| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Magic | 99 | Raptors | 116 |
| November | 6, 2020 | Bulls | 101 | Raptors | 104 |
| November | 7, 2020 | Mavericks | 88 | Raptors | 124 |
| November | 10, 2020 | Hawks | 108 | Raptors | 114 |
| November | 11, 2020 | Raptors | 117 | Warriors | 98 |
| November | 13, 2020 | Pelicans | 102 | Raptors | 117 |
| November | 15, 2020 | Thunder | 110 | Raptors | 114 |
| November | 16, 2020 | Wolves | 90 | Raptors | 98 |
| November | 19, 2020 | Pistons | 119 | Raptors | 101 |
| November | 21, 2020 | Raptors | 129 | Lakers | 126 |
| November | 22, 2020 | Cavaliers | 113 | Raptors | 107 |
| November | 23, 2020 | Raptors | 129 | Mavericks | 95 |
| November | 25, 2020 | Hornets | 69 | Raptors | 76 |
| November | 27, 2020 | Nuggets | 101 | Raptors | 110 |
| November | 29, 2020 | Hornets | 93 | Raptors | 80 |
| December | 2, 2020 | Raptors | 134 | Bulls | 104 |
| December | 3, 2020 | Raptors | 120 | Nuggets | 103 |
| December | 5, 2020 | Bucks | 121 | Raptors | 118 |
| December | 6, 2020 | Knicks | 95 | Raptors | 120 |
| December | 8, 2020 | Trailblazers | 115 | Raptors | 133 |
| December | 9, 2020 | Raptors | 106 | Thunder | 102 |
| December | 10, 2020 | Raptors | 106 | Pistons | 128 |
| December | 13, 2020 | Raptors | 103 | Pelicans | 127 |
| December | 16, 2020 | Raptors | 97 | Magic | 112 |
| December | 17, 2020 | Raptors | 115 | Pacers | 100 |
| December | 20, 2020 | Raptors | 100 | Jazz | 94 |
| December | 22, 2020 | Raptors | 124 | Celtics | 127 |
| December | 23, 2020 | Raptors | 121 | Wizards | 92 |
| December | 28, 2020 | Raptors | 101 | Heat | 108 |
| December | 30, 2020 | 76ers | 105 | Raptors | 111 |
| January | 1, 2021 | Jazz | 94 | Raptors | 109 |
| January | 4, 2021 | Lakers | 111 | Raptors | 119 |
| January | 5, 2021 | Nets | 107 | Raptors | 119 |
| January | 8, 2021 | Raptors | 102 | Clippers | 90 |
| January | 10, 2021 | Pacers | 75 | Raptors | 90 |
| January | 12, 2021 | Wizards | 103 | Raptors | 113 |
| January | 13, 2021 | Warriors | 100 | Raptors | 83 |
| January | 15, 2021 | Wizards | 91 | Raptors | 106 |
| January | 17, 2021 | Raptors | 116 | Knicks | 87 |
| January | 18, 2021 | Raptors | 114 | Grizzlies | 99 |
| January | 21, 2021 | Raptors | 115 | Rockets | 105 |
| January | 23, 2021 | Pistons | 128 | Raptors | 127 |
| January | 26, 2021 | Raptors | 96 | 76ers | 108 |
| January | 27, 2021 | Heat | 122 | Raptors | 113 |
| January | 30, 2021 | Grizzlies | 116 | Raptors | 91 |
| February | 1, 2021 | Raptors | 86 | Kings | 90 |
| February | 2, 2021 | Raptors | 114 | Pistons | 119 |
| February | 4, 2021 | Nets | 102 | Raptors | 131 |
| February | 6, 2021 | Rockets | 108 | Raptors | 105 |
| February | 13, 2021 | Knicks | 89 | Raptors | 127 |
| February | 16, 2021 | Raptors | 103 | Hawks | 99 |
| February | 20, 2021 | Raptors | 110 | Cavaliers | 125 |
| February | 22, 2021 | Hawks | 91 | Raptors | 105 |
| February | 23, 2021 | Raptors | 131 | Cavaliers | 74 |
| February | 25, 2021 | Raptors | 106 | Pacers | 119 |
| February | 26, 2021 | Kings | 86 | Raptors | 101 |
| March | 1, 2021 | Raptors | 119 | Trailblazers | 112 |
| March | 4, 2021 | Spurs | 129 | Raptors | 134 |
| March | 7, 2021 | Raptors | 122 | Celtics | 103 |
| March | 9, 2021 | Pacers | 103 | Raptors | 77 |
| March | 11, 2021 | 76ers | 92 | Raptors | 108 |
| March | 15, 2021 | Raptors | 113 | Magic | 125 |
| March | 18, 2021 | Raptors | 92 | Hornets | 86 |
| March | 21, 2021 | Clippers | 106 | Raptors | 116 |
| March | 24, 2021 | Raptors | 110 | Spurs | 116 |
| March | 28, 2021 | Raptors | 105 | Bucks | 89 |
| March | 30, 2021 | Heat | 103 | Raptors | 113 |
| April | 2, 2021 | Suns | 86 | Raptors | 116 |
| April | 4, 2021 | Raptors | 117 | Hawks | 91 |
| April | 6, 2021 | Bulls | 96 | Raptors | 112 |
| April | 9, 2021 | Celtics | 97 | Raptors | 113 |
| April | 11, 2021 | Raptors | 90 | Bucks | 81 |
| April | 12, 2021 | Raptors | 66 | 76ers | 77 |
| April | 14, 2021 | Raptors | 73 | Bulls | 115 |
| April | 17, 2021 | Raptors | 96 | Suns | 120 |
| April | 18, 2021 | Magic | 89 | Raptors | 103 |
| April | 21, 2021 | Raptors | 101 | Wolves | 91 |
| April | 24, 2021 | Raptors | 118 | Wizards | 113 |
| April | 25, 2021 | Raptors | 115 | Knicks | 104 |
| April | 27, 2021 | Cavaliers | 100 | Raptors | 111 |
| April | 30, 2021 | Raptors | 119 | Heat | 109 |
| May | 1, 2021 | Raptors | 128 | Nets | 107 |
| Post | 1, 2021 | Hawks | 91 | Raptors | 107 |
| Post | 2, 2021 | Hawks | 105 | Raptors | 124 |
| Post | 3, 2021 | Raptors | 113 | Hawks | 104 |
| Post | 4, 2021 | Raptors | 106 | Hawks | 102 |
| Post | 5, 2021 | Hawks | | Raptors | |
| Post | 6, 2021 | Raptors | | Hawks | |
| Post | 7, 2021 | Hawks | | Raptors | |
| Post | 8, 2021 | 76ers | 114 | Raptors | 121 |
| Post | 9, 2021 | 76ers | 110 | Raptors | 112 |
| Post | 10, 2021 | Raptors | 111 | 76ers | 109 |
| Post | 11, 2021 | Raptors | 99 | 76ers | 87 |
| Post | 12, 2021 | 76ers | | Raptors | |
| Post | 13, 2021 | Raptors | | 76ers | |
| Post | 14, 2021 | 76ers | | Raptors | |
| Post | 15, 2021 | Raptors | 94 | Pistons | 87 |
| Post | 16, 2021 | Raptors | 107 | Pistons | 93 |
| Post | 17, 2021 | Pistons | 108 | Raptors | 104 |
| Post | 18, 2021 | Pistons | 99 | Raptors | 88 |
| Post | 19, 2021 | Raptors | 92 | Pistons | 112 |
| Post | 20, 2021 | Pistons | 113 | Raptors | 101 |
| Post | 21, 2021 | Raptors | | Pistons | |