| month | day | visitor | score | home | score |
|---|
| November | 4, 2009 | Wolves | 93 | Mavericks | 84 |
| November | 5, 2009 | Blazers | 100 | Mavericks | 96 |
| November | 6, 2009 | Mavericks | 78 | Celtics | 91 |
| November | 8, 2009 | Hornets | 79 | Mavericks | 77 |
| November | 13, 2009 | Mavericks | 99 | Spurs | 90 |
| November | 14, 2009 | Clippers | 95 | Mavericks | 59 |
| November | 16, 2009 | Spurs | 116 | Mavericks | 101 |
| November | 17, 2009 | 76ers | 100 | Mavericks | 86 |
| November | 18, 2009 | Mavericks | 84 | Grizzlies | 92 |
| November | 19, 2009 | Heat | 83 | Mavericks | 82 |
| November | 21, 2009 | Mavericks | 69 | Knicks | 86 |
| November | 22, 2009 | Mavericks | 66 | Suns | 108 |
| November | 24, 2009 | Mavericks | 75 | Blazers | 100 |
| November | 26, 2009 | Clippers | 76 | Mavericks | 84 |
| November | 27, 2009 | Kings | 92 | Mavericks | 77 |
| November | 30, 2009 | Mavericks | 74 | Rockets | 108 |
| December | 4, 2009 | Mavericks | 81 | Bobcats | 87 |
| December | 7, 2009 | Wizards | 97 | Mavericks | 93 |
| December | 8, 2009 | Mavericks | 88 | Hornets | 84 |
| December | 15, 2009 | Rockets | 90 | Mavericks | 75 |
| December | 16, 2009 | Mavericks | 94 | Spurs | 111 |
| December | 18, 2009 | Mavericks | 88 | Wolves | 102 |
| December | 22, 2009 | Mavericks | 82 | Nuggets | 111 |
| December | 23, 2009 | Mavericks | 73 | Bucks | 99 |
| December | 26, 2009 | Mavericks | 84 | Warriors | 90 |
| December | 27, 2009 | Knicks | 93 | Mavericks | 92 |
| December | 30, 2009 | Mavericks | 94 | Thunder | 113 |
| January | 1, 2010 | Grizzlies | 90 | Mavericks | 105 |
| January | 2, 2010 | Mavericks | 83 | Suns | 97 |
| January | 4, 2010 | Thunder | 108 | Mavericks | 89 |
| January | 5, 2010 | Wolves | 79 | Mavericks | 83 |
| January | 7, 2010 | Mavericks | 100 | Pacers | 95 |
| January | 9, 2010 | Mavericks | 77 | Kings | 78 |
| January | 10, 2010 | Warriors | 107 | Mavericks | 70 |
| January | 12, 2010 | Celtics | 99 | Mavericks | 87 |
| January | 13, 2010 | Lakers | 113 | Mavericks | 90 |
| January | 14, 2010 | Mavericks | 99 | Pistons | 96 |
| January | 20, 2010 | Suns | 98 | Mavericks | 87 |
| January | 22, 2010 | Kings | 84 | Mavericks | 67 |
| January | 23, 2010 | Mavericks | 70 | Wolves | 97 |
| January | 25, 2010 | Mavericks | 79 | Lakers | 99 |
| January | 26, 2010 | Nuggets | 86 | Mavericks | 85 |
| January | 28, 2010 | Jazz | 100 | Mavericks | 81 |
| January | 29, 2010 | Mavericks | 81 | Jazz | 113 |
| January | 30, 2010 | Lakers | 92 | Mavericks | 103 |
| February | 2, 2010 | Grizzlies | 97 | Mavericks | 92 |
| February | 4, 2010 | Bucks | 100 | Mavericks | 73 |
| February | 5, 2010 | Mavericks | 62 | Bulls | 96 |
| February | 14, 2010 | Mavericks | 78 | Rockets | 83 |
| February | 18, 2010 | Raptors | 86 | Mavericks | 85 |
| February | 20, 2010 | Warriors | 95 | Mavericks | 81 |
| February | 23, 2010 | Magic | 109 | Mavericks | 89 |
| February | 24, 2010 | Hornets | 95 | Mavericks | 88 |
| February | 25, 2010 | Pacers | 116 | Mavericks | 104 |
| February | 26, 2010 | Mavericks | 73 | Wizards | 94 |
| February | 27, 2010 | Bulls | 94 | Mavericks | 85 |
| March | 6, 2010 | Mavericks | 83 | Thunder | 104 |
| March | 11, 2010 | Mavericks | 76 | Lakers | 98 |
| March | 12, 2010 | Mavericks | 69 | Nuggets | 93 |
| March | 13, 2010 | Mavericks | 76 | 76ers | 106 |
| March | 14, 2010 | Mavericks | 77 | Kings | 88 |
| March | 18, 2010 | Thunder | 80 | Mavericks | 59 |
| March | 21, 2010 | Mavericks | 73 | Nets | 83 |
| March | 23, 2010 | Mavericks | 76 | Clippers | 94 |
| March | 24, 2010 | Pistons | 98 | Mavericks | 92 |
| March | 29, 2010 | Jazz | 74 | Mavericks | 80 |
| March | 30, 2010 | Nets | 93 | Mavericks | 75 |
| April | 1, 2010 | Mavericks | 76 | Magic | 100 |
| April | 2, 2010 | Bobcats | 87 | Mavericks | 80 |
| April | 5, 2010 | Mavericks | 72 | Raptors | 85 |
| April | 6, 2010 | Blazers | 78 | Mavericks | 80 |
| April | 10, 2010 | Mavericks | 93 | Hornets | 96 |
| April | 13, 2010 | Mavericks | 80 | Clippers | 87 |
| April | 17, 2010 | Mavericks | 76 | Heat | 116 |
| April | 18, 2010 | Spurs | 95 | Mavericks | 102 |
| April | 20, 2010 | Mavericks | 69 | Hawks | 113 |
| April | 22, 2010 | Mavericks | 79 | Cavaliers | 103 |
| April | 24, 2010 | Suns | 106 | Mavericks | 76 |
| April | 25, 2010 | Mavericks | 102 | Warriors | 90 |
| April | 26, 2010 | Cavaliers | 97 | Mavericks | 99 |
| April | 28, 2010 | Mavericks | 86 | Blazers | 96 |
| May | 3, 2010 | Hawks | 96 | Mavericks | 97 |