| month | day | visitor | score | home | score |
|---|
| November | 2, 2010 | Magic | 91 | Trailblazers | 113 |
| November | 4, 2010 | Pacers | 110 | Trailblazers | 109 |
| November | 6, 2010 | Trailblazers | 108 | Nets | 103 |
| November | 7, 2010 | Suns | 118 | Trailblazers | 90 |
| November | 10, 2010 | Nuggets | 91 | Trailblazers | 104 |
| November | 12, 2010 | Thunder | 92 | Trailblazers | 78 |
| November | 13, 2010 | Wizards | 93 | Trailblazers | 103 |
| November | 15, 2010 | Trailblazers | 105 | Hawks | 84 |
| November | 18, 2010 | Bucks | 102 | Trailblazers | 113 |
| November | 21, 2010 | Trailblazers | 104 | Spurs | 81 |
| November | 22, 2010 | Jazz | 120 | Trailblazers | 97 |
| November | 26, 2010 | Warriors | 83 | Trailblazers | 101 |
| November | 29, 2010 | Trailblazers | 93 | Thunder | 112 |
| December | 1, 2010 | Grizzlies | 92 | Trailblazers | 117 |
| December | 5, 2010 | Clippers | 74 | Trailblazers | 111 |
| December | 7, 2010 | Cavaliers | 94 | Trailblazers | 100 |
| December | 8, 2010 | Knicks | 98 | Trailblazers | 96 |
| December | 11, 2010 | Trailblazers | 83 | Jazz | 112 |
| December | 14, 2010 | Trailblazers | 105 | Pacers | 115 |
| December | 15, 2010 | Kings | 113 | Trailblazers | 107 |
| December | 16, 2010 | Rockets | 107 | Trailblazers | 122 |
| December | 18, 2010 | Trailblazers | 107 | Cavaliers | 106 |
| December | 19, 2010 | Pistons | 87 | Trailblazers | 78 |
| December | 22, 2010 | Trailblazers | 107 | Jazz | 125 |
| December | 23, 2010 | Spurs | 89 | Trailblazers | 86 |
| December | 26, 2010 | Trailblazers | 108 | Lakers | 115 |
| December | 28, 2010 | Trailblazers | 118 | Mavericks | 122 |
| December | 29, 2010 | Mavericks | 97 | Trailblazers | 115 |
| December | 31, 2010 | Hornets | 130 | Trailblazers | 105 |
| January | 3, 2011 | Trailblazers | 96 | Heat | 102 |
| January | 5, 2011 | Trailblazers | 102 | Wizards | 107 |
| January | 8, 2011 | Trailblazers | 110 | Celtics | 95 |
| January | 9, 2011 | Trailblazers | 102 | Bulls | 93 |
| January | 12, 2011 | Raptors | 86 | Trailblazers | 105 |
| January | 13, 2011 | Trailblazers | 111 | Nuggets | 103 |
| January | 15, 2011 | Trailblazers | 102 | Grizzlies | 114 |
| January | 17, 2011 | Trailblazers | 112 | Lakers | 114 |
| January | 20, 2011 | 76ers | 95 | Trailblazers | 102 |
| January | 21, 2011 | Warriors | 84 | Trailblazers | 111 |
| January | 23, 2011 | Suns | 94 | Trailblazers | 104 |
| January | 24, 2011 | Trailblazers | 98 | Warriors | 76 |
| January | 28, 2011 | Lakers | 108 | Trailblazers | 110 |
| January | 29, 2011 | Mavericks | 97 | Trailblazers | 119 |
| February | 1, 2011 | Trailblazers | 114 | Warriors | 88 |
| February | 2, 2011 | Trailblazers | 90 | Clippers | 97 |
| February | 6, 2011 | Pelicans | 101 | Trailblazers | 89 |
| February | 13, 2011 | Trailblazers | 112 | Rockets | 111 |
| February | 14, 2011 | Trailblazers | 106 | Pistons | 115 |
| February | 18, 2011 | Rockets | 97 | Trailblazers | 131 |
| February | 21, 2011 | Trailblazers | 127 | Rockets | 106 |
| February | 22, 2011 | Lakers | 85 | Trailblazers | 107 |
| February | 24, 2011 | Trailblazers | 91 | Suns | 88 |
| February | 25, 2011 | Nuggets | 101 | Trailblazers | 98 |
| February | 27, 2011 | Trailblazers | 90 | Wolves | 101 |
| March | 1, 2011 | Heat | 105 | Trailblazers | 103 |
| March | 2, 2011 | Bulls | 101 | Trailblazers | 99 |
| March | 6, 2011 | Wolves | 116 | Trailblazers | 99 |
| March | 9, 2011 | Trailblazers | 97 | Pelicans | 104 |
| March | 10, 2011 | Thunder | 101 | Trailblazers | 92 |
| March | 12, 2011 | Trailblazers | 98 | Mavericks | 102 |
| March | 15, 2011 | Trailblazers | 111 | Grizzlies | 115 |
| March | 18, 2011 | Trailblazers | 100 | 76ers | 77 |
| March | 19, 2011 | Grizzlies | 91 | Trailblazers | 114 |
| March | 23, 2011 | Trailblazers | 103 | Thunder | 102 |
| March | 25, 2011 | Trailblazers | 98 | Bucks | 92 |
| March | 28, 2011 | Trailblazers | 89 | Nuggets | 80 |
| March | 30, 2011 | Pelicans | 90 | Trailblazers | 106 |
| March | 31, 2011 | Nets | 124 | Trailblazers | 119 |
| April | 2, 2011 | Trailblazers | 106 | Hornets | 111 |
| April | 5, 2011 | Trailblazers | 90 | Kings | 108 |
| April | 9, 2011 | Hawks | 93 | Trailblazers | 107 |
| April | 11, 2011 | Wolves | 86 | Trailblazers | 104 |
| April | 12, 2011 | Celtics | 110 | Trailblazers | 109 |
| April | 15, 2011 | Jazz | 118 | Trailblazers | 101 |
| April | 17, 2011 | Trailblazers | 75 | Knicks | 104 |
| April | 18, 2011 | Trailblazers | 87 | Pelicans | 111 |
| April | 21, 2011 | Trailblazers | 97 | Raptors | 93 |
| April | 22, 2011 | Trailblazers | 102 | Magic | 93 |
| April | 24, 2011 | Trailblazers | 96 | Kings | 85 |
| April | 27, 2011 | Trailblazers | 75 | Suns | 89 |
| April | 29, 2011 | Trailblazers | 84 | Clippers | 94 |
| April | 30, 2011 | Spurs | 118 | Trailblazers | 102 |
| Post | 1, 2011 | Trailblazers | 69 | Thunder | 95 |
| Post | 2, 2011 | Trailblazers | 93 | Thunder | 94 |
| Post | 3, 2011 | Thunder | 82 | Trailblazers | 78 |
| Post | 4, 2011 | Thunder | 95 | Trailblazers | 92 |
| Post | 5, 2011 | Trailblazers | | Thunder | |
| Post | 6, 2011 | Thunder | | Trailblazers | |
| Post | 7, 2011 | Trailblazers | | Thunder | |