| month | day | visitor | score | home | score |
|---|
| November | 2, 2010 | Clippers | 110 | Lakers | 105 |
| November | 5, 2010 | Lakers | 105 | Jazz | 131 |
| November | 7, 2010 | Thunder | 120 | Lakers | 134 |
| November | 10, 2010 | Trailblazers | 120 | Lakers | 117 |
| November | 12, 2010 | Lakers | 109 | Knicks | 108 |
| November | 15, 2010 | Lakers | 114 | Nets | 119 |
| November | 17, 2010 | Nuggets | 106 | Lakers | 143 |
| November | 19, 2010 | Lakers | 102 | Spurs | 129 |
| November | 21, 2010 | Raptors | 106 | Lakers | 103 |
| November | 24, 2010 | Lakers | 122 | Warriors | 116 |
| November | 26, 2010 | Wolves | 114 | Lakers | 133 |
| November | 28, 2010 | Lakers | 108 | Celtics | 111 |
| November | 30, 2010 | Lakers | 105 | Wizards | 114 |
| December | 2, 2010 | Lakers | 82 | Kings | 92 |
| December | 4, 2010 | Mavericks | 109 | Lakers | 126 |
| December | 7, 2010 | Pistons | 122 | Lakers | 102 |
| December | 8, 2010 | Knicks | 96 | Lakers | 117 |
| December | 10, 2010 | Grizzlies | 91 | Lakers | 98 |
| December | 12, 2010 | Lakers | 129 | Suns | 108 |
| December | 15, 2010 | Pacers | 110 | Lakers | 103 |
| December | 17, 2010 | Magic | 113 | Lakers | 132 |
| December | 18, 2010 | Lakers | 113 | Jazz | 124 |
| December | 20, 2010 | Cavaliers | 106 | Lakers | 90 |
| December | 22, 2010 | Lakers | 112 | Thunder | 127 |
| December | 25, 2010 | Spurs | 107 | Lakers | 103 |
| December | 28, 2010 | Pelicans | 92 | Lakers | 123 |
| December | 30, 2010 | Lakers | 113 | Hornets | 111 |
| January | 1, 2011 | Lakers | 125 | Hawks | 129 |
| January | 4, 2011 | Lakers | 118 | Raptors | 106 |
| January | 6, 2011 | Rockets | 110 | Lakers | 109 |
| January | 8, 2011 | Lakers | 131 | Trailblazers | 124 |
| January | 10, 2011 | Heat | 108 | Lakers | 119 |
| January | 12, 2011 | Lakers | 110 | Mavericks | 107 |
| January | 16, 2011 | Lakers | 124 | Bulls | 112 |
| January | 19, 2011 | Lakers | 101 | 76ers | 112 |
| January | 20, 2011 | Lakers | 93 | Bucks | 102 |
| January | 21, 2011 | Hawks | 94 | Lakers | 112 |
| January | 24, 2011 | Spurs | 114 | Lakers | 104 |
| January | 27, 2011 | Lakers | 113 | Rockets | 123 |
| January | 28, 2011 | Kings | 114 | Lakers | 122 |
| January | 31, 2011 | Lakers | 130 | Grizzlies | 110 |
| February | 1, 2011 | Lakers | 137 | Nuggets | 121 |
| February | 4, 2011 | Lakers | 117 | Trailblazers | 110 |
| February | 5, 2011 | Lakers | 114 | Clippers | 106 |
| February | 7, 2011 | Hornets | 108 | Lakers | 127 |
| February | 14, 2011 | Suns | 126 | Lakers | 103 |
| February | 17, 2011 | Lakers | 93 | Cavaliers | 115 |
| February | 18, 2011 | Lakers | 139 | Pistons | 107 |
| February | 20, 2011 | Celtics | 111 | Lakers | 131 |
| February | 22, 2011 | Lakers | 110 | Pelicans | 117 |
| February | 24, 2011 | Warriors | 115 | Lakers | 133 |
| February | 26, 2011 | Lakers | 125 | Wolves | 128 |
| February | 28, 2011 | Wizards | 108 | Lakers | 107 |
| March | 2, 2011 | Lakers | 105 | Heat | 120 |
| March | 3, 2011 | Lakers | 105 | Magic | 112 |
| March | 6, 2011 | Trailblazers | 105 | Lakers | 113 |
| March | 7, 2011 | Lakers | 92 | Thunder | 126 |
| March | 9, 2011 | Pelicans | 129 | Lakers | 139 |
| March | 12, 2011 | Lakers | 108 | Pacers | 122 |
| March | 15, 2011 | Lakers | 97 | Spurs | 137 |
| March | 16, 2011 | Kings | 115 | Lakers | 103 |
| March | 19, 2011 | Lakers | 116 | Warriors | 115 |
| March | 22, 2011 | 76ers | 90 | Lakers | 116 |
| March | 24, 2011 | Suns | 97 | Lakers | 118 |
| March | 27, 2011 | Rockets | 98 | Lakers | 117 |
| March | 28, 2011 | Lakers | 118 | Nuggets | 112 |
| March | 30, 2011 | Jazz | 101 | Lakers | 116 |
| April | 1, 2011 | Lakers | 114 | Wolves | 113 |
| April | 2, 2011 | Lakers | 109 | Rockets | 107 |
| April | 4, 2011 | Thunder | 123 | Lakers | 131 |
| April | 7, 2011 | Lakers | 122 | Mavericks | 97 |
| April | 10, 2011 | Nets | 93 | Lakers | 126 |
| April | 13, 2011 | Lakers | 83 | Kings | 110 |
| April | 14, 2011 | Grizzlies | 108 | Lakers | 135 |
| April | 16, 2011 | Bucks | 98 | Lakers | 115 |
| April | 19, 2011 | Bulls | 125 | Lakers | 113 |
| April | 21, 2011 | Mavericks | 117 | Lakers | 105 |
| April | 24, 2011 | Lakers | 93 | Clippers | 113 |
| April | 25, 2011 | Lakers | 131 | Pelicans | 112 |
| April | 27, 2011 | Nuggets | 107 | Lakers | 131 |
| April | 28, 2011 | Warriors | 95 | Lakers | 110 |
| May | 1, 2011 | Wolves | 133 | Lakers | 117 |
| Post | 1, 2011 | Lakers | 86 | Warriors | 122 |
| Post | 2, 2011 | Lakers | 92 | Warriors | 115 |
| Post | 3, 2011 | Warriors | 121 | Lakers | 113 |
| Post | 4, 2011 | Warriors | 106 | Lakers | 98 |
| Post | 5, 2011 | Lakers | | Warriors | |
| Post | 6, 2011 | Warriors | | Lakers | |
| Post | 7, 2011 | Lakers | | Warriors | |