| month | day | visitor | score | home | score |
|---|
| November | 3, 2015 | Jazz | 97 | Thunder | 112 |
| November | 5, 2015 | Raptors | 76 | Thunder | 86 |
| November | 8, 2015 | Thunder | 99 | Heat | 123 |
| November | 9, 2015 | Thunder | 107 | Clippers | 110 |
| November | 12, 2015 | Thunder | 74 | Blazers | 91 |
| November | 15, 2015 | Thunder | 92 | Nets | 97 |
| November | 17, 2015 | Wizards | 101 | Thunder | 98 |
| November | 20, 2015 | Pacers | 119 | Thunder | 121 |
| November | 22, 2015 | Suns | 105 | Thunder | 121 |
| November | 23, 2015 | Thunder | 97 | 76ers | 103 |
| November | 25, 2015 | Thunder | 104 | Nuggets | 118 |
| November | 26, 2015 | Pelicans | 83 | Thunder | 88 |
| November | 29, 2015 | Blazers | 98 | Thunder | 88 |
| November | 30, 2015 | Thunder | 113 | Spurs | 109 |
| December | 3, 2015 | Grizzlies | 85 | Thunder | 82 |
| December | 6, 2015 | Nets | 72 | Thunder | 96 |
| December | 7, 2015 | Spurs | 93 | Thunder | 101 |
| December | 10, 2015 | Rockets | 100 | Thunder | 96 |
| December | 12, 2015 | Spurs | 97 | Thunder | 91 |
| December | 14, 2015 | Thunder | 104 | Jazz | 93 |
| December | 17, 2015 | Thunder | 89 | Grizzlies | 103 |
| December | 18, 2015 | Magic | 86 | Thunder | 89 |
| December | 20, 2015 | Celtics | 107 | Thunder | 104 |
| December | 23, 2015 | Cavaliers | 99 | Thunder | 103 |
| December | 26, 2015 | Grizzlies | 109 | Thunder | 88 |
| December | 28, 2015 | Thunder | 67 | Wolves | 93 |
| December | 31, 2015 | Thunder | 88 | Knicks | 100 |
| January | 1, 2016 | Hawks | 105 | Thunder | 95 |
| January | 4, 2016 | Nuggets | 104 | Thunder | 109 |
| January | 6, 2016 | Pistons | 91 | Thunder | 100 |
| January | 8, 2016 | Clippers | 82 | Thunder | 96 |
| January | 11, 2016 | Wolves | 109 | Thunder | 90 |
| January | 14, 2016 | Bulls | 125 | Thunder | 112 |
| January | 15, 2016 | Mavericks | 91 | Thunder | 84 |
| January | 17, 2016 | Thunder | 71 | Mavericks | 74 |
| January | 18, 2016 | Thunder | 113 | Rockets | 111 |
| January | 20, 2016 | Thunder | 81 | Hornets | 101 |
| January | 23, 2016 | Thunder | 90 | Nuggets | 118 |
| January | 24, 2016 | Thunder | 118 | Lakers | 107 |
| January | 26, 2016 | Nuggets | 120 | Thunder | 108 |
| January | 29, 2016 | Kings | 74 | Thunder | 95 |
| January | 30, 2016 | Thunder | 104 | Jazz | 108 |
| February | 2, 2016 | Thunder | 90 | Bucks | 86 |
| February | 5, 2016 | Thunder | 118 | Suns | 97 |
| February | 6, 2016 | Warriors | 99 | Thunder | 101 |
| February | 11, 2016 | Thunder | 98 | Cavaliers | 106 |
| February | 14, 2016 | Thunder | 102 | Warriors | 107 |
| February | 17, 2016 | Jazz | 112 | Thunder | 127 |
| February | 19, 2016 | Lakers | 119 | Thunder | 109 |
| February | 23, 2016 | Wolves | 115 | Thunder | 113 |
| February | 24, 2016 | Thunder | 108 | Raptors | 117 |
| February | 26, 2016 | Thunder | 106 | Warriors | 98 |
| February | 28, 2016 | Thunder | 96 | Pelicans | 87 |
| March | 1, 2016 | Lakers | 105 | Thunder | 112 |
| March | 3, 2016 | Pelicans | 78 | Thunder | 101 |
| March | 4, 2016 | Thunder | 111 | Magic | 108 |
| March | 6, 2016 | Clippers | 97 | Thunder | 118 |
| March | 10, 2016 | Thunder | 86 | Blazers | 93 |
| March | 13, 2016 | Thunder | 91 | Suns | 96 |
| March | 14, 2016 | Thunder | 94 | Spurs | 119 |
| March | 16, 2016 | Thunder | 89 | Wolves | 103 |
| March | 19, 2016 | Hornets | 108 | Thunder | 115 |
| March | 23, 2016 | Blazers | 85 | Thunder | 84 |
| March | 24, 2016 | Thunder | 86 | Pistons | 101 |
| March | 26, 2016 | 76ers | 76 | Thunder | 80 |
| March | 28, 2016 | Thunder | 95 | Bulls | 109 |
| March | 31, 2016 | Thunder | 95 | Wizards | 117 |
| April | 2, 2016 | Rockets | 111 | Thunder | 101 |
| April | 4, 2016 | Thunder | 94 | Grizzlies | 101 |
| April | 5, 2016 | Thunder | 87 | Hawks | 86 |
| April | 7, 2016 | Thunder | 116 | Clippers | 108 |
| April | 10, 2016 | Thunder | 81 | Kings | 84 |
| April | 12, 2016 | Heat | 83 | Thunder | 111 |
| April | 14, 2016 | Thunder | 83 | Celtics | 115 |
| April | 16, 2016 | Thunder | 85 | Mavericks | 80 |
| April | 17, 2016 | Thunder | 90 | Rockets | 107 |
| April | 19, 2016 | Bucks | 89 | Thunder | 85 |
| April | 23, 2016 | Kings | 90 | Thunder | 102 |
| April | 26, 2016 | Thunder | 76 | Pelicans | 88 |
| April | 28, 2016 | Knicks | 88 | Thunder | 91 |
| April | 29, 2016 | Mavericks | 97 | Thunder | 78 |
| May | 1, 2016 | Thunder | 93 | Pacers | 98 |