| month | day | visitor | score | home | score |
|---|
| November | 3, 2016 | Pistons | 94 | Spurs | 102 |
| November | 4, 2016 | Spurs | 113 | Wolves | 111 |
| November | 7, 2016 | Spurs | 98 | Wolves | 110 |
| November | 8, 2016 | Hawks | 98 | Spurs | 96 |
| November | 11, 2016 | Suns | 107 | Spurs | 85 |
| November | 12, 2016 | Spurs | 106 | Grizzlies | 114 |
| November | 15, 2016 | Kings | 96 | Spurs | 95 |
| November | 17, 2016 | Spurs | 98 | Suns | 95 |
| November | 19, 2016 | Grizzlies | 107 | Spurs | 111 |
| November | 21, 2016 | Trailblazers | 83 | Spurs | 85 |
| November | 24, 2016 | Spurs | 99 | Knicks | 93 |
| November | 28, 2016 | Spurs | 90 | Hornets | 96 |
| November | 30, 2016 | Thunder | 105 | Spurs | 89 |
| December | 1, 2016 | Spurs | 109 | Celtics | 128 |
| December | 3, 2016 | Clippers | 88 | Spurs | 102 |
| December | 5, 2016 | Spurs | 115 | Nuggets | 101 |
| December | 7, 2016 | Spurs | 87 | Thunder | 116 |
| December | 9, 2016 | Spurs | 114 | Pelicans | 113 |
| December | 12, 2016 | Spurs | 102 | Thunder | 98 |
| December | 15, 2016 | Spurs | 104 | Pistons | 118 |
| December | 16, 2016 | Spurs | 79 | 76ers | 89 |
| December | 18, 2016 | Rockets | 106 | Spurs | 108 |
| December | 20, 2016 | Spurs | 93 | Raptors | 105 |
| December | 21, 2016 | Spurs | 84 | Lakers | 94 |
| December | 23, 2016 | Spurs | 108 | Trailblazers | 105 |
| December | 26, 2016 | Spurs | 97 | Cavaliers | 118 |
| December | 27, 2016 | Suns | 95 | Spurs | 112 |
| December | 30, 2016 | Pelicans | 71 | Spurs | 80 |
| January | 2, 2017 | Grizzlies | 98 | Spurs | 94 |
| January | 4, 2017 | Spurs | 125 | Magic | 126 |
| January | 5, 2017 | Knicks | 85 | Spurs | 98 |
| January | 8, 2017 | Spurs | 98 | Heat | 91 |
| January | 9, 2017 | Warriors | 86 | Spurs | 98 |
| January | 12, 2017 | Hornets | 85 | Spurs | 82 |
| January | 15, 2017 | Spurs | 89 | Kings | 92 |
| January | 17, 2017 | Spurs | 91 | Warriors | 106 |
| January | 21, 2017 | Nets | 85 | Spurs | 87 |
| January | 23, 2017 | Mavericks | 102 | Spurs | 119 |
| January | 26, 2017 | Spurs | 98 | Hawks | 113 |
| January | 28, 2017 | Spurs | 93 | Nets | 95 |
| January | 30, 2017 | Magic | 89 | Spurs | 114 |
| February | 1, 2017 | Lakers | 101 | Spurs | 112 |
| February | 5, 2017 | Warriors | 90 | Spurs | 96 |
| February | 6, 2017 | Spurs | 98 | Mavericks | 96 |
| February | 11, 2017 | Spurs | 99 | Lakers | 93 |
| February | 14, 2017 | Mavericks | 104 | Spurs | 111 |
| February | 17, 2017 | Pacers | 107 | Spurs | 91 |
| February | 20, 2017 | Spurs | 107 | Wizards | 99 |
| February | 21, 2017 | Raptors | 102 | Spurs | 116 |
| February | 25, 2017 | Cavaliers | 118 | Spurs | 114 |
| February | 27, 2017 | Kings | 89 | Spurs | 104 |
| February | 28, 2017 | Rockets | 108 | Spurs | 116 |
| March | 1, 2017 | Bucks | 118 | Spurs | 124 |
| March | 4, 2017 | Jazz | 99 | Spurs | 96 |
| March | 6, 2017 | Spurs | 97 | Jazz | 96 |
| March | 7, 2017 | Nuggets | 103 | Spurs | 110 |
| March | 8, 2017 | Spurs | 82 | Suns | 97 |
| March | 11, 2017 | Jazz | 93 | Spurs | 109 |
| March | 12, 2017 | Bulls | 100 | Spurs | 102 |
| March | 14, 2017 | Thunder | 97 | Spurs | 111 |
| March | 17, 2017 | Spurs | 87 | Clippers | 116 |
| March | 19, 2017 | Spurs | 98 | Jazz | 114 |
| March | 21, 2017 | Spurs | 84 | Kings | 97 |
| March | 23, 2017 | Spurs | 96 | Clippers | 127 |
| March | 25, 2017 | Wizards | 102 | Spurs | 117 |
| March | 26, 2017 | Spurs | 77 | Pacers | 103 |
| March | 28, 2017 | Spurs | 93 | Grizzlies | 138 |
| March | 31, 2017 | Wolves | 104 | Spurs | 107 |
| April | 2, 2017 | Heat | 90 | Spurs | 106 |
| April | 4, 2017 | Spurs | 110 | Pelicans | 97 |
| April | 7, 2017 | Pelicans | 101 | Spurs | 124 |
| April | 11, 2017 | Celtics | 112 | Spurs | 111 |
| April | 14, 2017 | Spurs | 75 | Bucks | 88 |
| April | 15, 2017 | Nuggets | 89 | Spurs | 87 |
| April | 19, 2017 | Spurs | 97 | Warriors | 94 |
| April | 21, 2017 | Lakers | 95 | Spurs | 89 |
| April | 22, 2017 | Spurs | 94 | Mavericks | 106 |
| April | 24, 2017 | Clippers | 90 | Spurs | 108 |
| April | 26, 2017 | Spurs | 96 | Bulls | 103 |
| April | 27, 2017 | 76ers | 87 | Spurs | 112 |
| April | 30, 2017 | Spurs | 100 | Trailblazers | 107 |
| May | 1, 2017 | Spurs | 99 | Rockets | 96 |
| Post | 1, 2017 | Thunder | 116 | Spurs | 122 |
| Post | 2, 2017 | Thunder | 116 | Spurs | 94 |
| Post | 3, 2017 | Spurs | 93 | Thunder | 120 |
| Post | 4, 2017 | Spurs | 110 | Thunder | 121 |
| Post | 5, 2017 | Thunder | 105 | Spurs | 93 |
| Post | 6, 2017 | Spurs | | Thunder | |
| Post | 7, 2017 | Thunder | | Spurs | |