| month | day | visitor | score | home | score |
|---|
| November | 3, 2020 | Bucks | 94 | 76ers | 97 |
| November | 5, 2020 | 76ers | 107 | Wizards | 115 |
| November | 7, 2020 | Heat | 94 | 76ers | 124 |
| November | 10, 2020 | 76ers | 107 | Pacers | 110 |
| November | 12, 2020 | 76ers | 120 | Pistons | 133 |
| November | 15, 2020 | Knicks | 103 | 76ers | 109 |
| November | 16, 2020 | Cavaliers | 95 | 76ers | 116 |
| November | 19, 2020 | 76ers | 100 | Hornets | 91 |
| November | 21, 2020 | 76ers | 116 | Magic | 131 |
| November | 24, 2020 | Nuggets | 112 | 76ers | 115 |
| November | 27, 2020 | 76ers | 111 | Mavericks | 105 |
| November | 30, 2020 | 76ers | 106 | Grizzlies | 116 |
| December | 2, 2020 | Pelicans | 118 | 76ers | 98 |
| December | 4, 2020 | Spurs | 110 | 76ers | 136 |
| December | 6, 2020 | Trailblazers | 107 | 76ers | 110 |
| December | 8, 2020 | 76ers | 121 | Pacers | 132 |
| December | 10, 2020 | Kings | 101 | 76ers | 104 |
| December | 12, 2020 | Thunder | 110 | 76ers | 125 |
| December | 14, 2020 | 76ers | 106 | Nets | 104 |
| December | 15, 2020 | Grizzlies | 84 | 76ers | 112 |
| December | 17, 2020 | Rockets | 94 | 76ers | 104 |
| December | 18, 2020 | Clippers | 104 | 76ers | 136 |
| December | 21, 2020 | Wolves | 100 | 76ers | 122 |
| December | 22, 2020 | Warriors | 114 | 76ers | 104 |
| December | 25, 2020 | Celtics | 116 | 76ers | 117 |
| December | 27, 2020 | 76ers | 99 | Bulls | 81 |
| December | 30, 2020 | 76ers | 105 | Raptors | 111 |
| January | 1, 2021 | Hornets | 84 | 76ers | 105 |
| January | 3, 2021 | Jazz | 99 | 76ers | 102 |
| January | 5, 2021 | 76ers | 115 | Pelicans | 97 |
| January | 8, 2021 | 76ers | 104 | Nuggets | 124 |
| January | 10, 2021 | Bulls | 112 | 76ers | 107 |
| January | 12, 2021 | 76ers | 130 | Thunder | 98 |
| January | 13, 2021 | 76ers | 66 | Kings | 93 |
| January | 15, 2021 | Suns | 110 | 76ers | 120 |
| January | 18, 2021 | 76ers | 106 | Celtics | 120 |
| January | 19, 2021 | Lakers | 113 | 76ers | 108 |
| January | 21, 2021 | 76ers | 94 | Warriors | 116 |
| January | 24, 2021 | 76ers | 100 | Hawks | 92 |
| January | 26, 2021 | Raptors | 96 | 76ers | 108 |
| January | 29, 2021 | 76ers | 119 | Cavaliers | 104 |
| January | 31, 2021 | Magic | 118 | 76ers | 119 |
| February | 2, 2021 | Wizards | 113 | 76ers | 120 |
| February | 4, 2021 | 76ers | 116 | Spurs | 137 |
| February | 5, 2021 | Mavericks | 100 | 76ers | 91 |
| February | 13, 2021 | Pacers | 103 | 76ers | 100 |
| February | 14, 2021 | Nets | 107 | 76ers | 95 |
| February | 17, 2021 | 76ers | 106 | Clippers | 111 |
| February | 18, 2021 | 76ers | 133 | Trailblazers | 103 |
| February | 20, 2021 | 76ers | 104 | Jazz | 114 |
| February | 23, 2021 | Pacers | 116 | 76ers | 104 |
| February | 25, 2021 | Heat | 125 | 76ers | 128 |
| February | 27, 2021 | 76ers | 110 | Knicks | 98 |
| March | 1, 2021 | Pistons | 124 | 76ers | 111 |
| March | 4, 2021 | Bucks | 79 | 76ers | 101 |
| March | 6, 2021 | 76ers | 116 | Wolves | 114 |
| March | 9, 2021 | Celtics | 121 | 76ers | 105 |
| March | 11, 2021 | 76ers | 92 | Raptors | 108 |
| March | 12, 2021 | 76ers | 110 | Cavaliers | 109 |
| March | 15, 2021 | Wizards | 94 | 76ers | 95 |
| March | 17, 2021 | 76ers | 111 | Hawks | 102 |
| March | 18, 2021 | 76ers | 109 | Wizards | 115 |
| March | 20, 2021 | Bulls | 108 | 76ers | 107 |
| March | 22, 2021 | 76ers | 78 | Lakers | 123 |
| March | 25, 2021 | Pistons | 111 | 76ers | 98 |
| March | 27, 2021 | Hawks | 83 | 76ers | 88 |
| March | 30, 2021 | 76ers | 74 | Rockets | 104 |
| April | 2, 2021 | Nets | 109 | 76ers | 116 |
| April | 5, 2021 | 76ers | 106 | Heat | 92 |
| April | 7, 2021 | 76ers | 87 | Hornets | 90 |
| April | 10, 2021 | 76ers | 80 | Bulls | 106 |
| April | 12, 2021 | Raptors | 66 | 76ers | 77 |
| April | 14, 2021 | 76ers | 95 | Celtics | 126 |
| April | 16, 2021 | 76ers | 82 | Heat | 137 |
| April | 18, 2021 | 76ers | 93 | Knicks | 99 |
| April | 19, 2021 | Cavaliers | 112 | 76ers | 113 |
| April | 21, 2021 | 76ers | 76 | Bucks | 96 |
| April | 24, 2021 | 76ers | 107 | Suns | 128 |
| April | 26, 2021 | Magic | 111 | 76ers | 127 |
| April | 27, 2021 | 76ers | 88 | Nets | 109 |
| April | 30, 2021 | 76ers | 112 | Pistons | 122 |
| May | 1, 2021 | Hawks | 98 | 76ers | 119 |
| Post | 1, 2021 | 76ers | 96 | Magic | 114 |
| Post | 2, 2021 | 76ers | 116 | Magic | 135 |
| Post | 3, 2021 | Magic | 113 | 76ers | 119 |
| Post | 4, 2021 | Magic | 116 | 76ers | 136 |
| Post | 5, 2021 | 76ers | 112 | Magic | 103 |
| Post | 6, 2021 | Magic | 129 | 76ers | 127 |
| Post | 7, 2021 | 76ers | 125 | Magic | 120 |
| Post | 8, 2021 | 76ers | 114 | Raptors | 121 |
| Post | 9, 2021 | 76ers | 110 | Raptors | 112 |
| Post | 10, 2021 | Raptors | 111 | 76ers | 109 |
| Post | 11, 2021 | Raptors | 99 | 76ers | 87 |
| Post | 12, 2021 | 76ers | | Raptors | |
| Post | 13, 2021 | Raptors | | 76ers | |
| Post | 14, 2021 | 76ers | | Raptors | |