| month | day | visitor | score | home | score |
|---|
| November | 4, 2010 | Trailblazers | 98 | Celtics | 116 |
| November | 9, 2010 | Trailblazers | 98 | Warriors | 70 |
| November | 10, 2010 | Clippers | 93 | Trailblazers | 112 |
| November | 12, 2010 | Trailblazers | 101 | Lakers | 92 |
| November | 16, 2010 | Trailblazers | 101 | Pelicans | 121 |
| November | 18, 2010 | Trailblazers | 110 | Pacers | 114 |
| November | 19, 2010 | Grizzlies | 69 | Trailblazers | 99 |
| November | 20, 2010 | Trailblazers | 99 | Cavaliers | 125 |
| November | 21, 2010 | 76ers | 82 | Trailblazers | 98 |
| November | 23, 2010 | Bucks | 73 | Trailblazers | 89 |
| November | 25, 2010 | Trailblazers | 108 | Spurs | 103 |
| November | 26, 2010 | Trailblazers | 88 | Thunder | 96 |
| November | 28, 2010 | Trailblazers | 113 | Kings | 114 |
| November | 30, 2010 | Trailblazers | 111 | Heat | 112 |
| December | 1, 2010 | Trailblazers | 104 | Raptors | 109 |
| December | 5, 2010 | Trailblazers | 104 | Wizards | 123 |
| December | 8, 2010 | Spurs | 74 | Trailblazers | 102 |
| December | 9, 2010 | Pelicans | 108 | Trailblazers | 118 |
| December | 13, 2010 | Pacers | 111 | Trailblazers | 106 |
| December | 17, 2010 | Trailblazers | 105 | Wolves | 119 |
| December | 18, 2010 | Kings | 103 | Trailblazers | 106 |
| December | 19, 2010 | Trailblazers | 106 | Mavericks | 104 |
| December | 21, 2010 | Thunder | 105 | Trailblazers | 112 |
| December | 22, 2010 | Trailblazers | 97 | Thunder | 109 |
| December | 23, 2010 | Trailblazers | 69 | Suns | 99 |
| December | 25, 2010 | Raptors | 72 | Trailblazers | 118 |
| December | 29, 2010 | Thunder | 111 | Trailblazers | 121 |
| December | 31, 2010 | Warriors | 86 | Trailblazers | 106 |
| January | 1, 2011 | Grizzlies | 103 | Trailblazers | 107 |
| January | 5, 2011 | Trailblazers | 104 | Clippers | 76 |
| January | 8, 2011 | Hawks | 78 | Trailblazers | 108 |
| January | 9, 2011 | Wolves | 113 | Trailblazers | 103 |
| January | 11, 2011 | Celtics | 105 | Trailblazers | 95 |
| January | 12, 2011 | Trailblazers | 99 | Nuggets | 93 |
| January | 14, 2011 | Nets | 110 | Trailblazers | 108 |
| January | 15, 2011 | Trailblazers | 110 | Grizzlies | 109 |
| January | 18, 2011 | Hornets | 100 | Trailblazers | 124 |
| January | 25, 2011 | Trailblazers | 53 | Bucks | 81 |
| January | 29, 2011 | Trailblazers | 101 | Knicks | 110 |
| January | 31, 2011 | Jazz | 118 | Trailblazers | 91 |
| February | 1, 2011 | Trailblazers | 89 | Lakers | 115 |
| February | 16, 2011 | Trailblazers | 109 | Grizzlies | 123 |
| February | 17, 2011 | Wolves | 103 | Trailblazers | 115 |
| February | 20, 2011 | Trailblazers | 99 | Pistons | 125 |
| February | 22, 2011 | Trailblazers | 97 | Hawks | 117 |
| February | 25, 2011 | Trailblazers | 99 | Magic | 109 |
| February | 28, 2011 | Nuggets | 87 | Trailblazers | 118 |
| March | 2, 2011 | Rockets | 107 | Trailblazers | 111 |
| March | 3, 2011 | Nuggets | 109 | Trailblazers | 116 |
| March | 4, 2011 | Rockets | 84 | Trailblazers | 106 |
| March | 9, 2011 | Trailblazers | 103 | 76ers | 107 |
| March | 10, 2011 | Pistons | 81 | Trailblazers | 117 |
| March | 12, 2011 | Knicks | 92 | Trailblazers | 98 |
| March | 14, 2011 | Mavericks | 96 | Trailblazers | 124 |
| March | 15, 2011 | Trailblazers | 86 | Bulls | 88 |
| March | 16, 2011 | Wizards | 89 | Trailblazers | 85 |
| March | 18, 2011 | Trailblazers | 99 | Warriors | 83 |
| March | 22, 2011 | Trailblazers | 118 | Suns | 103 |
| March | 23, 2011 | Suns | 107 | Trailblazers | 111 |
| March | 25, 2011 | Trailblazers | 114 | Clippers | 94 |
| March | 26, 2011 | Trailblazers | 96 | Jazz | 108 |
| March | 27, 2011 | Mavericks | 99 | Trailblazers | 109 |
| March | 28, 2011 | Bulls | 116 | Trailblazers | 108 |
| March | 29, 2011 | Trailblazers | 99 | Mavericks | 113 |
| March | 31, 2011 | Spurs | 120 | Trailblazers | 102 |
| April | 2, 2011 | Trailblazers | 103 | Nuggets | 86 |
| April | 5, 2011 | Warriors | 86 | Trailblazers | 101 |
| April | 7, 2011 | Trailblazers | 93 | Kings | 116 |
| April | 9, 2011 | Trailblazers | 99 | Pelicans | 112 |
| April | 10, 2011 | Lakers | 114 | Trailblazers | 97 |
| April | 13, 2011 | Trailblazers | 71 | Jazz | 115 |
| April | 14, 2011 | Trailblazers | 95 | Hornets | 96 |
| April | 15, 2011 | Cavaliers | 75 | Trailblazers | 104 |
| April | 17, 2011 | Trailblazers | 99 | Nets | 127 |
| April | 18, 2011 | Suns | 97 | Trailblazers | 78 |
| April | 19, 2011 | Pelicans | 95 | Trailblazers | 98 |
| April | 21, 2011 | Jazz | 97 | Trailblazers | 86 |
| April | 22, 2011 | Trailblazers | 77 | Rockets | 81 |
| April | 23, 2011 | Lakers | 88 | Trailblazers | 69 |
| April | 24, 2011 | Trailblazers | 95 | Rockets | 97 |
| April | 26, 2011 | Magic | 102 | Trailblazers | 134 |
| April | 29, 2011 | Heat | 83 | Trailblazers | 108 |