| month | day | visitor | score | home | score |
|---|
| November | 2, 2010 | Magic | 96 | Trailblazers | 107 |
| November | 4, 2010 | Pacers | 93 | Trailblazers | 113 |
| November | 6, 2010 | Trailblazers | 88 | Nets | 131 |
| November | 7, 2010 | Suns | 118 | Trailblazers | 89 |
| November | 10, 2010 | Nuggets | 83 | Trailblazers | 90 |
| November | 12, 2010 | Thunder | 111 | Trailblazers | 112 |
| November | 13, 2010 | Wizards | 119 | Trailblazers | 110 |
| November | 15, 2010 | Trailblazers | 98 | Hawks | 110 |
| November | 18, 2010 | Bucks | 102 | Trailblazers | 117 |
| November | 21, 2010 | Trailblazers | 114 | Spurs | 127 |
| November | 22, 2010 | Jazz | 106 | Trailblazers | 103 |
| November | 26, 2010 | Warriors | 108 | Trailblazers | 106 |
| November | 29, 2010 | Trailblazers | 100 | Thunder | 113 |
| December | 1, 2010 | Grizzlies | 94 | Trailblazers | 104 |
| December | 5, 2010 | Clippers | 97 | Trailblazers | 111 |
| December | 7, 2010 | Cavaliers | 86 | Trailblazers | 103 |
| December | 8, 2010 | Knicks | 108 | Trailblazers | 102 |
| December | 11, 2010 | Trailblazers | 113 | Jazz | 117 |
| December | 14, 2010 | Trailblazers | 105 | Pacers | 91 |
| December | 15, 2010 | Kings | 102 | Trailblazers | 120 |
| December | 16, 2010 | Rockets | 83 | Trailblazers | 90 |
| December | 18, 2010 | Trailblazers | 108 | Cavaliers | 95 |
| December | 19, 2010 | Pistons | 110 | Trailblazers | 92 |
| December | 22, 2010 | Trailblazers | 103 | Jazz | 106 |
| December | 23, 2010 | Spurs | 106 | Trailblazers | 91 |
| December | 26, 2010 | Trailblazers | 98 | Lakers | 101 |
| December | 28, 2010 | Trailblazers | 117 | Mavericks | 119 |
| December | 29, 2010 | Mavericks | 115 | Trailblazers | 116 |
| December | 31, 2010 | Hornets | 103 | Trailblazers | 114 |
| January | 3, 2011 | Trailblazers | 106 | Heat | 99 |
| January | 5, 2011 | Trailblazers | 101 | Wizards | 97 |
| January | 8, 2011 | Trailblazers | 112 | Celtics | 80 |
| January | 9, 2011 | Trailblazers | 102 | Bulls | 114 |
| January | 12, 2011 | Raptors | 73 | Trailblazers | 115 |
| January | 13, 2011 | Trailblazers | 99 | Nuggets | 120 |
| January | 15, 2011 | Trailblazers | 91 | Grizzlies | 97 |
| January | 17, 2011 | Trailblazers | 99 | Lakers | 105 |
| January | 20, 2011 | 76ers | 99 | Trailblazers | 96 |
| January | 21, 2011 | Warriors | 88 | Trailblazers | 92 |
| January | 23, 2011 | Suns | 84 | Trailblazers | 83 |
| January | 24, 2011 | Trailblazers | 111 | Warriors | 84 |
| January | 28, 2011 | Lakers | 98 | Trailblazers | 107 |
| January | 29, 2011 | Mavericks | 108 | Trailblazers | 111 |
| February | 1, 2011 | Trailblazers | 106 | Warriors | 88 |
| February | 2, 2011 | Trailblazers | 119 | Clippers | 99 |
| February | 6, 2011 | Pelicans | 107 | Trailblazers | 99 |
| February | 13, 2011 | Trailblazers | 87 | Rockets | 107 |
| February | 14, 2011 | Trailblazers | 97 | Pistons | 128 |
| February | 18, 2011 | Rockets | 108 | Trailblazers | 94 |
| February | 21, 2011 | Trailblazers | 118 | Rockets | 116 |
| February | 22, 2011 | Lakers | 98 | Trailblazers | 102 |
| February | 24, 2011 | Trailblazers | 112 | Suns | 111 |
| February | 25, 2011 | Nuggets | 101 | Trailblazers | 97 |
| February | 27, 2011 | Trailblazers | 93 | Wolves | 103 |
| March | 1, 2011 | Heat | 67 | Trailblazers | 115 |
| March | 2, 2011 | Bulls | 81 | Trailblazers | 96 |
| March | 6, 2011 | Wolves | 118 | Trailblazers | 105 |
| March | 9, 2011 | Trailblazers | 115 | Pelicans | 124 |
| March | 10, 2011 | Thunder | 96 | Trailblazers | 108 |
| March | 12, 2011 | Trailblazers | 118 | Mavericks | 113 |
| March | 15, 2011 | Trailblazers | 99 | Grizzlies | 112 |
| March | 18, 2011 | Trailblazers | 91 | 76ers | 101 |
| March | 19, 2011 | Grizzlies | 108 | Trailblazers | 110 |
| March | 23, 2011 | Trailblazers | 90 | Thunder | 107 |
| March | 25, 2011 | Trailblazers | 103 | Bucks | 114 |
| March | 28, 2011 | Trailblazers | 99 | Nuggets | 121 |
| March | 30, 2011 | Pelicans | 87 | Trailblazers | 90 |
| March | 31, 2011 | Nets | 108 | Trailblazers | 111 |
| April | 2, 2011 | Trailblazers | 97 | Hornets | 113 |
| April | 5, 2011 | Trailblazers | 79 | Kings | 122 |
| April | 9, 2011 | Hawks | 123 | Trailblazers | 124 |
| April | 11, 2011 | Wolves | 116 | Trailblazers | 94 |
| April | 12, 2011 | Celtics | 92 | Trailblazers | 118 |
| April | 15, 2011 | Jazz | 106 | Trailblazers | 105 |
| April | 17, 2011 | Trailblazers | 104 | Knicks | 100 |
| April | 18, 2011 | Trailblazers | 106 | Pelicans | 112 |
| April | 21, 2011 | Trailblazers | 116 | Raptors | 100 |
| April | 22, 2011 | Trailblazers | 104 | Magic | 106 |
| April | 24, 2011 | Trailblazers | 98 | Kings | 107 |
| April | 27, 2011 | Trailblazers | 86 | Suns | 91 |
| April | 29, 2011 | Trailblazers | 107 | Clippers | 108 |
| April | 30, 2011 | Spurs | 119 | Trailblazers | 97 |