 | Wizards | 97 | 76ers | 108 |
| February | 4, 2021 | 76ers | 104 | Spurs | 122 |
| February | 5, 2021 | Mavericks | 118 | 76ers | 109 |
| February | 13, 2021 | Pacers | 97 | 76ers | 123 |
| February | 14, 2021 | Nets | 118 | 76ers | 134 |
| February | 17, 2021 | 76ers | 120 | Clippers | 102 |
| February | 18, 2021 | 76ers | 122 | Trailblazers | 101 |
| February | 20, 2021 | 76ers | 110 | Jazz | 127 |
| February | 23, 2021 | Pacers | 96 | 76ers | 113 |
| February | 25, 2021 | Heat | 111 | 76ers | 120 |
| February | 27, 2021 | 76ers | 120 | Knicks | 116 |
| March | 1, 2021 | Pistons | 93 | 76ers | 130 |
| March | 4, 2021 | Bucks | 98 | 76ers | 112 |
| March | 6, 2021 | 76ers | 90 | Wolves | 135 |
| March | 9, 2021 | Celtics | 90 | 76ers | 116 |
| March | 11, 2021 | 76ers | 95 | Raptors | 116 |
| March | 12, 2021 | 76ers | 89 | Cavaliers | 108 |
| March | 15, 2021 | Wizards | 93 | 76ers | 107 |
| March | 17, 2021 | 76ers | 119 | Hawks | 103 |
| March | 18, 2021 | 76ers | 114 | Wizards | 108 |
| March | 20, 2021 | Bulls | 100 | 76ers | 95 |
| March | 22, 2021 | 76ers | 122 | Lakers | 91 |
| March | 25, 2021 | Pistons | 114 | 76ers | 106 |
| March | 27, 2021 | Hawks | 113 | 76ers | 106 |
| March | 30, 2021 | 76ers | 98 | Rockets | 110 |
| April | 2, 2021 | Nets | 107 | 76ers | 143 |
| April | 5, 2021 | 76ers | 131 | Heat | 95 |
| April | 7, 2021 | 76ers | 92 | Hornets | 105 |
| April | 10, 2021 | 76ers | 112 | Bulls | 108 |
| April | 12, 2021 | Raptors | 105 | 76ers | 119 |
| April | 14, 2021 | 76ers | 113 | Celtics | 101 |
| April | 16, 2021 | 76ers | 108 | Heat | 122 |
| April | 18, 2021 | 76ers | 88 | Knicks | 108 |
| April | 19, 2021 | Cavaliers | 123 | 76ers | 111 |
| April | 21, 2021 | 76ers | 96 | Bucks | 134 |
| April | 24, 2021 | 76ers | 110 | Suns | 93 |
| April | 26, 2021 | Magic | 101 | 76ers | 120 |
| April | 27, 2021 | 76ers | 109 | Nets | 104 |
| April | 30, 2021 | 76ers | 112 | Pistons | 120 |
| May | 1, 2021 | Hawks | 111 | 76ers | 137 |
| Post | 1, 2021 | Hawks | 102 | 76ers | 117 |
| Post | 2, 2021 | Hawks | 112 | 76ers | 115 |
| Post | 3, 2021 | 76ers | 92 | Hawks | 116 |
| Post | 4, 2021 | 76ers | 104 | Hawks | 101 |
| Post | 5, 2021 | Hawks | 102 | 76ers | 112 |
| Post | 6, 2021 | 76ers | | Hawks | |
| Post | 7, 2021 | Hawks | | 76ers | |
| Post | 8, 2021 | 76ers | 117 | Raptors | 103 |
| Post | 9, 2021 | 76ers | 104 | Raptors | 107 |
| Post | 10, 2021 | Raptors | 103 | 76ers | 111 |
| Post | 11, 2021 | Raptors | 122 | 76ers | 108 |
| Post | 12, 2021 | 76ers | 110 | Raptors | 111 |
| Post | 13, 2021 | Raptors | 108 | 76ers | 96 |
| Post | 14, 2021 | 76ers | | Raptors | |