| month | day | visitor | score | home | score |
|---|
| November | 2, 2012 | Bobcats | 96 | Lakers | 111 |
| November | 4, 2012 | 76ers | 104 | Lakers | 112 |
| November | 5, 2012 | Lakers | 89 | Jazz | 83 |
| November | 7, 2012 | Bulls | 121 | Lakers | 114 |
| November | 8, 2012 | Lakers | 96 | Mavericks | 92 |
| November | 9, 2012 | Lakers | 85 | Bucks | 111 |
| November | 10, 2012 | Hawks | 109 | Lakers | 97 |
| November | 12, 2012 | Lakers | 90 | Rockets | 95 |
| November | 14, 2012 | Mavericks | 107 | Lakers | 112 |
| November | 15, 2012 | Nuggets | 101 | Lakers | 111 |
| November | 17, 2012 | Kings | 107 | Lakers | 133 |
| November | 18, 2012 | Lakers | 87 | Grizzlies | 101 |
| November | 23, 2012 | Lakers | 100 | 76ers | 92 |
| November | 25, 2012 | Lakers | 108 | Mavericks | 117 |
| November | 26, 2012 | Lakers | 93 | Warriors | 105 |
| November | 27, 2012 | Warriors | 111 | Lakers | 113 |
| November | 30, 2012 | Lakers | 109 | Suns | 107 |
| December | 4, 2012 | Warriors | 90 | Lakers | 86 |
| December | 7, 2012 | Lakers | 123 | Rockets | 99 |
| December | 11, 2012 | Spurs | 98 | Lakers | 111 |
| December | 12, 2012 | Wizards | 103 | Lakers | 91 |
| December | 13, 2012 | Lakers | 84 | Thunder | 107 |
| December | 15, 2012 | Nuggets | 109 | Lakers | 93 |
| December | 17, 2012 | Magic | 94 | Lakers | 99 |
| December | 19, 2012 | Lakers | 89 | Nets | 92 |
| December | 21, 2012 | Lakers | 81 | Pistons | 112 |
| December | 22, 2012 | Kings | 115 | Lakers | 130 |
| December | 25, 2012 | Lakers | 126 | Nuggets | 107 |
| December | 30, 2012 | Raptors | 82 | Lakers | 122 |
| January | 1, 2013 | Lakers | 99 | Hornets | 117 |
| January | 2, 2013 | Rockets | 90 | Lakers | 86 |
| January | 4, 2013 | Lakers | 101 | Grizzlies | 118 |
| January | 5, 2013 | Celtics | 90 | Lakers | 108 |
| January | 8, 2013 | Lakers | 91 | Clippers | 78 |
| January | 12, 2013 | Lakers | 91 | Jazz | 98 |
| January | 14, 2013 | Nets | 88 | Lakers | 96 |
| January | 15, 2013 | Lakers | 107 | Spurs | 112 |
| January | 16, 2013 | Lakers | 123 | Blazers | 115 |
| January | 18, 2013 | Lakers | 116 | Knicks | 114 |
| January | 19, 2013 | Pacers | 102 | Lakers | 112 |
| January | 20, 2013 | Lakers | 101 | Thunder | 109 |
| January | 25, 2013 | Suns | 96 | Lakers | 97 |
| January | 29, 2013 | Lakers | 122 | Kings | 94 |
| January | 30, 2013 | Lakers | 104 | Bulls | 111 |
| February | 2, 2013 | Cavaliers | 100 | Lakers | 84 |
| February | 4, 2013 | Hornets | 98 | Lakers | 100 |
| February | 6, 2013 | Grizzlies | 107 | Lakers | 100 |
| February | 13, 2013 | Grizzlies | 99 | Lakers | 90 |
| February | 14, 2013 | Rockets | 106 | Lakers | 103 |
| February | 19, 2013 | Lakers | 110 | Nuggets | 82 |
| February | 22, 2013 | Jazz | 93 | Lakers | 98 |
| February | 24, 2013 | Lakers | 111 | Wizards | 109 |
| February | 26, 2013 | Lakers | 97 | Hornets | 110 |
| February | 28, 2013 | Knicks | 113 | Lakers | 96 |
| March | 6, 2013 | Heat | 112 | Lakers | 90 |
| March | 7, 2013 | Wolves | 98 | Lakers | 97 |
| March | 8, 2013 | Lakers | 74 | Raptors | 90 |
| March | 10, 2013 | Pistons | 117 | Lakers | 113 |
| March | 12, 2013 | Lakers | 109 | Blazers | 112 |
| March | 13, 2013 | Lakers | 92 | Wolves | 112 |
| March | 15, 2013 | Bucks | 88 | Lakers | 69 |
| March | 18, 2013 | Mavericks | 99 | Lakers | 85 |
| March | 20, 2013 | Lakers | 102 | Pacers | 112 |
| March | 21, 2013 | Lakers | 85 | Cavaliers | 105 |
| March | 25, 2013 | Lakers | 107 | Wolves | 98 |
| March | 28, 2013 | Hornets | 98 | Lakers | 101 |
| April | 2, 2013 | Lakers | 89 | Magic | 110 |
| April | 5, 2013 | Blazers | 93 | Lakers | 135 |
| April | 6, 2013 | Lakers | 102 | Heat | 111 |
| April | 7, 2013 | Lakers | 97 | Bobcats | 91 |
| April | 9, 2013 | Spurs | 85 | Lakers | 108 |
| April | 10, 2013 | Lakers | 104 | Suns | 115 |
| April | 11, 2013 | Clippers | 103 | Lakers | 101 |
| April | 13, 2013 | Jazz | 109 | Lakers | 105 |
| April | 15, 2013 | Clippers | 104 | Lakers | 116 |
| April | 16, 2013 | Blazers | 88 | Lakers | 108 |
| April | 17, 2013 | Lakers | 114 | Celtics | 91 |
| April | 19, 2013 | Lakers | 98 | Hawks | 112 |
| April | 23, 2013 | Lakers | 87 | Spurs | 122 |
| April | 24, 2013 | Thunder | 84 | Lakers | 113 |
| April | 25, 2013 | Wolves | 90 | Lakers | 81 |
| April | 29, 2013 | Lakers | 86 | Warriors | 70 |